Active Ingredient(s): Desvenlafaxine Succinate
FDA Approved: * February 29, 2008
Pharm Company: * WYETH PHARMS INC
Category: Antidepressant

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Pristiq Overview

Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.[1] It is an example of evergreening. Contents 1 Medical use...

Read more Pristiq Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Pristiq Forums: RSS Feed

Switched from Pristiq to Wellbutrin XL
36 Replies RSS
I'm adding a post to hopefully help someone as reading other people's posts has been very helpful/comforting to me! I have been on 50 mg of Pristiq for 5 years and I just made the transition to Wellbutrin xl at 300 mg. My doc switched me because my libido was becoming obsolete and wellbutrin is not supposed to adversely effect this. He had me start by overlapping the two meds for Week 1...Maintaining 50 mg of pristiq and adding Wellbutrin XL at 150 mg. I felt completely fine, didn't notice anything different. Week 2-I was to go up to 300 mg of Wellbutrin XL and completely stop taking the Pristiq. That didn't work. 1.5 days in I was dizzy, minor brain zap feeling (but not as intense as when i would miss a pristiq pill in the past) feeling super emotional (weepy) so much t...
Updated 8 minutes ago.
Starting Pristiq
1 Reply RSS
I've been pretty anxious my whole life. Used Paxil at 15 after a bad experience with drug my anxiety was insane. I then stopped using Paxil after a month and managed with my anxiety. I then had to use cipralex twice because my anxiety went crazy. But always stopped after 3 months. But for 3 years I have been using temazepam 30mg everyday. This pill helped me sleep at night however I didn't know I would end up being so addictive. I feel so happy at night when I take it. Now my anxiety is back and I went to see the doctor because I couldn't stand it... I go shopping and have major anxiety panic attack and feel like I will faint. So I went to see my doctor because first I wanted to stop temazepam and second to help with anxiety.. the thing is that since I started using ...
Updated 15 days ago.
Pristiq Side Effects after being on for years
1 Reply RSS
I have been on pristiq 100mg for about 10 years now for depression and anxiety it has been working for many years but today I feel terrible with head spins, nausea and systems i usually get when i forget a pill which i haven't is there any reason for this? ## Hello, Danielle! How are you? After 10 years, it may be that your body has just grown tolerant to this dosage, which could explain why you're feeling some withdrawal effects, as if you missed a pill. The U.S. FDA lists other as possibly including rebound depression, anxiety, chills, and diarrhea. It may be time for a dosage adjustment, or you may need to try an entirely different medication. Is there anything else I can help with?
Updated 15 days ago.
Pristiq Night Sweats
5 Replies RSS
Hi all, I have been on Pristiq for 5+ years. Soon after I began, I started dealing with night sweats. Not just mild sweat - I'm talking my PJs and sheets are drenched. It is awful! The night sweats have come and go over the years but are currently very bad. I can't seem to get much information on the internet about this side effect being an issue for many people. Has anyone else experienced night sweats from taking Pristiq? ## Hi Erin, According to the manufacturer, sweating is actually one of the most common side effects people experience from taking Pristiq (Desvenlafaxine). However, happens to list "sweating" as both a 'general' and 'serious' side effect here: Have you already made your doctor ...
Updated 20 days ago.
Pristiq comming off it
1 Reply RSS
Hi, there, was taking Pristiq for 2 yrs 50mg, was good but very big weight gain. So i decided to come off it. Not too bad. For 5 days i cut tablet in half, for 5 days went to quarter, then stopped. Had a little stomach cramping for a day or so, my head felt a little wobbly at times while on quarter, only down fall is really bad dreams. Been free from Pristiq for about 1 week now and all is well. ## I am about to go to a 1/4 tablet plz keep me posted on how you are going good luck thanks
Updated 22 days ago.
Weight gain on Pristiq??
550 Replies RSS
I have been on Pristiq now since November of 2008...not quite 5 months...and I have put on 15 lbs since starting it. DESPITE working out with a trainer at the gym twice a week weight training, 3 days a week of cardio AND counting calories. My doc assured me that I would also have a decreased appetite on Pristiq, which I have yet to find he has now increased my dosage to 400 mg. Does anyone have anything to add to this?? I'm just frustrated! ## i was switched to pristiq a few months ago and just recently wellbutrin was added - i take 1 of each pill per day - it has done nothing to me in gaining weight - i am continuously losing but i have some emtional things going on right now which i believe the weight loss is contributed too - unfortunately i have run into many that have...
Updated 26 days ago.
1 Reply RSS
Are Pristiq and Wellbutrin in the same category? ## No I have been on 100 mg of Pristiq for 2 years. Pristiq is for Seritonin. Wellbutrin is for Dopamine. Some of us who are bipolar, our bodies do not make enough of either. Pristiq is for my Seritonin which helps with sleep. Will start Wellbutrin XR 150mg tablets on September 2nd. Dopamine makes a person happy. you laugh more, enjoy life more and all that. All this was explained to me by my neurologist and psychiatrist.
Updated 1 month ago.
Took my Pristiq twice - how bad is that?
1 Reply RSS
I've been on Pristiq 100mg for 8 years with great success. tongiht -for the first time in all that time, I accidentally took a second pill. Do I need to be worried? ## Hello, Alda! How are you? Usually, there isn't much danger from doing this occasionally, we all have our forgetful moments. The real danger would be if you did all the time, or took way more and overdosed. However, it is always best to inform your doctor, just in case. The FDA lists the warning signs of an overdose as possibly including nausea, severe dizziness, drowsiness, sedation, and vomiting. Is there anything else I can help with?
Updated 1 month ago.
Weaning off pristiq
416 Replies RSS
I just wanted to tell all of you trying to get off pristiq, its possible. I was on pristiq for severe panic attacks for 6 months. It saved my life. It gave me a chance to slow down my career, gave me a huge wakeup call. This drug put a cloud over my brain. I was not my happy, fun loving self. I was like a step ford wife. You cant wean off this pill. I was on 50mg. I did every other day for a month. Every third day for two weeks then cold turkey. It really was not so bad. I layer on my couch for three days, cried a bit and watched movies. I'm happily on all holistic medications, no longer a slave to pristiq. If I can beat anxiety, anyone can. My biggest advice.. Exercise. Next, surround yourself with positive people. Three, talk out your problems. Good luck. ## Fantastic advice and v...
Updated 2 months ago.
41 Replies RSS
This is NOT a good medicine. I felt more depressed on it and had several side effects, nausea, lack of appetite, dizziness, etc. Then, after being on it for 2 weeks, I had a severe allergic reaction to it. So not fun! No more Pristiq for me. Throw the stuff away! ## I went on Pristiq for 10 days - had shortness of breath, and all the other side side effects. Dr. office told me to stop 'cold turkey' - It's been 7 daysoff and I am still not feeling normal! What's up with that?? They told me it would only be a couple of days. So I call them and tell them I am still having withdrawal symptoms - they act like I am crazy! And it must be something else wrong with me! I have NEVER felt like this - until taking pristiq! When will it end? My advice - dont even start the stuff! But...
Updated 3 months ago.

Possible Dosages for this and Related Drugs:

Desvenlafaxine Succinate
  • Tablet: 100mg, 50mg
  • Tablet, Extended Release: 100mg, 25mg, 50 Mg. And 100 Mg., 50mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Pristiq: (6 results)

Sorted by National Drug Code
  • 0008-1211 24 Hr Pristiq 50 mg Extended Release Tablet by Wyeth Pharmaceuticals Inc., a Subsidiary of Pfizer Inc.
  • 0008-1222 24 Hr Pristiq 100 mg Extended Release Tablet by Wyeth Pharmaceuticals Inc., a Subsidiary of Pfizer Inc.
  • 35356-491 24 Hr Pristiq 50 mg Extended Release Tablet by Lake Erie Medical & Surgical Supply Dba Quality Care Products LLC
  • 35356-567 24 Hr Pristiq 100 mg Extended Release Tablet by Lake Erie Medical Dba Quality Care Products LLC
  • 54868-2932 24 Hr Pristiq 50 mg Extended Release Tablet by Physicians Total Care, Inc.
  • 55154-4230 24 Hr Pristiq 50 mg Extended Release Tablet by Cardinal Health

Other drugs which contain Desvenlafaxine Succinate or a similar ingredient: (3 results)

Possibly related Pristiq Topics:

pristiq and weight gain I started pristiq approx 5 weeks ago and altho my doctor assured me that it was a weight neutral drug I have easily gain... 74 replies
Pristiq This is NOT a good medicine. I felt more depressed on it and had several side effects, nausea, lack of appetite, dizzine... 41 replies
pristiq for depression and anxiety did not work My Son went to the Dr. for anxiety and depression, pristiq created more problems for him, panic attacks, insomnia, loss ... 13 replies
Pristiq Night Sweats Hi all, I have been on Pristiq for 5+ years. Soon after I began, I started dealing with night sweats. Not just mild swea... 5 replies
pristiq is it a narcotic is pristiq a narcotic I NEED TO KNOW ## Hello, Joe! How are you? No, Pristiq contains the active ingredient Desvenlafaxi... 5 replies
pristiq withdrawl Hi all, I was on 150 of pristiq and have been tapering off for two months. Last week I went from 50 to 25 for about 4 da... 5 replies
Pristiq an Libido- Advice Needed! I have been taking Pristiq for about 3 years now due Anxiety attacks. After taking the drug for afew days I had the wors... 5 replies
Pristiq Withdrawls I have been on Pristiq for about 4 years and was on levoxyl for a few years prior. I had started taking Sarafem 925mg) a... 4 replies
Pristiq and hot flushes/flashes I have been on this for 5 days. The last 3 days I have been having hot flushes and they have been getting more frequent.... 4 replies
Pristiq - fatigue I have started taking pristiq about 6 weeks ago and I have noticed in the last week or so that I have been extremely fat... 4 replies