Active Ingredient(s): Desvenlafaxine Succinate
FDA Approved: February 29, 2008
Category: Antidepressant

Pristiq Overview

Desvenlafaxine (brand name: Pristiq, DESFAX), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.[1] Contents 1 Medical uses 2 Adverse effects 3 Pharmacology...

Read more Pristiq Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Pristiq Forums: RSS Feed

Weaning off pristiq
379 Replies RSS
I just wanted to tell all of you trying to get off pristiq, its possible. I was on pristiq for severe panic attacks for 6 months. It saved my life. It gave me a chance to slow down my career, gave me a huge wakeup call. This drug put a cloud over my brain. I was not my happy, fun loving self. I was like a step ford wife. You cant wean off this pill. I was on 50mg. I did every other day for a month. Every third day for two weeks then cold turkey. It really was not so bad. I layer on my couch for three days, cried a bit and watched movies. I'm happily on all holistic medications, no longer a slave to pristiq. If I can beat anxiety, anyone can. My biggest advice.. Exercise. Next, surround yourself with positive people. Three, talk out your problems. Good luck. ## Fantastic advice and v...
Updated 8 seconds ago.
about my pristiq
1 Reply RSS
I ran out of my pristiq and could not see my doctors for a repeat so now im back on it with a few side affects. ## Hello, Katrina! How are you? Yes, if you weren't taking it for awhile, then started again, it is normal to experience side effects, again. The FDA lists the typical side effects of Pristiq as possibly including nausea, dizziness, headache, weight changes, dry mouth and mood swings. Is there anything else I can help with?
Updated 1 day ago.
Accidently took double dose of pristiq for 3 days
1 Reply RSS
I am new to taking pristiq and have been taking 100mg for around 3 weeks. Initially my script was for 50mg so I was taking 2. When I got my next script filled I didn't realise they were 100 mg tablets and I accidently took 2 each day for 3 days before I realised they were 100mg, so for 3 days I have taken 200mg rather than 100mg and now I know why I was feeling extremely nauseous and dizzy. I have now just continued taking the 100mg as per normal but am feeling very strange, agitated and dizzy. Has anybody done this before? Should the symptoms settle quickly? ## Hello, Dani! How are you? Yes, the symptoms should settle down, but it may take a week or two. Typical side effects, as listed by the FDA, may include nausea, dizziness, headache, dry mouth and weight changes. If they don...
Updated 1 day ago.
Pristiq dose increase. Really need advice!
1 Reply RSS
I have depressive disorder and generalized anxiety disorder, and am currently taking Pristiq 50mg once daily, along with Buspar 10mg twice daily. I was taking 300mg Wellbutrin XL with that, but my psych dr thought it my be exacerbating my anxiety. A few weeks ago she decreased my Wellbutrin dosage to 150mg and changed it to the SR formula. Now she wants me to quit the Wellbutrin completely and up my Pristiq.. I I have been on 50mg Pristiq once daily for almost a year now, and I don't really think it's been working for me for some time. When I first started taking it, I switched from Zoloft 100mg and found my mood improved quickly. After a while I think I went more towards either being depressed or apathetic, but yet couldn't actually recognize until my husband told me that I...
Updated 1 day ago.
How to combat Pristiq drowsiness one month in?
1 Reply RSS
Ok, I would like to hear back from anyone who is successfully taking Pristiq...I just did an ID Genetix test through my doctor and it tested for depression first with anxiety as my backup issue. It gave me results on which medications I can successfully take to treat these issues according to my genetic makeup. Kind of a lifesaver after years of fooling around with different meds, different doses and docs who really had no idea what to do for me. So, Pristiq came back as my best choice to treat my main issue - Depression. I started taking 50mg daily on 6/28/15. Took it at bedtime since that's when I was taking my previous med, just thought I would try that first since there was really no indication other than to take at the same time each day. About two weeks ago, the drowsiness dur...
Updated 7 days ago.
prestique medication
6 Replies RSS
my dr wants to put me on prestique to help with stress and to help my sex drive ## Pristiq contains the active ingredient Desvenlafaxine, it is an SNRI antidepressant. Common side effects may include: nausea, drowsiness, weight gain and dry mouth. You can read more on it here: Sometimes these medications make people suffer from problems with their sex drives, so you should be aware of that. Is there anything else I can help you with? ## I have tried lexapro, prozac, and celexa without much help. I need an anti-depressant that does not negatively affect my sex drive. I feel like i have no sex drive due to meds. I need a an anti-depressant that improves my sex drive. Im 24 I should be thriving. Help. ## my doctor wanted to put me on pristique for depression. he gave me some samples to try...
Updated 29 days ago.
126 Replies RSS
atrial fibrillation ## Pristiq, which contains the active ingredient Desvenlafaxine, is an antidepressant. Some of the most common side effects include: nausea, drowsiness, sexual dysfunction and constipation. ## For 18 years I have been taking Prozac. Each time I have attempted to change, under the care of a physician, I've touched the bottom of depression again. During the last several years my dosage has been upped to 40 mg in the AM and 40 in the PM. I've suffered anxiety, expecially upon awakening in the morning. In the last 10 years I've been divorced from a man with passive-aggressive tendancies. I go to a well reputed psychologist,exercise and eat well. I regularly meditate and do daily journaling,etc. I'm now married to a good person. My psychologist, chiropract...
Updated 29 days ago.
Coming off Pristiq
4 Replies RSS
Wanted to share my experience with coming of this drug with others because I have looked towards others experiences the past few days which have helped me a ton! I started taking Lexpro around the age of 17 never had any real issues besides being tired a lot. I stayed on Lexpro for over 3 years. After complaining about being tired my doctor wanted me to try Pristiq saying it might give me more energy. The switch over between Lexpro and Pristiq was easy I don't recall any struggles. Now I have been taking Pristiq for about 3 years. I have always taken 50mg once a day. If I followed that dosage I was totally fine. But if for whatever reason I missed a day I was shortly reminded by the terrible dizziness an nausea. About a year ago I told the same doctor that put me the medication I wa...
Updated 30 days ago.
Pregnant on pristiq
1 Reply RSS
Are there any women out there whom have become pregnant while on pristiq and continued use during the pregnancy? I just found out I was pregnant and the dr wants me to continue taking it. I am scared of birth defects and would like to hear others stories. Please Ty Jo ## Hello, Jo! How are you? Congrats on the baby!! The FDA does list this medication as being in category C, which means risk has not been ruled out, but conversely, that means that it also hasn't been known to definitively cause any problems in people. Its typical side effects may possibly include nausea, dizziness, headache, dry mouth, mood swings and weight changes. Can anyone that's taken it while pregnant chime in?
Updated 1 month ago.
Pristiq refill feel different?
1 Reply RSS
Each time Walmart refillsy 100mg Pristiq prescription, I feel side effects as if being started in a new medication. Anyone else have this unusual problem? ## Hello, Jeb! How are you? It is rare, but some people always experience some medication side effects, just due to their own body chemistry. However, are you receiving pills each time from different manufacturers, or have they been the same? Are you making sure not to run out, before picking up a refill? The FDA classifies Pristiq as an SNRI antidepressant and lists its typical side effects as possibly including nausea, dizziness, headache, dry mouth, mood swings and weight changes.
Updated 1 month ago.

Possible Dosages for this and Related Drugs:

Desvenlafaxine Succinate
  • Tablet: 100mg, 50mg
  • Tablet, Extended Release: 100mg, 25mg, 50 Mg. And 100 Mg., 50mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Desvenlafaxine Succinate or a similar ingredient: (3 results)

Possibly related Pristiq Topics:

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pristiq withdrawl Hi all, I was on 150 of pristiq and have been tapering off for two months. Last week I went from 50 to 25 for about 4 da... 5 replies
Pristiq an Libido- Advice Needed! I have been taking Pristiq for about 3 years now due Anxiety attacks. After taking the drug for afew days I had the wors... 5 replies
Pristiq Withdrawls I have been on Pristiq for about 4 years and was on levoxyl for a few years prior. I had started taking Sarafem 925mg) a... 4 replies
Pristiq and hot flushes/flashes I have been on this for 5 days. The last 3 days I have been having hot flushes and they have been getting more frequent.... 4 replies
Pristiq - fatigue I have started taking pristiq about 6 weeks ago and I have noticed in the last week or so that I have been extremely fat... 4 replies
pristiq is it a narcotic is pristiq a narcotic I NEED TO KNOW ## Hello, Joe! How are you? No, Pristiq contains the active ingredient Desvenlafaxi... 3 replies
pristiq withdrawal I am going through menopause and my doctor switched me from Prestiq to Zoloft. The Prestiq wasn't helping the anxiet... 3 replies