Megestrol

Drug Index

Megestrol (INN, BAN) is a progestin of the 17α-hydroxyprogesterone group which was never marketed and is not currently used clinically.[1][2] Its acylated derivative megestrol acetate is also a progestogen, which, in contrast to megestrol itself, has been extensively used as a pharmaceutical drug.[1][2] Synthesis Megestrol synthesis:[3] U.S. Patent 2,891,079 See also Megestrol acetate Medroxyprogestero...

Looking for side effects and how to ease side effects ## Megestrol is used to treat advanced carcinoma of the breast and endometrium, in some cases, also to increase appetite. Side effects may include: changes in appetite, thirst or weight, diarrhea and high blood sugar. As to easing the side effects, this site is not medical professionals, so cannot possibly suggest anything. There are many products available, by prescription and over the counter that can help, but your medical condition as well as any other medications you are on have to be taken under consideration. The side effects should lessen as your body adjusts to the medication, but if they are troublesome, then you should speak to your doctor. Have you talked to them about it, yet?

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Is megestrol used to control hot flashes in men who have had prostate cancer radiation and harmone therapy? ## I did come across a study done on "Megestrol acetate for the prevention of hot flashes"; which you can view by following the link below: ncbi.nlm.nih.gov/pubmed/8028614 It seems as though it would be pretty effective, as the study mentioned that hot flashes were reduced by 85% after four weeks on megestrol. The degree of efficacy was also noted to be similar in men and women. On a side note: Megestrol is a man-made version of the human hormone progesterone, and is commonly used by cancer patients, so I do believe that it is an option for those who have had prostate cancer radiation and hormone therapy. I hope this information helps to answer your question!

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Megestrolac Liquid is used for creating appetite. Should this drug be taken by someone who has had both breasts removed due to cancer & is it a hormone? ## hola.ha todos ,bueno quero desirle que tengo un sangrado de ya ase mucho tempo , fui donde el doctor .y me hiso los exsamenes.,y me hiso unas preguntas que me dejaron con muchas dudads.bueno me reseto megestrol ac 40mg tab ## helo I have uno bleeding for long time, is for 1 year. my doctor me check all . ok my answer I teke megestrol ac 40mg tab. for what I drink this medicine ,this is for my bleeding, or for my anemia , I don't understand what is this? thanks, ## To answer, yes it is a hormone and virtually no synthetic ones are safe for someone that has had breast cancer. Learn more Megestrol AC details here. This is a synt...

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My father has kidney and bone cancer and has not been eating very much. His doctor just have him Megestrol AC 20mg tab stating that is has synthetic thc in it that should help his appetite. He has no problem taking that. However nowhere have I seen thc mentioned anywhere. So my question is. Is that at all true? Is there synthetic thc in this medication? Thank you for your help. ## No, there is no THC in this, synthetic or otherwise. Megestrol Acetate is actually a form of the hormone progesterone and it is used to increase appetite. You may find yourself more familiar with it if you think of woman taking hormone replacement therapy or contraceptives and the fact that it usually causes them to gain some weight, because it increases appetite. Learn more Megestrol Acetate details here. But...

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what drugs dose Megestrol contain ## Hello, Marie! How are you? That is the active ingredient. The FDA lists Megestrol as being most commonly used to treat the symptoms of advance breast or uterine cancer. Its typical side effects may possibly include diarrhea, nausea, insomnia, headache, increased appetite and weight gain. Is there anything else I can help with?

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My mother had congested heart failure and kidney failure 2 mo ago her kidneys are fine but she has a weak heart and lost all her appetite I need to show her Dr what are the ingredients of Megestrol AC to see if she can take this.He need to make sure it does not have steroids. Can you help me ? ## Megestrol Acetate is a steroidal progestin and progesterone derivative and, due to some of the side effects it can cause, it is probably not safe for her to use, because of the congestive heart failure. One of its side effects can be fluid retention, which is what actually caused CHF. Learn more Megestrol AC details here. Has he tried anything else to stimulate her appetite?

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side effects of megestrol ac ## Megestrol is used to treat advanced carcinoma of the breast and endometrium, in some cases, also to increase appetite. Side effects may include: changes in appetite, thirst or weight, diarrhea and high blood sugar. You can view more information in the link below... Please post back if you have any other questions or concerns.

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My doctor started me on 400mg of megestrol to gain weight. Because of how quickly I gained, it was reduced to 80mg two months later. Could that change in dosage be the cause of clitoral atrophy? ## Hello Jessa, According to the National Institute of Health and their warnings associated with megestrol acetate I don't any warnings or adverse reaction listings that states this medicine causes clitoral atrophy, however, it does list decreased libido as a common side effect. My understanding is that clitoral atrophy is the decreased size and feeling of the clitoris which could be the result of hormonal imbalance and or restricted blood flow. Due to the fact that the megestrol is a synthetic hormone based drug it is possible that despite not being listed as a common side effect it could p...

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Is Megestrol usually used for someone who can not gain weight? My husband has very little appetite and is very thin so he was prescribed Megestrol AC 40 mg. He does not have cancer or aids or anything like that. Thank you! ## Megestrol is a progesterone derivative and, when given in high doses, it can substantially increase appetite. Learn more: Are there any other questions or comments? ## Yes. My doc prescribed it to me because I told her I hardly ever had an appetite. I am 5' 11" and weighed 127. I was tired of being skinny and it being apart of others conversations. Just as your husband, I dont have cancer, AIDS, or any other sickness. Just a poor appetite. It works though. I gained 15 lbs in a little over a month. ## Mother had no appetite and was loosing weight; broke hip ...

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Will I still get my menstral cycle while taking 80 mg of megestrol acetate? I'm getting cramps and backache like I do before my period normally starts. ## Hi Vanessa, The only side effect of Megestrol that I found relating to the menstrual cycle is, "bleeding between menstrual periods". This is listed on a drug monograph from The US National Library of Medicine at: ncbi.nlm.nih.gov/pubmedhealth/PMHT0011066/?report=details#side_effects I don't know when you might expect to start your cycle again, but to my understanding, anything that alters your hormone levels (such as drugs like Megestrol) could inevitably result in changes to the timing of your cycle as well, since hormones are directly related. How long have you been taking it for?

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I was diagnosed with endometrial hyperplasia stage 3 - stage 4 is cancer. I had a D&C around november by gynecologist and was referred to robotic oncologist who prescribed the Megestrol. Since I am morbid obese, I did not know about the weight gain with the megestrol and have gained about 20 lbs in two months to my surprise; so when requesting a refill, i was told by pharmacist these tablets were for people who have trouble eating (not for cancer treatment as I was told by robotic oncologist). The oncologist is planning a hysterectomy around June 2015 because he wants me to loose as much weight as possible from a proposed bariatric surgery because the OR table has to be slanted in a certain position which makes my weight press on my chest making breathing hard for me. I do not know ...

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I'm elderly and have been taking megestrol, but would like to come off most of my meds... Is there an adjustment period or can you come off of megestrol fast? ## Hi Jerry, May I ask how long you've been taking Megestrol for? Often times, if someone has taken a medication long enough, there can be physical or psychological adjustment periods simply because the body is being cut off a chemical that it was used to having, even when the substance is benign in nature or non-habit-forming. However, if it's been a short while (say a few months or so), then in my opinion I don't see any reason why someone wouldn't be able to stop taking this medication cold turkey. On the other hand, because everyone reacts/responds differently (due to various underlying factors), the only w...

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I was given Megestrol Acetate for endometrial hyperplasia. The doctor said it would thin the uterine lining, but I haven't started a period since being on it. How does it thin the lining if i don't bleed? Or should I be bleeding? ## I was wondering the same thing. They told me that I shouldn't have a period and I haven't I spotted a little that's all. But I rarely had periods before I started megestrol. I have thicken endometium was 2.5cm after a month of taking the meds I'm at 3.5 so back to the doc I go. Wondering if anyone has had megestrol not work ? ## Megestrol contains a synthetic form of the hormone Progesterone, which is vital to a woman's healthy menstrual cycle. Each month, a woman will typically experience a large bolus of progesterone being relea...

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Hey my name is Michelle. I am 50 years old.the doctor did biospy for uterus my lining is 5.8. and my periods have been so heavy...He started me on megestrol to hopefully stop my period.will this work???I am premenopausal he said ..Thank you ..Please I need advice ## It could help, so you should take it as directed by your doctor. The FDA lists the typical side effects as possibly including nausea, dizziness, headache, irritability, and PMS-like symptoms. Have you started taking it, yet? Has there been any change? ## Hey...I'm starting it tomorrow...So I'm hoping it helps me.. ## I have been taking it for about 3 years. I am 43 and had heavier periods with severe pain, which we found out was from my uterus pushing on the arthritis in my lower back. My period has been gone all thi...

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Has anyone experienced urinary incontinence and/or swollen appendages as a side effect of taking Megestrol Acetate? ## Megestrol is a Progesterone derivative. These are not normal side effects to this medication, at all. Have you contacted your doctor about this, yet?

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I am post menopausal. 58 years old Vaginal ultrasound shows endometrial long at 11mm small fibroid and polyp. Endometrial Biopsy results were benign. Gyno put me on 40mg megestrol for 2 months. Took it for 1 week and my stomach bloated so much I looked 8 months pregnant. Cramps, headaches, the worst PMS I have ever had. No bleeding but running to bathroom thinking I was. I'd rather have a D&C to thin the lining and to be absolutely sure the fibroid and polyp are benign. I refuse to take megestrol - these make me crazy crampy severe PMS weight gaining pills and it's cruel to prescribe and expect a 58 year old postmenopausal woman to go thru this bodily hell. Menopause was bad enough. Not for me! Asking for D&C. ## I am very sorry about the issues you've experienced, t...

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I have been suffering from endometrial cancer grade1 stage 1A . After diagnosis my doctor has given me megestrol acetate 160 mg in the morning & 160 mg at night. I started taking it since 1-6-2016. After six months December, 16 another biopsy is done. It shows that the thickness of endometrum has reduced from 25 mm to 4.4 mm but cancer is still there. I am continuing my drug. How long can I continue or what should I do? I am 35 and I have no child. I had two miscarriages in 2014. Make me grateful by answering me please. ## Hello, I also take 320mg per day but take 2 tablets every 6 hours for a steady amount to remain in my system. I also eat a plan based diet - no packaged or junk food - and walk for an hour every day. You can continue the drug for 9 months BEFORE finding out if it ...

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I am petrified to take this pill. I am already significantly overweight with large abdominal hernias. Makes it difficult to walk. I am almost 60 and a heavy smoker. Is my doctor trying to kill me? My god... he said if I didn't take it I would probably develop uterine cancer as my lining is thick and I have heavy bleeding every month or so lasint 15 days or more. Anyone know of other options? I CANNOT GAIN MORE WEIGHT.... ## Hello, Smudge! How are you? Yes, there is a procedure they can do, basically a type of D&C that would effectively achieve the same thing, it removes the built up lining. However, if have heavy bleeding every month, it's odd that your lining would be that thick, that usually happens, when women don't bleed or have extremely light periods. You're al...

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Megestrol

Megestrol (INN, BAN) is a progestin of the 17α-hydroxyprogesterone group which was never marketed and is not currently used clinically.[1][2] Its acylated derivative megestrol acetate is also a progestogen, which, in contrast to megestrol itself, has been extensively used as a pharmaceutical drug.[1][2] Synthesis Megestrol synthesis:[3] U.S. Patent 2,891,079 See also Megestrol acetate Medroxyprogestero...