Simponi AriaActive Ingredient(s): Golimumab
FDA Approved: * July 18, 2013
Pharm Company: * JANSSEN BIOTECH
Golimumab is a human monoclonal antibody which is used as an immunosuppressive medication and sold under the brand name Simponi. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellaular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor (VEGF) demonstrates golimumab as an effe... [wikipedia]* May have multiple approval dates, manufacturers, or labelers.
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