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Active Ingredient(s): Desvenlafaxine Succinate
FDA Approved: February 29, 2008
Category: Antidepressant

Pristiq Overview

Desvenlafaxine (brand name: Pristiq), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.[1] Contents 1 Medical uses 2 Adverse effects 3 Pharmacology 4 Appro...

Read more Pristiq Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Pristiq Forums: RSS Feed

Pristiq and Buspar
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Is it safe to take 100mg of Pristiq and 10mg of Buspar and 250mg of Seroquel together? I didn't know how much serotonin all those combined would be or if those 3 meds are ok to take together. Thanks!
Updated 4 minutes ago.
Weaning off pristiq
371 Replies RSS
I just wanted to tell all of you trying to get off pristiq, its possible. I was on pristiq for severe panic attacks for 6 months. It saved my life. It gave me a chance to slow down my career, gave me a huge wakeup call. This drug put a cloud over my brain. I was not my happy, fun loving self. I was like a step ford wife. You cant wean off this pill. I was on 50mg. I did every other day for a month. Every third day for two weeks then cold turkey. It really was not so bad. I layer on my couch for three days, cried a bit and watched movies. I'm happily on all holistic medications, no longer a slave to pristiq. If I can beat anxiety, anyone can. My biggest advice.. Exercise. Next, surround yourself with positive people. Three, talk out your problems. Good luck. ## Fantastic advice and v...
Updated 2 days ago.
prestiq not helping
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I recently switched from being on/off Prozac for 20 years to taking Celexa, all I wanted to do was sleep all the time after starting it. The Dr. put me on Prestiq, I am on day 15 and not noticing a difference, still want to sleep. Any suggestions on what to try next? ## It will take about 4 to 6 weeks, before this medication reaches its full level of efficacy in your body, for you to know if it's going to work for you. If you don't see any improvement after being on it for at least 4 weeks, then you should consult your doctor. The FDA lists ts typical side effects as possibly including nausea, dizziness, headache, dry mouth, mood swings and weight changes. What are you taking it to treat?
Updated 3 days ago.
Weight gain on Pristiq??
536 Replies RSS
I have been on Pristiq now since November of 2008...not quite 5 months...and I have put on 15 lbs since starting it. DESPITE working out with a trainer at the gym twice a week weight training, 3 days a week of cardio AND counting calories. My doc assured me that I would also have a decreased appetite on Pristiq, which I have yet to find he has now increased my dosage to 400 mg. Does anyone have anything to add to this?? I'm just frustrated! ## i was switched to pristiq a few months ago and just recently wellbutrin was added - i take 1 of each pill per day - it has done nothing to me in gaining weight - i am continuously losing but i have some emtional things going on right now which i believe the weight loss is contributed too - unfortunately i have run into many that have...
Updated 10 days ago.
pristiq cold turkey adderall xanax
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The men and women of the US, Coalition and NATO forces engaged in military operations and civilian affairs around the world are my heroes - with that said, there are also folks that operate behind the scenes supporting our country's heroes. These folks, are Civilians. I supported US and Coalition forces in a civilian capacity through 6 consecutive civilian deployments to Iraq during Operation Iraqi Freedom and Operation New Dawn. I also supported US and NATO forces in a civilian capacity through 4 consecutive deployments to Afghanistan during Operation Enduring Freedom. We don't hear much about the civilians, and as one of those civilians, I can tell you first hand that the mental, emotional and physical suffering and injuries go mostly unreported. Making matters worse, most of ...
Updated 25 days ago.
new to pristiq
4 Replies RSS
Just started last night 50 mg. Took around 8:30 pm. I woke around 1:50am had to use bathroom. Then tossed, turned all night, brain won't shut off. I think I finally feel asleep around 8:30am woke up 9:40 am... could not get out of bed. Made myself get up. Feel weird, tired but awake. I don't like this feeling. I am laying in bed and was trying to nap since 2pm, no freaking luck! I just want to sleep!!! ## I am very sorry about the problem that you're having. However, this does occur frequently, when starting such a medication. It tends to alter how soon you enter the REM sleep phase and how much time you spent in it, which sometimes results in sleep that isn't restful and/or insomnia. However, it usually improves after about 3 to 4 weeks, once your body gets used to the ...
Updated 28 days ago.
123 Replies RSS
atrial fibrillation ## Pristiq, which contains the active ingredient Desvenlafaxine, is an antidepressant. Some of the most common side effects include: nausea, drowsiness, sexual dysfunction and constipation. ## For 18 years I have been taking Prozac. Each time I have attempted to change, under the care of a physician, I've touched the bottom of depression again. During the last several years my dosage has been upped to 40 mg in the AM and 40 in the PM. I've suffered anxiety, expecially upon awakening in the morning. In the last 10 years I've been divorced from a man with passive-aggressive tendancies. I go to a well reputed psychologist,exercise and eat well. I regularly meditate and do daily journaling,etc. I'm now married to a good person. My psychologist, chiropract...
Updated 1 month ago.
Tight chest, shortness of breath
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I've been on Effexor for 11-12yrs for anxiety & myoclonus til less than 1 week ago I changed to pristiq, due to the horrible disabling side effects of Effexor (for 3 wks) if I miss 1 tablet. Pristiq has the same metaboliser as Effexor but diff main ingredient. So I had no noticeable side effects jumping from Effexor to pristiq except shortness of breath and tight chest. Which mind you is not nice. And documents state I should tell my doc straight away. Well it's Easter weekend and he's not in so I'm just hanging on til tomorrow, til he's in again. I hope I just live with all the other stuff like the constant over sweating, no Lobido, constipation.
Updated 1 month ago.
Weaning off pristiq!!
12 Replies RSS
I have been on pristine for many years! My doc had said to go down to 50 mg for 3 weeks then none. I go in to see him in 3 more weeks- I am a mess!! Crying a lot and brain zaps (good term) from other messages. I hope to God this gets better soon. ## Hello, Sue! How are you doing? Yes, if you were on it for such a long time and abruptly stop taking it, then such rebound and withdrawals effects will usually occur. That was still a relatively high amount to have you stop on. Learn more Pristiq details here. The preferred method now is usually to do a very gradual taper, by slowly lowering the medication and starting to skip doses. Did he give a reason he was having you stop at 50mgs? He could have had you use the regular release formulation and just cut them to lower it further for awhile....
Updated 2 months ago.
Weight gain and depression AFTER getting off Pristiq
2 Replies RSS
I weaned myself off Pristiq over the summer and felt fine for a couple months. Then I gained 40 POUNDS in what couldn't have been more than two months. Waist grew 2 inches during that time. Now it's almost March and I've been more depressed over the last couple of months than ever in my life. I rarely have any energy and can't lose the weight. The reason I weaned myself off is because I mistakenly thought I didn't need it any more (the doctor who prescribed it said it "teaches" the brain how to produce whatever it does after a couple years and you don't need it any more). I'm going back on it and praying I feel like myself again - this is a miserable existence. Also, I haven't been able to find weight gain as a symptom of discontinuing Pristiq. ##...
Updated 2 months ago.

Possible Dosages for this and Related Drugs:

Desvenlafaxine Succinate
  • Tablet: 100mg, 50mg
  • Tablet, Extended Release: 100mg, 25mg, 50 Mg. And 100 Mg., 50mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Desvenlafaxine Succinate or a similar ingredient: (3 results)

Possibly related Pristiq Topics:

pristiq and weight gain I started pristiq approx 5 weeks ago and altho my doctor assured me that it was a weight neutral drug I have easily gain... 73 replies
Pristiq This is NOT a good medicine. I felt more depressed on it and had several side effects, nausea, lack of appetite, dizzine... 39 replies
pristiq for depression and anxiety did not work My Son went to the Dr. for anxiety and depression, pristiq created more problems for him, panic attacks, insomnia, loss ... 12 replies
pristiq withdrawl Hi all, I was on 150 of pristiq and have been tapering off for two months. Last week I went from 50 to 25 for about 4 da... 5 replies
Pristiq an Libido- Advice Needed! I have been taking Pristiq for about 3 years now due Anxiety attacks. After taking the drug for afew days I had the wors... 5 replies
Pristiq Withdrawls I have been on Pristiq for about 4 years and was on levoxyl for a few years prior. I had started taking Sarafem 925mg) a... 4 replies
Pristiq and hot flushes/flashes I have been on this for 5 days. The last 3 days I have been having hot flushes and they have been getting more frequent.... 4 replies
Pristiq - fatigue I have started taking pristiq about 6 weeks ago and I have noticed in the last week or so that I have been extremely fat... 4 replies
pristiq is it a narcotic is pristiq a narcotic I NEED TO KNOW ## Hello, Joe! How are you? No, Pristiq contains the active ingredient Desvenlafaxi... 3 replies
pristiq withdrawal I am going through menopause and my doctor switched me from Prestiq to Zoloft. The Prestiq wasn't helping the anxiet... 3 replies