Enbrel

Etanercept

Etanercept, sold under the brand name Enbrel among others, is a biologic medical product that is used to treat autoimmune diseases by interfering with tumor necrosis factor (TNF), a soluble inflammatory cytokine, by acting as a TNF inhibitor. It has U.S. Food and Drug Administration (FDA) approval to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. Tumor necrosis factor alpha (TNFα) is the "master regulator" o...

just wondering did anyone have a bad reaction to enbrel? I had to stop after 7 weeks. ## Hello, Molly! How are you? Yes, it has happened to others, so it's not just you. It just seems to be one of those medications that either works well for someone, or it doesn't, no middle ground. What else have you tried?

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Have any of you Enbrel users experienced persistant muscle pain involving the entire leg? This pain is of the level that interrupts sleep. ## does not sound like side effect but sounds like you should see a nurologist I had nerve problems along with RA and what a diffrence to find that out always thought it was the RA but I had two things wrong then I was put on diffrent meds. feel like a new women. feel free to email me! ## Thanks for your input Donna - It took several specialists, and more than a few tests to determine that I too had a problem other than the arthritis! I did eventually end up witha Neurologist - and the problem was pin-pointed. Seems we have similar stories as I too feel like a new person - so glad it wasn't more Arthritis to deal with and especially glad in was i...

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Been on Enbrel about 3 months I have an over active immune system which causes multiple issues like psoriatic arthritis and all that goes with that along with deformed joints, psoriatic skin eruptions, IBS etc. As my immune system was lowered much of the pain and stiffness, skin eruptions and IBS slowly disappeared. I was getting excited about feeling better when out of the blue I started feeling a tingling and itching in my back, then the pain came as I realized I was having a shingles attack! I immediately went to my PC and he put me on an antiviral drug. I’m about three weeks into my shingles attack now. The antiviral drug seems to have stopped the progression of the shingles and so far it has not erupted in to open sores. The pain and itching remains but I’m thankful tha...

I have been on enbrel now for weeks with dreadful side effects this week. I feel so ill. I slept for three days, have painful legs and a sore throat..... ## I have been taking Enbrel for three weeks and although my RA has reduced significantly the side effects are rough. I a, sick to my stomach, I'm crying at the drop of a hat and I have no energy, just to name a few. ## I'm sorry that you've both been having such problems. Are either of you feeling better, yet? These are listed among the possible side effects provided by the FDA. You may also experience bladder pain, blurred vision, diarrhea and abdominal pain. Can anyone else that's been on this chime in with their experiences? ## Dr. decided to give Enbel another try. I'm still having difficulties with site inject...

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Since starting Enbrel 2 years ago for PA I have lost 24 pounds. The doc claims he has never had a patient react that way. It has helped my neck and psoriasis somewhat. I've had other tests done for the weight loss... thyroid, blood, colonoscopy. ..nothing shows. Weight loss is great if you know why, but I don't. Not happy. ## Weight loss is listed by the FDA as a possible side effect of Enbrel. You may also experience nausea, headache, hair loss and stomach pain. They list it as being incidence unknown, which means that it has been proven to be caused in some people by this medication, but exact statistics on how often it happens are not available. Are you on any other medications? ## Sometimes you just lose weight because you feel better so you’re moving more

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Was wondering if anyone is paying out of pocket for their Enbrel? ## Enbrel has a page on their website to help people find financial assistance, if needed. The FDA lists the typical side effects of Enbrel as possibly including administration site reactions, nausea, headache, cough, and weakness. Ref: Enbrel Information Is there anything else I can help with?

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Hi, 8 years ago I started taking Enbrel. I had a bad knee injury in HS and years later developed arthritis in my right knee. I do not have arthritis in any other joints. Nothing worked to take the swelling out of my knee and it was very difficult to walk. My RA doctor prescribed Enbrel and it has been amazing for me. No side effects and my knee inflammation disappeared. Overtime however my knee was deteriorating. I asked my RA doctor if a knee replacement would get me off the Enbrel. He said no. I would still need to take the shots and that my arthritis is an auto immune issue. 6 months later I went to see my RA doctor again but he was not in. The RA doctor in his place that day told me that yes, if I don't have arthritis in any other joints, a knee replacement will get rid of my ar...

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I've been on Enbrel for a number of months now and have found it useful but my joint pain is getting worse and returning to levels of pain I had before using it. I am on 50ml autoinjection 1x weekly and was wondering if others have had the same problem and if they increased their injections to 2x weekly or not? ## Hello Cas, It could possibly be that your condition is worsening or that you are simply forming a tolerance to the medication. This sort of thing is hard enough for medical professionals to properly diagnose and far harder for those of us on the internet who wish to help you, I suggest that you schedule a visit with your primary care doctor and discuss this matter with them as they will be best equipped to help you manage the situation properly. Best of luck. ## Thank you ...

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I was diagnosed with RA 2003. Started out with methotrexate until my liver showed signs. Then went on Enbrel for 10 yrs. Other than inj. site issues it was great! No flares. You'd never know I had RA. Istarted having RA symtoms (you never forget them). My next dr appointment I was met bya dr I didn't know and she said my Enbrel was no longer working for me and swtched me to Humira. I did my first IV n the drs office w/o a problem. Second (2 wks) the first site puffed up. This was odd. No other problem so the 3rd inj. I rotated leg/stomach/leg. I have yet to feel more than a 4 day relief after 3 months. I watch my diet for inflammatory foods, stopped alot of food supplements and still not any better. Is Enbrel a stronger med than Humira? Can't seem to get much help from my RA...

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Has anyone tried fasting on the day before taking Enbrel? I heard it works for Methotrexate but I was wondering if it worked to lessen the nausea after injecting Enbrel? ## Hello Mary, I've looked all over but I can't seem to find anywhere that supports this idea, not even from forums dedicated to discussing Enbrel. I was able to find a forum on the "livingwithpsoriaticarthritis" organization website that discusses the matter of nausea but most users state that this only happens for the first few shots and subsides within a few hours. In regards to your specific question of fasting before the injection I would advise you discuss this matter with your doctor first to ensure that it is safe and will have no negative effects on you. If your doctor gives you the go ahead I s...

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Enbrel induced- Optic Neuritis-Hi everyone, I am 29 years old and took Enbrel for 2 1/2 year (from 2010-2013). I had to discontinue use because I developed optic neuritis. IN the past 15 months my vision has worsened. My latest eye scan showed that I have lost 25% vision in my right eye and 10% vision in my left, IN 1 YEAR, due to the Enbrel induced ON. Please get your eyes checked if you are taking a biologic!!! Most biologics are associated with ON. Symptoms start as dull to sharp eye pain, vision changes, and head aches. Very important!!! The vision loss I have experienced in permanent but if you catch it early on it can be reversible. -------Much Love-----Elisabeth ## Hi, I am 52 years old,have had Juvenile Rheumatoid Arthritis since I was 12 yrs old. Been on multiple medications ov...

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I was taking pre-filled injections of Enbrel for 4 weeks and didn’t really see much difference until I switched to the click-pen on Wednesday, which, since then I have had scabs all over my face and an itching sensation like crazy. It looks horrible, like a bad case of acne and blisters and scabs. ## Those can be normal side effects of Enbrel, and it does usually take several weeks for the side effects to fully manifest. You may also experience nausea, weakness, sore throat, mood changes, and chills. How are you doing now? Has there been any change? Are you on any other medications? ## How is it going now? Is it alright now? I am also planning some Enbrel inj's., and I want to ensure they will not mess with the other medications I take. I know I have to consult a medical speci...

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I have taken Enbrel for Psoriasis for the last 4 years. The side effect I had was allergic. I stopped taking it for one month and my Psoriasis became worse. Back and leg pain started and they were unbearable. I have to be on medication and am addicted to the drug. Is this normal? ## It is very common to experience withdrawal symptoms and rebound conditions when you abruptly stop taking any medication. If anyone has any experience with this, please post!

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I was wondering if anyone on Enbrel has taken covid-19 shot, and had an allergic reaction? ## You can read here about which medications should be paused, when getting your COVID vaccine, and possible issues that may arise. Enbrel is listed as one that it is not necessary to stop, so it seems there haven't been any issues reported. The first COVID shot doesn't usually cause many side effects, other than a sore arm, with some possible bruising, at the administration site, but the second dose my cause nausea, headache, fever, chills, and joint/muscle aches. I received my second dose of the Moderna one, today, and so far, I've been feeling a little off, and have a headache setting in. Can anyone that's on Enbrel and received the vaccine post with their experience?

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Hello I am from India. My wife (52 years old) is suffering from Rheumatoid Arthritis from last 12 years. Recently we consulted with doc. he told us about Enbrel (Etacept 25mg inj.) and suggested to take Etacept 25mg twice a week for 3 month. My main concern is it is very very expensive in India even though I can afford 24 doses (for 3 months). Doctor told us after 3 month you don't need these treatment. I want to know its really true?? The result of Etacept 25mg will life long?? Or it used just to make temporary relief?? After reading above discussion I come to know peoples are using this for year n year. Which is economically not possible in my case. Please help me to decide whether to start this treatment or not. ## So I understood you have to take Enbrel for a long time, when not...

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I have been on Enbrel for several years and wanted to know if anyone in this group has taken the new shingles vaccine Shingrix? If so what was your response? A nurse at Amgen, the maker of Enbrel said she couldn't advise about taking Shingrix while on Enbrel. The Shingrix literature says those on Immune suppressors would get a lesser shingles protective response. Shingrix is not a live vaccine and I think that is the only thing prohibited while on Enbrel. Thanks for your help. ## Hello Mark, I took a look at the manufacturers page and like you previously stated it says that you should not take any live vaccines while on the medication, however, right above that line it states that you should take all vaccines prior to starting this medication. I believe that because they went out of...

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I have been on Enbrel now for a couple of years. Will I experience withdrawal if I go off the drug? Do I have to do it gradually? ## Hello, Erena! How are you? Yes, after taking it for years, it is probably best to do a slow taper. It's not a narcotic, so it's not likely to cause severe withdrawal symptoms, but some of them can still be quite annoying. Learn more Enbrel details here. Have you discussed it with your doctor? ## I have tajen embrel for a year and my ins changed but i seem to be having withdrawal symtoms like rashes. Loose bowls and bone aches is rhis possible ## What are the withdrawal symptoms?

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Long read, need help! 59 year of male diagnosed with Psoriatic Arthritis 2 1/2 years ago. Tried going Vegan and took the insurance-required Methotrexate for 3 months with no relief whatsoever. On the advice of my RA I started the 50mg injections of Enbrel. Within 2 days I noticed a big difference and was pain free within a month. Fast forward to a month ago. Started getting a fever to which I've seen as high as 103.3°. Oddly enough, the Enbrel stopped working at the same and went back to severe pain and stiffness within 2 weeks. Went and had all kinds of blood work with no infection found. All Covid & Flu tests were negative. So I went the emergency room 3 days ago and have cat scans, ultrasounds, MRI's and they cannot find source of the fever. Last injection was 10 day...

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When considering Enbrel as a medicine for Psoraisis in a More than 50% case on the body, Does Fenethylline (Captagon) pills have any Undesired or Bad Effects on the medication incase it's taken when needed, ## Enbrel contains the active ingredient Entanercept and is used to treat auto-immune conditions. Fenethylline/Captagon is a stimulant. I do not see anything listed that contraindicates using them together, however, this site is not medical professionals, so you should consult your doctor or pharmacist to be certain. Is your doctor aware that you are taking both? ## very importent topic nowadays

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