Azathioprine Safety
UpdatedHello. I take this medication for colitis as told by my doctor it's safe. Now after reading the notes about this on here i am scared. I've being taking this for 3 weeks now (2 per day) - Am i safe?
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I was suspected to have some auto-immune disease like - Scleroderma, MCTD, Dermatomysositis or Eosonophilic faciitis. All immunological tests parameters had turned out negative including RA factor done repeatedly in advance method in last one half years. ANA/ANF is -ve done several times in different labs. Doctors treated me with Pulse Mythyle Prednisolone IV 1 g each for 5 days and I was admitted in a specialized hospitals for 22 days. I had suffered from whole body itching, pain, mouth ulcer, swallowing difficulty, movement difficulty, swelling of face & limbs, pain in abdomen and no medicine could give me any relief. in 2 months. After Pulse Steroid IV Inj I was relieved immediately. There-after I was given Oral Prednisolne Tab and Azathioprine Tab. Reducing gradually the dose of Prednisolne Tab it stopped in October last. Azathioprine first 50 mg OD and after 4 months 50mg BD. Blood Tests of Complete Blood Count, LFT, Kidney function were being done every month. Recently it is seen that the WBC is low 3.14 and 3.89. Doctors had stopped Azathiprine for 15 days. WBC became 6.31. Azathioprine Tad restarted, found again WBC is 3.74. Again Azathioprine has been stopped. Other medicines are contnuing for Calcium. Vit D Thyroid etc. I have now only shoulder joint pain. Doctors are thinking for other nature/mode of treatment i.e. MMF. I do not understand. I do not want to take other medicine except Prednisolone Tab and/or Azathioprine Tab. I was doing well for last about one and half years. I had come out of very dangerous condition for about 2 months in August 2014 to September 2014. I got relief by Pulse Steroid therapy and then immuno-suppressants Tab Steroid/Non-steroid. But still now nothing has been diagnosed. According to the doctors I do not have any symptoms or disease activity of any auto-immune diseases. Please advise me what to do now.
It is best to take the medication as directed by your doctor. All medications carry the risk of causing side effects, that is just the nature of adding a chemical to the body to help prevent, or correct a problem.
The NIH lists the typical ones for this medication as possibly including nausea, dizziness, headache, diarrhea, and stomach pain.
How are you both doing, now? Has there been any change? Are you on any other medications?
I have auto immune hep. I have been on azaphioprine for 18 months, but for the last 5 months I have had muscle weakness & cramps in my legs & fingers. I also get pins & needles in them. Can azathioprine be causing this?
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