Relistor

Methylnaltrexone Bromide

Methylnaltrexone (MNTX, brand name Relistor), used in form of methylnaltrexone bromide (INN, USAN, BAN), is a medication that acts as a peripherally acting μ-opioid receptor antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without significantly affecting pain relief or precipitating withdrawals. Because MNTX is a quaternary ammonium cation, it cannot cross the blood–brain barrier, and so has antagonist effects throughout the body, counte...

I would like some feedback on Relistor 150 mg. I've been prescribed 3 pills every morning for opioid-induced or severe constipation. I am actually a bit nervous about starting it. Any info or feedback would be great! ## Hello, Janet! How are you? This medication is used to treat opiate induced constipation. The FDA lists the typical side effects as possibly including nausea, diarrhea, headache, and dry mouth. What specifically makes you nervous about taking it? If you provide more details others might be able to address such issues for you. Can you please post back and clarify?

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Drug Index

Methylnaltrexone (MNTX, brand name Relistor), used in form of methylnaltrexone bromide (INN, USAN, BAN), is a medication that acts as a peripherally acting μ-opioid receptor antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without significantly affecting pain relief or precipitating withdrawals. Because MNTX is a quaternary ammonium cation, it cannot cross the blood–brain barrier, and so has antagonist effects throughout the body, counte...

Drug Index

Methylnaltrexone (MNTX, brand name Relistor), used in form of methylnaltrexone bromide (INN, USAN, BAN), is a medication that acts as a peripherally acting μ-opioid receptor antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without significantly affecting pain relief or precipitating withdrawals. Because MNTX is a quaternary ammonium cation, it cannot cross the blood–brain barrier, and so has antagonist effects throughout the body, counte...

I have been suddenly taken off of movantik because my insurance no longer covers it. I took it for OIC, it worked very well. This past week I’ve had to go without it and and I have experienced bloating, anxiety, sweats. Also I can't go to the bathroom no matter what I take in its place. Has anyone experienced anything like this? ## What else have you tried? It's kind of hard to make any suggestions, without knowing more details. There is another option available called Relistor, but since it is a name brand, your insurance may not cover it, either. Ref: Resistor Information When I was on opiates for pain, I had luck with just increasing my fiber intake using a fiber supplement. What does your normal diet consist of? Do you take in lots of leafy greens, and whole grains? ##...

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There is a pill out for constipation caused by opioids. I need it found out. There also is a medical term given to this condition. It's new and I saw it on tv earlier this month. But I can't remember what it was called. I need it so I can tell my doctor to prescribe me the medicine for my constipation caused by the opioids that I take for pain from him. Can you help me? ## Hello, April! How are you? Opioid Induced Constipation. The name of one of the medications is Relistor. The FDA lists its typical side effects as possibly including nausea, dizziness, abdominal pain, diarrhea and tremors. Is there anything else I can help with? ## Mpathia RI: Newest opioid induced constipation med is Movantik, Relister and one other. The bad news is you pay $200.00 at the very least with every...

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I have cancer in bones, kidney and liver, I started the patch 11 months ago but was never told how strong it was, my worst side effect has been chronic constipation.I am now on 12:5mcg per hour. And in Order to start my new chemo I need to get my constipation under control.tried to go off 25 patch in dec2013 for 11 days but was just miserable.needed patch at first because of 2 broken vertebra and rib,because of cancer. cannot have bowel movement on my own any more even with 5 laxatives including CREEPY relistor inj's. and miralax 2 times a day and stool softener. I regret fentanyl totally. ## Hello, Bob! How are you? Have you tried using fiber supplements? When I had a similar issue, while on pain management, I found that taking fiber supplements worked better than anything else to ...

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Does anyone know if there is a pill form of this drug? I am on alot of meds that cause constipation and this sounds like it would help me, but i've only seen it listed as an injectable medication.

If you too are testing positive for hydromorphone but are taking only other opioid medicines (and that includes peripheral antagonists, such as Movantik or Relistor, as well as drugs such as oxycodone or oxymorphone): Please respond with what opioid(s) you are taking, and also if you are taking any probiotics, what bacteria strains are listed on the package? (certain bacteria are known to transform some opioids to hydromorphone) Was a GCMS test done? I'll keep a tally and post the results, hopefully helping everyone with this problem. ## This is just an update: I stopped taking both the probiotics and Movantik, and had another GCMS urine test, which was (finally!) negative for hydromorphone. So, this shows that either Movantik or the probiotics were the cause of the unexpected resul...

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NDC Database

Relistor 150 mg Oral Tablet by Salix Pharmaceuticals, Inc. ## Markings: REL;PLAIN ## Shape: Round ## Color: White ## Package Codes: 65649-150-06, 65649-150-60, 65649-150-90 ## Active Ingredients: Methylnaltrexone Bromide

NDC Database

Relistor 12 mg/.6ml Subcutaneous Injection, Solution by Salix Pharmaceuticals, Inc. ## Package Codes: 65649-551-02, 65649-551-03, 65649-551-06, 65649-551-07 ## Active Ingredients: Methylnaltrexone Bromide

NDC Database

Relistor 8 mg/.4ml Subcutaneous Injection, Solution by Salix Pharmaceuticals, Inc. ## Package Codes: 65649-552-04 ## Active Ingredients: Methylnaltrexone Bromide

NDC Database

Relistor Kit by Salix Pharmaceuticals, Inc. ## Package Codes: 65649-553-05 ## Active Ingredients: Methylnaltrexone Bromide