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Active Ingredient(s): Desvenlafaxine Succinate
FDA Approved: February 29, 2008
Category: Antidepressant

Pristiq Overview

Desvenlafaxine (brand name: Pristiq), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.[1] Contents 1 Medical uses 2 Adverse effects 3 Pharmacology 4 Approval sta...

Read more Pristiq Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Pristiq Forums: RSS Feed

Weight gain on Pristiq??
I have been on Pristiq now since November of 2008...not quite 5 months...and I have put on 15 lbs since starting it. DESPITE working out with a trainer at the gym twice a week weight training, 3 days a week of cardio AND counting calories. My doc assured me that I would also have a decreased appetite on Pristiq, which I have yet to find he has now increased my dosage to 400 mg. Does anyone have anything to add to this?? I'm just frustrated! ## i was switched to pristiq a few months ago and just recently wellbutrin was added - i take 1 of each pill per day - it has done nothing to me in gaining weight - i am continuously losing but i have some emtional things going on right now which i believe the weight loss is contributed too - unfortunately i have run into many that have...
Updated 1 minute ago.
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atrial fibrillation ## Pristiq, which contains the active ingredient Desvenlafaxine, is an antidepressant. Some of the most common side effects include: nausea, drowsiness, sexual dysfunction and constipation. ## For 18 years I have been taking Prozac. Each time I have attempted to change, under the care of a physician, I've touched the bottom of depression again. During the last several years my dosage has been upped to 40 mg in the AM and 40 in the PM. I've suffered anxiety, expecially upon awakening in the morning. In the last 10 years I've been divorced from a man with passive-aggressive tendancies. I go to a well reputed psychologist,exercise and eat well. I regularly meditate and do daily journaling,etc. I'm now married to a good person. My psychologist, chiropract...
Updated 16 days ago.
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pristiq and sleeplessness
have been on pristiq a couple of months and am feeling good but have recently not been able to sleep.its weird as i don't feel tired? is this a common side effect and if so is there something i can do for with without medication? ## Hello, Gettingthere! How are you? Pristiq is an SNRI antidepressant and most such medications can cause ROL, which is REM onset latency. That means you take longer to enter the restful REM phase of sleep and are in it for a shorter period of time. It also tends to cause vivid dreaming. If you aren't tired, I have to wonder if maybe you are sleeping, but just dreaming and thinking you aren't? I could be wrong, but I did find this happening to me, sometimes, while taking Prozac. Other side effects may include nausea, dizziness, headache, dry mouth ...
Updated 18 days ago.
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Acetylcholine interact with Prestiq?
Does Acetylcholine interact with Prestiq? ## Hello, Theotherstars! How are you? I didn't find any interactions or problems listed between them, but it's always best to double check such information to be sure. Pristiq contains the active ingredient Desvenlafaxine, it is most commonly used to treat depression. Side effects may include nausea, dizziness, dry mouth and weight changes. Is there anything else I can help with?
Updated 21 days ago.
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Does pristiq come in lower doses than 50mil?
I have been prescribed 50mil of depression drug Pristiq. I have all of my medications balanced to a good level. (I have been diagnosed as a manic,depressive, stuck in the depressive state, with very little or no manic episodes for years.) However when I take my new Pristiq medication, it brings me out of my depression, but I can tell the 50 mil. is way too powerful and it just sends my body into orbit! My body is stressed to the limit, I am anxious, and overloaded to the max. I need to find out if Pristiq comes in a lower dosages such as 10mil or such, or there is another matching medication that does. ## Hello, Debi! How are you? No, that is the lowest dose available. However, what you are experiencing could be the normal side effects that will start to wear off after a month, or so. M...
Updated 23 days ago.
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Pristiq 50 Mg
just want to know if pritiq can cause numbness in the feet and toes ## No, those aren't normal side effects of this medication. If that's what you're experiencing, then you need to talk to your doctor as soon as possible to see what's causing it. That could be the sign of a dangerous reaction, or due to some other medical condition that requires treatment. Learn more Pristiq details here. How often does it occur? ## Pristiq can most definitely cause tingling in the legs and toes. I know because I have it now and since starting this poison.
Updated 23 days ago.
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Switched from Pristiq to Wellbutrin XL
I'm adding a post to hopefully help someone as reading other people's posts has been very helpful/comforting to me! I have been on 50 mg of Pristiq for 5 years and I just made the transition to Wellbutrin xl at 300 mg. My doc switched me because my libido was becoming obsolete and wellbutrin is not supposed to adversely effect this. He had me start by overlapping the two meds for Week 1...Maintaining 50 mg of pristiq and adding Wellbutrin XL at 150 mg. I felt completely fine, didn't notice anything different. Week 2-I was to go up to 300 mg of Wellbutrin XL and completely stop taking the Pristiq. That didn't work. 1.5 days in I was dizzy, minor brain zap feeling (but not as intense as when i would miss a pristiq pill in the past) feeling super emotional (weepy) so much t...
Updated 25 days ago.
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Weaning off pristiq
I just wanted to tell all of you trying to get off pristiq, its possible. I was on pristiq for severe panic attacks for 6 months. It saved my life. It gave me a chance to slow down my career, gave me a huge wakeup call. This drug put a cloud over my brain. I was not my happy, fun loving self. I was like a step ford wife. You cant wean off this pill. I was on 50mg. I did every other day for a month. Every third day for two weeks then cold turkey. It really was not so bad. I layer on my couch for three days, cried a bit and watched movies. I'm happily on all holistic medications, no longer a slave to pristiq. If I can beat anxiety, anyone can. My biggest advice.. Exercise. Next, surround yourself with positive people. Three, talk out your problems. Good luck. ## Fantastic advice and v...
Updated 1 month ago.
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anxiety worse on pristiq
6 months ago my doctor switched me to Pristiq xr 100mg to replace Effexor xr 75mg. The med. always seems to stop working after abot 6 or7 months or so. I have not seen my doc in 6 months and i've noticed my anxiey is terrible. I don't trust co-workers and am paronoid that when I walk into work, they are thinking bad thoughts of me. This stops me from opening up/making friends. My co-workers eventually end up not liking me. I hope someone can relate with me. 5 years ago this was just depression, and the in the last 3 years whatever anxiety I may have had has slowly gotten worse. Is this typical of these medications? I've even considered divorcing just to start a new life/new chapter. I hope someone can help. thank you. ## My wife of 13 years started acting irrational, had ras...
Updated 1 month ago.
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pristiq is it a narcotic
is pristiq a narcotic I NEED TO KNOW ## Hello, Joe! How are you? No, Pristiq contains the active ingredient Desvenlafaxine, is it an SNRI antidepressant. Side effects may include nausea, dizziness, headache, dry mouth and weight changes. Is there anything else I can help with?
Updated 2 months ago.
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Possible Dosages for this and Related Drugs:

Desvenlafaxine Succinate
  • Tablet: 100mg, 50mg
  • Tablet, Extended Release: 100mg, 50 Mg. And 100 Mg., 50mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Desvenlafaxine Succinate or a similar ingredient: (3 results)

Possibly related Pristiq Topics:

pristiq and weight gain I started pristiq approx 5 weeks ago and altho my doctor assured me that it was a weight neutral drug I have easily gain...  72
Pristiq This is NOT a good medicine. I felt more depressed on it and had several side effects, nausea, lack of appetite, dizzine...  39
pristiq for depression and anxiety did not work My Son went to the Dr. for anxiety and depression, pristiq created more problems for him, panic attacks, insomnia, loss ...  9
pristiq withdrawl Hi all, I was on 150 of pristiq and have been tapering off for two months. Last week I went from 50 to 25 for about 4 da...  5
Pristiq an Libido- Advice Needed! I have been taking Pristiq for about 3 years now due Anxiety attacks. After taking the drug for afew days I had the wors...  5
Pristiq Withdrawls I have been on Pristiq for about 4 years and was on levoxyl for a few years prior. I had started taking Sarafem 925mg) a...  4
Pristiq and hot flushes/flashes I have been on this for 5 days. The last 3 days I have been having hot flushes and they have been getting more frequent....  4
Pristiq - fatigue I have started taking pristiq about 6 weeks ago and I have noticed in the last week or so that I have been extremely fat...  4
pristiq withdrawal I am going through menopause and my doctor switched me from Prestiq to Zoloft. The Prestiq wasn't helping the anxiet...  3
Pristiq and more depressed I have been on Pristiq 50 mg now for 9 days and I'm getting more depressed than when I started. Will this pass? ## A...  3