Active Ingredient(s):Cisapride FDA Approved: * July 29, 1993 Pharm Company: *JANSSEN PHARMA Category:Heart Burn / Indigestion
Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. It has been sold under the trade names Prepulsid (Janssen-Ortho) and Propulsid (in the United States). It was discovered by Janssen Pharmaceuticals in 1980. In many countries, it has been eit...
* May have multiple approval dates, manufacturers, or labelers. 3 Discussions