Xeljanz

Active Ingredient(s): Tofacitinib Citrate
FDA Approved: * November 6, 2012
Pharm Company: * PFIZER
Category: Immunosuppressive

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Xeljanz Overview

Tofacitinib, sold under the brand Xeljanz among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.[1][2] Common side effects include diarrhea, headache, and high blood pressure.[1] Serious side effects may include infections and the development of cancer.[1] It is in the janus kinase (JAK) inhibitor class, discovered and developed by the National Institutes of Health and Pfize...

Read more Xeljanz Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Tofacitinib

Recent Xeljanz Forums: RSS Feed

Xeljanz: Joint pain, insomnia and chills

I've bern on xeljanz for 3 months for RA. It worked great at first but the last month I've had joint pain and the stiffness return along with constant chills and insomnia since commencing this drug. Has anyone else experienced these symptoms? ## Hello Sandra, I did some research and I sourced the list of adverse reactions that the manufacturer claims that are associated with Xeljanz. upper respiratory tract infections, headache, diarrhea, and. cold symptoms such as sore throat, runny or stuffy nose. The chills that you are describing as feeling could be part of the cold symptoms that they claim some of their users are experiencing. As for the joint pain and stiffness there could be a number of reasons that the medicine stop working. One of them is that your body has started to d...

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xeljanz 11 mg and oxycodone/apap 5-325 together

Can these two medications be used together (xeljanz 11mg and oxycodone/apap 5-325 mg)? I have RA but just started xeljanz and am still healing from surgery in pain. ## Yes you can take these medications together. There are no drug interactions with the two drugs

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Accidental double dose of Xeljanz

Can I cause harm to my body if I accidentally took two extended-release Xeljanz 11 mg tablets? ## From what I could gather, Xeljanz (Tofacitinib Citrate) is immunosuppressive, which means that your immune system could potentially be compromised more easily with an increased dosage. However, if you are in otherwise good health, then I'm of the opinion that you should be fine after that second tablet wears off... Nevertheless, I would still encourage you to let your prescribing doctor and/or pharmacist know just to be on the safe side, since this would ultimately mean that you'd have 1 less tablet to take prior to getting a refill -and whether or not this is something you'd have to be concerned about as well? I hope this helps and wish you good health!

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stopping xeljanz

I was on xeljanz for 4 months, unfortunately had to stop last week due to decreased platette count. Since then I became very depressed and increased anger, I could even say I have rage, which is very unlike me. Has anyone experienced this by stopping this drug? Please respond. I'm very concerned over this behavior. ## Hi Susan, Sorry to hear about your experience coming off of Xeljanz. It sounds like your best bet would probably be to sit down and talk with your doctor about ways to provide more relief from your symptoms; at least until they start to subside. When it comes to symptoms of anger, depression, and irritability, I believe those are really just chemical imbalances trying to sort themselves out as your body continues to adjust to not having the medication. Knowing that, ho...

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Xeljanz and Irritable mood

My sister started xeljanz for r.a. about one month ago. I have noticed irritability...something she rarely ever exhibits. Just wondering if that is a common or uncommon side effect of xeljanz.....and could xeljanz increase blood pressure? ## That can be a normal side effect of most medications, according to the FDA, as well as the blood pressure elevations. Is this the only medication she is taking? Is she displaying any other symptoms?

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Stopped Xeljanz

I started on Xeljanz Feb 5; 5 mg twice a day. Within a week I experienced a very raw, sore tongue, mouth, loud ringing in my ears, blurred vision and dizziness. Anyone else experienced any of these? ## Wow! I'm sorry about the experience you had. Are you feeling better, now? Has anyone else experienced this? Blurred vision and dizziness are listed as typical side effects of this medication, by the FDA. They also list ear congestion as being possible, so that may be why you experienced the ringing. It can also cause a sort throat, but I didn't see anything about the rawness.

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xeljanz and colitis

I have colitis and one of the size effect xeljanz is diarrhea. Has anyone had any experience with that. I'm was on Humira but the Dr wants me to switch to xeljanz. Thank you ## Hi Barb, Sorry to hear about your condition. I see what you're saying though about having colitis along with the possibility of Xeljanz (tofacitinib) causing diarrhea as well. However the thing about these medications is that there's really no way to tell ahead of time how you might end up reacting to it until you "take it for a test drive" if you will. A lot of these side effects only occur in a smaller percentage of patients, but the risk factor is always going to be there while you're taking the medication. In such cases, my opinion would be to weigh out the benefits vs risks and see if...

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Pain level

I just started xeljanz 6 days ago 10mg yesterday felt only slight pain so I went to gym, swimming, and was more active. Today the pain came back. Just wondering if I over did it or normal. How long did it take before you noticed any improvement? ## Hi, Susan! Sorry that you're in pain. Are you feeling any better? You may have overdone it getting that active that soon. I know we always want to do that, just rush out and do everything we've been unable to do for awhile, but sometimes you just can't let yourself, because your body requires more time. Learn more Xeljanz details here.

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Possible Dosages for this and Related Drugs:

Tofacitinib Citrate
  • Tablet: 10mg, 5mg
  • Tablet, Extended Release: 11mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Xeljanz: (4 results)

Sorted by National Drug Code
  • 0069-1001 Xeljanz 5 mg Oral Tablet by Pfizer Laboratories Div Pfizer Inc
  • 0069-1002 Xeljanz 10 mg Oral Tablet, Film Coated by Pfizer Laboratories Div Pfizer Inc
  • 63539-012 Xeljanz 5 mg Oral Tablet by U.S. Pharmaceuticals
  • 63539-016 Xeljanz 10 mg Oral Tablet, Film Coated by U.S. Pharmaceuticals

Other drugs which contain Tofacitinib Citrate or a similar ingredient: (2 results)

Related Xeljanz Topics:

xeljanz and colitis
I have colitis and one of the size effect xeljanz is diarrhea. Has anyone had any experience with that. I'm was on H... 3 replies
Xeljanz: Joint pain, insomnia and chills
I've bern on xeljanz for 3 months for RA. It worked great at first but the last month I've had joint pain and th... 1 reply
xeljanz 11 mg and oxycodone/apap 5-325 together
Can these two medications be used together (xeljanz 11mg and oxycodone/apap 5-325 mg)? I have RA but just started xeljan... 1 reply
Xeljanz and Irritable mood
My sister started xeljanz for r.a. about one month ago. I have noticed irritability...something she rarely ever exhibits... 1 reply
Stopped Xeljanz
I started on Xeljanz Feb 5; 5 mg twice a day. Within a week I experienced a very raw, sore tongue, mouth, loud ringing i... 1 reply
stopping xeljanz
I was on xeljanz for 4 months, unfortunately had to stop last week due to decreased platette count. Since then I became ... 5 replies
Accidental double dose of Xeljanz
Can I cause harm to my body if I accidentally took two extended-release Xeljanz 11 mg tablets? ## From what I could gath... 1 reply






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