Apotex Vs Pliva Trazodone

apotex vs pliva trazodone

My pharmacy just switched manufacturers of my prescription trazodone 50mg. It used to be made by apotex now it is pliva and I am finding that the new pills are having little to no effect and I am starting to suffer discontinuation syndrome. I talked to my pharmacist and doctor and neither one could tell me what was causing this. I was just wondering if there is anyone out there who could shed some light on the subject. ## Yes, I can. Under Federal Law, by way of the Hatch Watchman Act of 1984, generics are allowed to differ from their name brand counterparts by as much as plus or minus 20% in the active ingredient. Many people are not aware of this, including doctors, but the FDA considers this to be a very minor difference that does not affect the therapeutic dosing of medications. So,...

103 REPLIES Filed under Trazodone

APO vs. PLI??

When I refilled my perscription for Trazadone, I though the pills looked different. they are small white round pills with a split line and PLIVA 433 stamped on them. The old ones were oval I think. The old bottle says Trazodone 50 mg Tablet APO. The new one says Trazodone 50 mg Tablet PLI What is the difference? ## Only the manufacturer! PLI on the new pills stands for Pliva Pharmaceuticals and the other ones were made by Apotex. Most pharmacies will switch according to whomever provides the cheapest option when they have to reorder. The medication, however, is the same. Do you have any other questions? ## There IS a difference! I have experienced tachcardia every night since switching from Apo to Pli. I am not happy! ## I have also felt jittery and had more problems sleeping on the pli...

6 REPLIES Filed under Trazodone