FDA Approved: * March 26, 2015
Pharm Company: * PAR PHARM INC
Category: Parkinsons

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Tolcapone Overview

Tolcapone, sold under the brand name Tasmar, is a medication used to treat Parkinson's disease (PD). It is a selective, potent and reversible nitrocatechol-type inhibitor of the enzyme catechol-O-methyltransferase (COMT).[1] It has demonstrated significant liver toxicity, which has led to suspension of marketing authorisations in a number of countries. In comparison with entacapone, another nitrocatechol COMT inhibitor, tolcapone has a longer half life (2.9 hours vs. 0.8 hour...

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Possible Dosages for this and Related Drugs:

  • Tablet: 100mg, 200mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Tolcapone: (3 results)

Sorted by National Drug Code
  • 49884-254 Tolcapone 100 1/1 Oral Tablet, Coated by Par Pharmaceutical Companies, Inc.
  • 50742-193 Tolcapone 100 mg Oral Tablet by Ingenus Pharmaceuticals, LLC
  • 68682-938 Tolcapone 100 mg Oral Tablet, Film Coated by Oceanside Pharmaceuticals

Other drugs which contain Tolcapone or a similar ingredient: (1 result)