Xalkori

Active Ingredient(s): Crizotinib
FDA Approved: * August 26, 2011
Pharm Company: * PFIZER
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Xalkori Overview

Crizotinib (trade name Xalkori,[1] Pfizer) is an anti-cancer drug acting as an ALK (anaplastic lymphoma kinase) and ROS1 (c-ros oncogene 1) inhibitor,[2][3][4] approved for treatment of some non-small cell lung carcinoma (NSCLC) in the US and some other countries, and undergoing clinical trials testing its safety and efficacy in anaplastic large cell lymphoma, neuroblastoma, and other advanced solid tumors in both adults and chil...

Read more Xalkori Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Crizotinib

Recent Xalkori Forums: RSS Feed

xalkori and acid reflux/gerd

I have been on xalkori for about a year now; diagnosed with stage IV lung cancer that mets to the pancreas. Lately, I have been waking up in the middle of the night with really bad acid reflux... wondering if anyone else taking Xalkori has experienced this. ## I have been on Xalkori for 8 months and i have sometimes experienced acid reflux as well, my doctor said he wasn't sure Xalkori could be blamed for that. I have noticed that the reflux mainly happens when I have a heavy meal for dinner. So what i do now is that i drink a glass of water with a little baking soda before going to bed and it seems to work well against the acidity in the stomach. Moreover, I put an extra pillow under my head and it's much better like this. I think that a light dinner can partly solve the proble...

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Xalkori results

My husband has metastatic lung cancer and has been on Xalkori. The drug appears to be working (the cancer has not spread anymore). I am looking to hear stories about other people's experience using the drug. ## Very glad to read that it's working for him. However, it seems you're the first person that's posted on our site about this medication. We do have a monograph page for it here: Is he experiencing any side effects? ## I started on Xalkori last fall. I am feeling better than I have in 3-1/2 years. My shortness of breath has been almost entirely eliminated. I feel my energy and motivation coming back. ## My mother started Zalkori 6 days ago. It has really knocked her down quite a bit. Lots of stomach upset and she is very week. Just hoping that she can adjust to the ...

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xalkori after effects

I have been taking this drug for 5 weeks and am having almost no side effects except odema--swelling of the legs and hands-anyone else have this--bowels appetite all good and sleeping well Thanks Roger ## Hi Roger I've been taking Xalkori for 11 months and the last seven or eight months have seen an huge increase in oedema of hands / arms and ankles / feet. We're trying various options, decreasing the dose, taking diuretics which has some effect but not if you're hot / flying / walking a lot. I'm guessing we're stuck with it - goodbye to posh shoes and gloves... I've found side effects to come and go. Nausea and bowel issues are my constants although I'm used to it now, and stripy vision at night. But the oedema is by far the most debilitating. ## Hello again...

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Food aversions

My mom has only been on Xalkori for a few weeks and since switching to it everything she eats has a sweet flavor and turns to a disgusting oily crisco mush. She's struggling to eat or keep anything down. Has anyone else had this experience? What are you eating that is working for you? ## Hello, Rebecca! How is your mom doing? Has there been any change? According to the FDA, it can cause a change in taste as a side effect, along with nausea, dizziness, headache, and decreased appetite. However, if it is affecting her so severely that she can barely eat, she should consult her doctor. It is also very important that she take in proper nutrition.

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Xalkori edema and lower intestinal tract

I started taking Xalkori about 9 weeks ago for stage IV ROS1 lung caner. My cough disappeared after the first pill so I feel very fortunate that I'm responding so well to it. I'm slowly getting back my energy and am able to breath easily now. However, I have edema in my ankles and feet and my digestive tract has been hard to regulate. I want to stay active but my feet and ankles swell so much I can't be on them all day. Has anyone found a holistic or natural approach to these side effects that works and is safe to take with the pills? ## There's no way to know what natural remedies may be safe to take given your medical condition and the medication you're taking. Thus, it would really be best to consult your doctor to see what may help with the edema. It is a common ...

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Xalcori drug life span

What's the longest people have lived for on Xalcori? I have a small lung cancer that spread to my spine. ## Hi I've been on the drug 5 months my recent scans showed it is working hopefully for many years please God best of luck for the future. ## A friend has been on the drug for a year and it is working very well for him, thank God. I believe it will work very well for you too!!

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Xalkori cost on Medicare--Mexico, Cananda, anything???

My mom was diagnosed with stage IV NSCLC with only BM two weeks ago. The day before she was to get her port for Carbo/Taxol (which Medicare had pre-approved), the called and said her ALK came back positive so new plan is Xalkori. She went to get the med and the price is astronomical. She is on Medicare and there is absolutely no way that she can afford the drug, and no way even spread between the three kids we can make it work. Has anyone obtained the drug in Canada or Mexico? We're willing to do anything legal to get this for her. She got a grant that will cover two month of it, but after that we just don't know what to do. ## Is your mom low income? If she is, she might qualify for help paying her Medicare co/pay and other Medicare expenses. I have put a link below. She can al...

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Xalkori femme de 28 ans

Bonjour à tous je suis une jeune réunionnaise de 28 ans (i'm a woman aged 28 leav in Reunion Island)et je suis atteinte de cancer aux poumons depuis 3 ans. Je prends XALKORI depuis août 2013, (i take Xalkori since august 2013) jmon cancer a débuté peu après on accouchement (my son's birth) j'aimerai savoir quelle est l'efficacité en terme de temps de ce traitement, puis-je encore espérer le prendre longtemps? (How long do you take it, for how years is it works?) j'aimerai avoir des gens à qui parler car ceux qui sont autour de moi me soutiennent mais c'est réconfortant de parler aux gens de la même situation (i would talk about this with people who have this cancer and difficulties) Thanks a lot for your answ...

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conceiving a baby while on Xalkori/Crizotinib

Hello, I am new to this forum and pleased to meet you all. My partner, a 27-year old man is being treated with Crizotinib since September 2012. He was diagnosed with Non-Hodgkin Anaplastic T cells Lymphoma ALK+. After chemo we decided to continue his treatment with Crizotinib (on a clinical trial) rather than following the standard path of autologous stem cell transplant. He has never suspended the treatment apart from short periods (10 days) when his blood work showed he needed to (low white cells). He has been on complete remission since (he actually had a negative CT scan also before starting but his PCR/NPM-ALK from peripheral blood was positive suggesting the illness was still present in the blood and a high chance of relapse). Being a fairly young couple we have been wondering abo...

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Xalkori for thyroid cancer metastasis in lungs?

Hello my name is Erica & I was diagnosed with papillary thyroid cancer in 2005 at the age of 15. At the time I was diagnosed it had already spread to my lungs. I've undergone several surgeries & have received SEVEN, yes 7 round of radioactive iodine. My type of cancer is supposed to be highly responsive to this type of treatment but after almost 8 years I still have the cancer. Lately I've been feeling weaker, I do take daily medication but haven't been insured or affort seeing my oncologist because my childrens cancer insurance expired when I turned 21. Im just trying to look for answers, and have something to present to a doctor whenI finally do see one again. ## You can learn more about it here: Otherwise, I'm afraid I can't help much, since I am not very ...

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Possible Dosages for this and Related Drugs:

Crizotinib
  • Capsule: 200mg, 250mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Xalkori: (2 results)

Sorted by National Drug Code
  • 0069-8140 Xalkori 250 mg Oral Capsule by Pfizer Laboratories Div Pfizer Inc
  • 0069-8141 Xalkori 200 mg Oral Capsule by Pfizer Laboratories Div Pfizer Inc

Other drugs which contain Crizotinib or a similar ingredient: (1 result)

Related Xalkori Topics:

Xalkori results
My husband has metastatic lung cancer and has been on Xalkori. The drug appears to be working (the cancer has not spread... 27 replies
Xalkori cost on Medicare--Mexico, Cananda, anything???
My mom was diagnosed with stage IV NSCLC with only BM two weeks ago. The day before she was to get her port for Carbo/Ta... 10 replies
xalkori and acid reflux/gerd
I have been on xalkori for about a year now; diagnosed with stage IV lung cancer that mets to the pancreas. Lately, I ha... 4 replies
xalkori after effects
I have been taking this drug for 5 weeks and am having almost no side effects except odema--swelling of the legs and han... 3 replies
Xalkori for thyroid cancer metastasis in lungs?
Hello my name is Erica & I was diagnosed with papillary thyroid cancer in 2005 at the age of 15. At the time I was d... 3 replies
Xalkori edema and lower intestinal tract
I started taking Xalkori about 9 weeks ago for stage IV ROS1 lung caner. My cough disappeared after the first pill so I ... 2 replies
xalkori side effects
My brother in law was just diagnosed with stage IV lung cancer. It has metastasized to his brain, liver, and bones. He s... 2 replies
Xalkori fatigue and weakness
I have been taking Xalkori since the end of May 2012. In the first 30 days, I had trouble keeping food down, lost 20 lbs... 2 replies
Xalkori
I have been taking Xalkori since the end of May 2012. In the first 30 days, I had trouble keeping food down, lost 20 lbs... 2 replies
Xalkori femme de 28 ans
Bonjour à tous je suis une jeune réunionnaise de 28 ans (i'm a woman aged 28 leav in Reunion Island)et je ... 1 reply






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