Xpovio

Active Ingredient(s): Selinexor
FDA Approved: * July 3, 2019
Pharm Company: * KARYOPHARM THERAPEUTICS INC
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Xpovio Overview

Selinexor (INN, trade name Xpovio; codenamed KPT-330) is a selective inhibitor of nuclear export used as an anti-cancer drug. It works by quasi-irreversibly binding to exportin 1 and thus blocking the transport of several proteins involved in cancer-cell growth from the cell nucleus to the cytoplasm, which ultimately arrests the cell cycle and leads to apoptosis.[1] It is the first drug with this mechanism of action.[2][3] Selinexor was granted ...

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Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Selinexor

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Possible Dosages for this and Related Drugs:

NDC Database Records for Xpovio: (1 result)

Sorted by National Drug Code

• 72237-101 Xpovio 20 mg Oral Tablet, Film Coated by Karyopharm Therapeutics Inc.

Other drugs which contain Selinexor or a similar ingredient: (1 result)

• SELINEXOR