Hismanal

Astemizole

Astemizole (marketed under the brand name Hismanal, developmental code R43512) was a second-generation antihistamine drug that has a long duration of action. Astemizole was discovered by Janssen Pharmaceutica in 1977. It was withdrawn from the market globally in 1999 because of rare but potentially fatal side effects (QTc interval prolongation and related arrhythmias due to hERG channel blockade).[2][3] Contents 1 Pharmacology 2 Toxicity 3 References 4 Extern...

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Astemizole (marketed under the brand name Hismanal, developmental code R43512) was a second-generation antihistamine drug that has a long duration of action. Astemizole was discovered by Janssen Pharmaceutica in 1977. It was withdrawn from the market globally in 1999 because of rare but potentially fatal side effects (QTc interval prolongation and related arrhythmias due to hERG channel blockade).[2][3] Contents 1 Pharmacology 2 Toxicity 3 References 4 Extern...

When I get hives the best medicine is Hisminal. zyrtec sucks and the other ones don't work that well either. Is there anything out there close to hisminal or will the manufactures ever bring it back? ## I agree -- there is nothing that has worked as well for me as Hisminal did. I second that question -- Is there anything out there close to hisminal or will the manufacturers ever bring it back? Is it still on the market in other countries? ## Hismanal, which contained the active ingredient Astemizole was withdrawn from the global market in 1999 due to rare, but potentially fatal side effects, and the discovery of newer antihistamines that are safer to use. You can learn more about Hismanal Market Withdrawal. The basic reason was that is was found to sometimes cause fatal cardiac arrh...

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small round tabs says janssenon one side ast 10 on other ## Hismanal/Astemizole Info Click Here

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