Active Ingredient(s):Selinexor FDA Approved: * July 3, 2019 Pharm Company: *KARYOPHARM THERAPEUTICS INC Category:Cancer
Selinexor sold under the brand name Xpovio among others, is a selective inhibitor of nuclear export used as an anti-cancer medication. It works by blocking the action of exportin 1 and thus blocking the transport of several proteins involved in cancer-cell growth from the cell nucleus to the cytoplasm, which ultimately arrests the cell cycle and leads to apoptosis. It is the first drug with this mechanism of action.
* May have multiple approval dates, manufacturers, or labelers.