Active Ingredient(s):Dihydroergotamine Mesylate FDA Approved: * September 2, 2021 Pharm Company: *IMPEL NEUROPHARMA Category:Migraine / Tension Headache
Dihydroergotamine (DHE), sold under the brand names D.H.E. 45 and Migranal among others, is an ergot alkaloid used to treat migraines. It is a derivative of ergotamine. It is administered as a nasal spray or injection and has an efficacy similar to that of sumatriptan. Nausea is a common side effect.
It has similar actions to the triptans, acting as an agonist to the serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but a...
* May have multiple approval dates, manufacturers, or labelers.