XiaflexActive Ingredient(s): Collagenase Clostridium Histolyticum
FDA Approved: * February 2, 2010
Pharm Company: * AUXILIUM PHARMS
Category: Skin Care
Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a virulence factor, facilitating the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs. Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secret... [wikipedia]* May have multiple approval dates, manufacturers, or labelers.