Active Ingredient(s):Ibalizumab-uiyk FDA Approved: * March 6, 2018 Pharm Company: *TAIMED BIOLOGICS USA Category:HIV / AIDS
Ibalizumab (trade name Trogarzo) is a non-immunosuppressive humanised monoclonal antibody that binds CD4, the primary receptor for HIV, and inhibits HIV from entering cells. It is a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4 cell. Post-attachment inhibitors are a subclass of HIV drugs called entry inhibitors.
In a Phase III trial with 48 weeks of follo...
* May have multiple approval dates, manufacturers, or labelers.