Active Ingredient(s): Desvenlafaxine Succinate
FDA Approved: * February 29, 2008
Pharm Company: * WYETH PHARMS INC
Category: Antidepressant

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Pristiq Overview

Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.[1] Contents 1 Medical uses 2 Adverse effects 3 Pharmacology...

Read more Pristiq Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Pristiq Forums: RSS Feed

Beginning Pristiq and nausea
2 Replies RSS
I just started Pristiq today. I have depression and panic attacks several times a week. I was previously on Lexapro and Lamictil. I felt The Lamictal induced the panic attacks. My doc changes me to Effexor 160mg. My HR went through the roof, nausea, shakiness. My doc switched me to Pristiq. I feel so nauseated. How long will this last? I cannot wait this out for weeks! I have a life: a family, a job! I've seen mainly bad reviews for this medicine! Feeling frustrated! ## Hey Mama, I was on lexapro too and switched to pristiq. I am currently on day 36 of pristig 50 mg and the nausea went away after about a week. So with that part it'll get better. I too have bad anxiety and actually puke from anxiety but I have yet to puke on pristiq. Anxiety wise i don't know if it's help...
Updated 9 minutes ago.
Pristiq agitated
1 Reply RSS
Been on pristiq 6-7 weeks on mg. I notice I've been getting better but I'm a lot more angry and agitated. I recently quit lexapro but my dr said that is just me getting angry, I'm concerned if it's the drug or me? Anyone know if pristiq can make you angry ## Hello, Chris 51! How are you? That can be a normal side effect for the first few weeks, when you take such a medication, especially coupled with the withdrawal effects of stopping the Lexapro. It usually takes about 3 to 4 weeks for things to improve. Other side effects, as listed by the FDA, may possibly include nausea, dizziness, dry mouth and weight changes. Is there anything else I can help with?
Updated 1 day ago.
127 Replies RSS
atrial fibrillation ## Pristiq, which contains the active ingredient Desvenlafaxine, is an antidepressant. Some of the most common side effects include: nausea, drowsiness, sexual dysfunction and constipation. ## For 18 years I have been taking Prozac. Each time I have attempted to change, under the care of a physician, I've touched the bottom of depression again. During the last several years my dosage has been upped to 40 mg in the AM and 40 in the PM. I've suffered anxiety, expecially upon awakening in the morning. In the last 10 years I've been divorced from a man with passive-aggressive tendancies. I go to a well reputed psychologist,exercise and eat well. I regularly meditate and do daily journaling,etc. I'm now married to a good person. My psychologist, chiropract...
Updated 1 day ago.
Weight loss? No appetite
Post a Reply
I've suffered from anorexia in the past and have severe anxiety. After taking the genomind test I can only take a few medications like pristiq. I've lost 6 pounds so far on pristiq during the last 3 months and can't afford to lose anymore. I thought antidepressants were supposed to help give me my appetite back again and not worry about food. Should I ask to switch to something that will make me more hungry?
Updated 3 days ago.
Weight gain on Pristiq??
541 Replies RSS
I have been on Pristiq now since November of 2008...not quite 5 months...and I have put on 15 lbs since starting it. DESPITE working out with a trainer at the gym twice a week weight training, 3 days a week of cardio AND counting calories. My doc assured me that I would also have a decreased appetite on Pristiq, which I have yet to find he has now increased my dosage to 400 mg. Does anyone have anything to add to this?? I'm just frustrated! ## i was switched to pristiq a few months ago and just recently wellbutrin was added - i take 1 of each pill per day - it has done nothing to me in gaining weight - i am continuously losing but i have some emtional things going on right now which i believe the weight loss is contributed too - unfortunately i have run into many that have...
Updated 8 days ago.
3rd week pristiq
1 Reply RSS
3rd week on pristiq and I'm still getting anxious and puking because of my anxiety. Should I give the 50 mg more time or ask for another solution? ## Hello, Lola84! How are you? It can take 4 to 5 weeks, before this medication reaches its full level of effectiveness in your body, it can also cause some increased anxiety, for awhile, while you're body is getting used to it. Thus, it may be best to give it a couple more weeks to see if things settle down and it helps you, unless your doctor feels otherwise. The FDA lists its other typical side effects as possibly including dizziness, headache, dry mouth, mood swings and weight changes. Is there anything else I can help with?
Updated 12 days ago.
Weaning pristiq
2 Replies RSS
Hi, I am a female 44 years old, started taking pristiq about 4 1/2 years ago, decided to wean off at the beginning of December 2015, way... Too many side effects and body pains and weight gain. It's not easy but it's doable , I am on week 3 of 0 pristiq and my brain zaps and ringing in my ears have come to an end Thank God. Now I am dealing with the sadness and the irritability part which have been there all along but are more frequent now, I can't tell you when it's going to be manageable but I can tell you that it will get better because I believe it is! I have suicidal thoughts even when I was taking pristiq but I have to say they have gotten a bit better, the sadness is what overwhelms me sometimes. I will keep you posted about the weight loss which is a huge concern...
Updated 12 days ago.
anxiety worse on pristiq
5 Replies RSS
6 months ago my doctor switched me to Pristiq xr 100mg to replace Effexor xr 75mg. The med. always seems to stop working after abot 6 or7 months or so. I have not seen my doc in 6 months and i've noticed my anxiey is terrible. I don't trust co-workers and am paronoid that when I walk into work, they are thinking bad thoughts of me. This stops me from opening up/making friends. My co-workers eventually end up not liking me. I hope someone can relate with me. 5 years ago this was just depression, and the in the last 3 years whatever anxiety I may have had has slowly gotten worse. Is this typical of these medications? I've even considered divorcing just to start a new life/new chapter. I hope someone can help. thank you. ## My wife of 13 years started acting irrational, had ras...
Updated 23 days ago.
pristiq for depression and anxiety did not work
13 Replies RSS
My Son went to the Dr. for anxiety and depression, pristiq created more problems for him, panic attacks, insomnia, loss of appetite and he had black outs, got into some legal trouble and says he does not remember anything about that night. Anyone else had this type of problem? ## I was first prescribed 50 mg and now have been raised to 100 mg of Pristiq a day and 60 mg of Buspar for anxiety and depression. I have noticed that I have been getting irritated and grouchy more often while on the medicine. I have been on for about 3 months now and have set up an appointment to discuss this with my doctor. Not happy at all with this combination. I also had a loss in appetite, but no blackouts. ## had a severe seizure while on pristiq, had been taking the medication for about a year. I was gett...
Updated 26 days ago.
Pristiq dose increase. Really need advice!
2 Replies RSS
I have depressive disorder and generalized anxiety disorder, and am currently taking Pristiq 50mg once daily, along with Buspar 10mg twice daily. I was taking 300mg Wellbutrin XL with that, but my psych dr thought it my be exacerbating my anxiety. A few weeks ago she decreased my Wellbutrin dosage to 150mg and changed it to the SR formula. Now she wants me to quit the Wellbutrin completely and up my Pristiq.. I I have been on 50mg Pristiq once daily for almost a year now, and I don't really think it's been working for me for some time. When I first started taking it, I switched from Zoloft 100mg and found my mood improved quickly. After a while I think I went more towards either being depressed or apathetic, but yet couldn't actually recognize until my husband told me that I...
Updated 27 days ago.

Possible Dosages for this and Related Drugs:

Desvenlafaxine Succinate
  • Tablet: 100mg, 50mg
  • Tablet, Extended Release: 100mg, 25mg, 50 Mg. And 100 Mg., 50mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Pristiq: (6 results)

Sorted by National Drug Code
  • 0008-1211 24 Hr Pristiq 50 mg Extended Release Tablet by Wyeth Pharmaceuticals Inc., a Subsidiary of Pfizer Inc.
  • 0008-1222 24 Hr Pristiq 100 mg Extended Release Tablet by Wyeth Pharmaceuticals Inc., a Subsidiary of Pfizer Inc.
  • 35356-491 24 Hr Pristiq 50 mg Extended Release Tablet by Lake Erie Medical & Surgical Supply Dba Quality Care Products LLC
  • 35356-567 24 Hr Pristiq 100 mg Extended Release Tablet by Lake Erie Medical Dba Quality Care Products LLC
  • 54868-2932 24 Hr Pristiq 50 mg Extended Release Tablet by Physicians Total Care, Inc.
  • 55154-4230 24 Hr Pristiq 50 mg Extended Release Tablet by Cardinal Health

Other drugs which contain Desvenlafaxine Succinate or a similar ingredient: (3 results)

Possibly related Pristiq Topics:

pristiq and weight gain I started pristiq approx 5 weeks ago and altho my doctor assured me that it was a weight neutral drug I have easily gain... 73 replies
Pristiq This is NOT a good medicine. I felt more depressed on it and had several side effects, nausea, lack of appetite, dizzine... 40 replies
pristiq for depression and anxiety did not work My Son went to the Dr. for anxiety and depression, pristiq created more problems for him, panic attacks, insomnia, loss ... 13 replies
pristiq is it a narcotic is pristiq a narcotic I NEED TO KNOW ## Hello, Joe! How are you? No, Pristiq contains the active ingredient Desvenlafaxi... 5 replies
pristiq withdrawl Hi all, I was on 150 of pristiq and have been tapering off for two months. Last week I went from 50 to 25 for about 4 da... 5 replies
Pristiq an Libido- Advice Needed! I have been taking Pristiq for about 3 years now due Anxiety attacks. After taking the drug for afew days I had the wors... 5 replies
Pristiq Withdrawls I have been on Pristiq for about 4 years and was on levoxyl for a few years prior. I had started taking Sarafem 925mg) a... 4 replies
Pristiq and hot flushes/flashes I have been on this for 5 days. The last 3 days I have been having hot flushes and they have been getting more frequent.... 4 replies
Pristiq - fatigue I have started taking pristiq about 6 weeks ago and I have noticed in the last week or so that I have been extremely fat... 4 replies
pristiq withdrawal I am going through menopause and my doctor switched me from Prestiq to Zoloft. The Prestiq wasn't helping the anxiet... 3 replies