Active Ingredient(s): Mechlorethamine
FDA Approved: * August 23, 2013
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Valchlor Overview

Chlormethine (INN, BAN), also known as mechlorethamine (USAN, USP), mustine, HN2, and (in post-Soviet states) embikhin (), is a nitrogen mustard sold under the brand name Mustargen among others. It is the prototype of alkylating agents, a group of anticancer chemotherapeutic drugs. It works by binding to DNA, crosslinking two strands and preventing cell duplication. It binds to the N7 nitrogen on the DNA base guanine. As the chemical is a blister agent, its use is strongly restricted within t...

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Possible Dosages for this and Related Drugs:

  • Gel: 0.016%, 0.02%
  • Injection: 10mg, 10mg/vial
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Valchlor: (3 results)

Sorted by National Drug Code
  • 42427-002 Valchlor .012 g/60g Topical Gel by Ceptaris Therapeutics, Inc.
  • 66215-016 Valchlor .012 g/60g Topical Gel by Actelion Pharmaceuticals Us, Inc.
  • 69639-120 Valchlor .012 g/60g Topical Gel by Helsinn Therapeutics (U.s.), Inc.

Other drugs which contain Mechlorethamine or a similar ingredient: (2 results)