Difference Between 5/325 And 5/325 Apap
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I was prescribed hydrocodone 5/325 APAP and now I'm prescribed 5/325. No APAP on the bottle. It seems it's not as strong. Is there difference ?

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@Viking,

BL is correct, there is no difference in the name. However the difference in strength that you're noticing could very well be attributed to the different set of inactive ingredients used in each manufacturer's version of this medication; since they have been proven to affect overall bioavailability.

Additionally, when it comes to generic meds (such as this one), rumor has it that the FDA permits manufacturers to have a leeway of plus or minus 20% in peak plasma concentrations, compared to brand names. This may mean that there are only 4 active milligrams out of a 5mg dose of Hydrocodone when it's working at its peak. Has anyone else found evidence that this is true?

I hope this helps!

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There is no difference. Apap is short for Acetaminophen .

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