Simponi Aria

Active Ingredient(s): Golimumab
FDA Approved: * July 18, 2013
Pharm Company: * JANSSEN BIOTECH
Category: Arthritis

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Simponi Aria Overview

Golimumab (CNTO 148)[1] is a human monoclonal antibody which is used as an immunosuppressive drug and marketed under the brand name Simponi. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule[2] and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellaular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor (VEGF) demon...

Read more Simponi Aria Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Golimumab

Recent Simponi Aria Forums: RSS Feed

Intestinal bleeding from Simponi Aria

I just started simponi aria infusion 2 mos ago, Just got my second infusion, immediately the next day I started bleeding from rectum when going to bathroom. So is this bleeding from my recent radiation for prostrate cancer, the continuing prendison I am on or from the simponi aria itself. Can anyone that may be getting this treatment for RA get back to me. Thanks ## Hello, John! How are you doing? Please seek medical attention, that type of bleeding could be something dangerous that requires immediate treatment. Can you post back and update me on how you're doing? Are those the only medications that you're on? ## The bleeding is bright red, not a lot and stops for a couple of days and then starts again. Saw the radiation doc. Told me to take stool softener and use this supositor...

Updated
Heart pounding in my chest and head

Since getting my first Simponi Aria infusion 3 days ago, I have been well aware of my heart beating really hard in my chest, especially when I lay down to sleep at night. It's not beating fast or rapidly but just beating hard. I lay hear and count the beats while I try to go to sleep. I have also been feeling some tightness in my chest, kind of like my heart has pressure on it. I wouldn't be concerned about it except that I was recently diagnosed with a heart murmur and mild aortic stenosis. My dad passed away last year from a massive heart attack and he had severe aortic stenosis. He had aortic valve replacement which only lasted him 3 years before he died. My RA is pretty bad and I really want this drug Simponi Aria to work for me but this heart condition is really scaring me....

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Possible Dosages for this and Related Drugs:

Golimumab
  • Injection: 50mg, 50mg/4ml
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Simponi Aria: (1 result)

Sorted by National Drug Code
  • 57894-350 Simponi Aria 50 mg/4ml Intravenous Solution by Janssen Biotech, Inc.

Other drugs which contain Golimumab or a similar ingredient: (2 results)

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Intestinal bleeding from Simponi Aria
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