Active Ingredient(s): Desvenlafaxine Succinate
FDA Approved: * February 29, 2008
Pharm Company: * WYETH PHARMS INC
Category: Antidepressant

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Pristiq Overview

Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.[1] It is an example of evergreening. Contents 1 Medical use...

Read more Pristiq Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Pristiq Forums: RSS Feed

132 Replies RSS
atrial fibrillation ## Pristiq, which contains the active ingredient Desvenlafaxine, is an antidepressant. Some of the most common side effects include: nausea, drowsiness, sexual dysfunction and constipation. ## For 18 years I have been taking Prozac. Each time I have attempted to change, under the care of a physician, I've touched the bottom of depression again. During the last several years my dosage has been upped to 40 mg in the AM and 40 in the PM. I've suffered anxiety, expecially upon awakening in the morning. In the last 10 years I've been divorced from a man with passive-aggressive tendancies. I go to a well reputed psychologist,exercise and eat well. I regularly meditate and do daily journaling,etc. I'm now married to a good person. My psychologist, chiropract...
Updated 6 minutes ago.
Switching from zoloft to pristiq
1 Reply RSS
After 6 yrs on zoloft it no longer helps much. I felt great for 2-3 years but know it time for a change. I had a genetic test done and my doctor decided to try me on pristiq. Reduced zoloft to 50 mg and started 50mg prestiq today. Then keep reducing zoloft. Anyways I'm freaking out about being on 2 antidepressant at the same time (serotonin syndrome) and am also scared of withdrawal symptoms from the zoloft. Is there anybody who's had a positive experience switching from ssri to snri?? ## Doing a gradual change by tapering up and down is normal, as long as your doctor is monitoring you to keep an eye out for any possible problems. It should also eliminate the worst of any withdrawal symptoms, though you may still experience some nausea, diarrhea, and anxiety, according to the NI...
Updated 5 days ago.
Pristiq dose increase. Really need advice!
3 Replies RSS
I have depressive disorder and generalized anxiety disorder, and am currently taking Pristiq 50mg once daily, along with Buspar 10mg twice daily. I was taking 300mg Wellbutrin XL with that, but my psych dr thought it my be exacerbating my anxiety. A few weeks ago she decreased my Wellbutrin dosage to 150mg and changed it to the SR formula. Now she wants me to quit the Wellbutrin completely and up my Pristiq.. I I have been on 50mg Pristiq once daily for almost a year now, and I don't really think it's been working for me for some time. When I first started taking it, I switched from Zoloft 100mg and found my mood improved quickly. After a while I think I went more towards either being depressed or apathetic, but yet couldn't actually recognize until my husband told me that I...
Updated 5 days ago.
Pristiq an Libido- Advice Needed!
7 Replies RSS
I have been taking Pristiq for about 3 years now due Anxiety attacks. After taking the drug for afew days I had the worst anxiety i'd ever had, i had horrible nightmares, nausea and bad headaches these symptoms completely disapeared by about a month after starting it. After the first month life was great I was back to my normal self, I could eat food again (which was the main reason for my anxiety attacks). For about 2 years it worked great for me with minimal side effects mainly brain ticks if i took the pristiq too late in the day, If i completely forgot the tablet I would be bed ridden the entire next day with terrible brain ticks, headaches and nausea, although 99 percent of the time I felt fine. I fell pregnant with my now 9 month old baby girl and decided to stay on pristiq wh...
Updated 5 days ago.
Weight gain on Pristiq??
552 Replies RSS
I have been on Pristiq now since November of 2008...not quite 5 months...and I have put on 15 lbs since starting it. DESPITE working out with a trainer at the gym twice a week weight training, 3 days a week of cardio AND counting calories. My doc assured me that I would also have a decreased appetite on Pristiq, which I have yet to find he has now increased my dosage to 400 mg. Does anyone have anything to add to this?? I'm just frustrated! ## i was switched to pristiq a few months ago and just recently wellbutrin was added - i take 1 of each pill per day - it has done nothing to me in gaining weight - i am continuously losing but i have some emtional things going on right now which i believe the weight loss is contributed too - unfortunately i have run into many that have...
Updated 12 days ago.
pristiq vs venlafaxine
1 Reply RSS
I was on venlafaxine 37mg and it made me more worse. I was on cymbalta and that worked great but it stopped working and now i am on zoloft but it's not working. I am thinking about pristiq but is it worth it over venlafaxine? ## It is a similar medication in the same class, but it is not exactly the same, so it may work better for you. The FDA lists its typical side effects as possibly including nausea, dizziness, headache, dry mouth, mood swings, and weight changes. Is there anything else I can help with?
Updated 13 days ago.
Pristiq Night Sweats
6 Replies RSS
Hi all, I have been on Pristiq for 5+ years. Soon after I began, I started dealing with night sweats. Not just mild sweat - I'm talking my PJs and sheets are drenched. It is awful! The night sweats have come and go over the years but are currently very bad. I can't seem to get much information on the internet about this side effect being an issue for many people. Has anyone else experienced night sweats from taking Pristiq? ## Hi Erin, According to the manufacturer, sweating is actually one of the most common side effects people experience from taking Pristiq (Desvenlafaxine). However, happens to list "sweating" as both a 'general' and 'serious' side effect here: Have you already made your doctor ...
Updated 18 days ago.
Pristiq - By accident took a double dose today
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Hi. I think I took a double dose of my pristiq 100mgs today. I am feeling pretty anxious now as I am worried about what could happen?
Updated 20 days ago.
Needing help in purchasing a perscription I cannot afford
3 Replies RSS
I have no insurance and have to purchase prestig which is quite expensive. Is there help for those like me to get assistance in helping with my perscription of Prestige ## Pristiq contains the active ingredient Desvenlafaxine, it is an antidepressant, which is manufactured by Pfizer. And yes, they have a program to assist uninsured individuals that require their medications, they offer several different programs and the eligibility requirements can vary for each, but you can contact them for more information at 866-706-2400. Many of the programs just require that you have no insurance or prescription coverage and then they usually go by a sliding fee scale, which is based on your income. So, some people receive their medications completely free, while others pay a small percentage of th...
Updated 24 days ago.
2 Replies RSS
I am on 200 a day an I've stoped taking them as I worked so hard to loose 62kg an I was told this drug wouldn't make me gain weight. I am on day 4 without them an I am seriously dizzy an I am wanting to know how much longer till the drug is out of my system? ## Pristiq contains the active ingredient Desvenlafaxine, it is an SNRI antidepressant. The withdrawal effects, if you were taking them for a long period of time, especially at such a high dosage, can take about a month to completely wear off. Though, they will gradually improve and not be so severe, as your body adjusts to no longer having the medication. You should also be careful to watch for rebound depression and anxiety symptoms. Is there anything else I can help with? ## What is prestiqe, and is it make bad side effec...
Updated 1 month ago.

Possible Dosages for this and Related Drugs:

Desvenlafaxine Succinate
  • Tablet: 100mg, 50mg
  • Tablet, Extended Release: 100mg, 25mg, 50 Mg. And 100 Mg., 50mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Pristiq: (6 results)

Sorted by National Drug Code
  • 0008-1211 24 Hr Pristiq 50 mg Extended Release Tablet by Wyeth Pharmaceuticals Inc., a Subsidiary of Pfizer Inc.
  • 0008-1222 24 Hr Pristiq 100 mg Extended Release Tablet by Wyeth Pharmaceuticals Inc., a Subsidiary of Pfizer Inc.
  • 35356-491 24 Hr Pristiq 50 mg Extended Release Tablet by Lake Erie Medical & Surgical Supply Dba Quality Care Products LLC
  • 35356-567 24 Hr Pristiq 100 mg Extended Release Tablet by Lake Erie Medical Dba Quality Care Products LLC
  • 54868-2932 24 Hr Pristiq 50 mg Extended Release Tablet by Physicians Total Care, Inc.
  • 55154-4230 24 Hr Pristiq 50 mg Extended Release Tablet by Cardinal Health

Other drugs which contain Desvenlafaxine Succinate or a similar ingredient: (3 results)

Possibly related Pristiq Topics:

pristiq and weight gain I started pristiq approx 5 weeks ago and altho my doctor assured me that it was a weight neutral drug I have easily gain... 74 replies
Pristiq This is NOT a good medicine. I felt more depressed on it and had several side effects, nausea, lack of appetite, dizzine... 41 replies
pristiq for depression and anxiety did not work My Son went to the Dr. for anxiety and depression, pristiq created more problems for him, panic attacks, insomnia, loss ... 13 replies
Pristiq an Libido- Advice Needed! I have been taking Pristiq for about 3 years now due Anxiety attacks. After taking the drug for afew days I had the wors... 7 replies
Pristiq Night Sweats Hi all, I have been on Pristiq for 5+ years. Soon after I began, I started dealing with night sweats. Not just mild swea... 6 replies
pristiq is it a narcotic is pristiq a narcotic I NEED TO KNOW ## Hello, Joe! How are you? No, Pristiq contains the active ingredient Desvenlafaxi... 5 replies
pristiq withdrawl Hi all, I was on 150 of pristiq and have been tapering off for two months. Last week I went from 50 to 25 for about 4 da... 5 replies
Pristiq Withdrawls I have been on Pristiq for about 4 years and was on levoxyl for a few years prior. I had started taking Sarafem 925mg) a... 4 replies
Pristiq and hot flushes/flashes I have been on this for 5 days. The last 3 days I have been having hot flushes and they have been getting more frequent.... 4 replies
Pristiq - fatigue I have started taking pristiq about 6 weeks ago and I have noticed in the last week or so that I have been extremely fat... 4 replies