Active Ingredient(s): Desvenlafaxine Succinate
FDA Approved: * February 29, 2008
Pharm Company: * WYETH PHARMS INC
Category: Antidepressant

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Pristiq Overview

Desvenlafaxine (brand name: Pristiq, Desfax, Ellefore), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.[1] Contents 1 Medical uses 2 Adverse effects 3 Ph...

Read more Pristiq Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Pristiq Forums: RSS Feed

Switching from pristiq to generic pristiq
124 Replies RSS Share
I was switched from Pristiq to generic Pristiq which if I understand right, is really Effexor. Is there a possibility this could be causing my severe fatigue? Has this happened to anyone else out there? ## My Insurance switched me to the generic (not my choice) about 3-4 weeks ago. Depression has been creeping in and I'm pretty concerned. Yesterday/last night was bad. Today was OK but my energy is not what it should be and my thinking/mood is not where it should be. Hoping to switch back but I don't know what is happening with the insurance...there is a $1000 penalty to go back to name brand!! ## Insurance is disgusting!! I actually feel ok depression wise and the fatigue turned out to be something else. I hope you stay stable ## Thanks. I'm glad your medication isn't th...
Updated 6 hours ago.
3 Replies RSS Share
WAS ON PRISTIQ FOR 3 MONTHS AND WENT OFF BECAUSE INS, WON'T PAY. WHAT ARE THE SYMPTONS GOING OFF THE MEDICINE. ## Nausea and vomiting ## i just posted in another forum, but i have now done 2 weeks of 50 mg (down from 100) - i seriously had almost no side effects. The only things i experienced were: 1) very odd, vivid dreams 2) some night sweats 3) first 2 days some zapping in hands and legs with a little numbness - went away completely after 2 days today is the first day with no pristiq altogether. Again no side effects (so far) except the same zapping and numbness i had when i dropped from 100 to 50. I assume the next few days will be the test. I was advised to go to one 50mg every tother day for another 2 weeks but i may just cut off completely now, i don't think I'm too p...
Updated 4 days ago.
Tapering dosage pristiq
1 Reply RSS Share
I have been on pristiq for about 8 years. I'm at 100 mg and have been for some time. I want to drop to 50. Does anybody have experience with this? Also, I have started losing hair after having a full head of nice hair. I know it's due to the pristiq and/or Wellbutrin (buspirone) I take. Can anybody relate? ## Most medications that have an effect on your body chemistry can cause hair loss, according to FDA reports. You may also experience nausea, dizziness, headache mood changes, and weight changes. Why are you wanting to lower your dosage? What condition was it prescribed to treat? Are you on any other medications?
Updated 12 days ago.
Pristiq Night Sweats
7 Replies RSS Share
Hi all, I have been on Pristiq for 5+ years. Soon after I began, I started dealing with night sweats. Not just mild sweat - I'm talking my PJs and sheets are drenched. It is awful! The night sweats have come and go over the years but are currently very bad. I can't seem to get much information on the internet about this side effect being an issue for many people. Has anyone else experienced night sweats from taking Pristiq? ## Hi Erin, According to the manufacturer, sweating is actually one of the most common side effects people experience from taking Pristiq (Desvenlafaxine). However, happens to list "sweating" as both a 'general' and 'serious' side effect here: Have you already made your doctor ...
Updated 16 days ago.
Pristiq Withdrawal (waking nightmare)
1 Reply RSS Share
I have been taking 150 mg of Pristiq for over 5 years. As of 5 days ago, I have completely weened off the drug (with support from a psychiatrist). I have a lot of the common side effects (fatigue, dizziness, "brain zaps", agitation, depression, suicidal thought, nightmares); however, I also feel delusional. It's hard to describe because of how subtle it is. Essentially, everything around me feels amiss. I apologize for the dramatic description, but it's like the feeling of my nightmares is transcending to my waking life. I don't know how else to describe it. I feel like I'm living in a nightmare. Has anyone else experienced something like this? It is agonizing and disturbing. ## Hello, Daniel! How are you doing? Yes, I have! Not with Pristiq, since I've never...
Updated 18 days ago.
Pristiq tapering experience
6 Replies RSS Share
I was on Pristiq for nearly four years to help stabilize my mood (50mg). The drug was fantastic in achieving the result I was looking for and really gave me the space in my head to come to terms with my issues and time to reflect. The side effects for me were weight gain (15kg) and loss of libido but overall a small price to pay. I decided in December to come off the drug and read as much information as I could find, both professional and user opinion. I spoke with my doctor initially and his advice was to take the medication on alternate days. I chose to ignore that advice based on the way I felt if I missed a day and reading others experiences. Against manufacturers advice I decided to cut the tablet and reduce my dose a quarter at a time. To start with I spoke with my family to make ...
Updated 21 days ago.
Weaning off pristiq
432 Replies RSS Share
I just wanted to tell all of you trying to get off pristiq, its possible. I was on pristiq for severe panic attacks for 6 months. It saved my life. It gave me a chance to slow down my career, gave me a huge wakeup call. This drug put a cloud over my brain. I was not my happy, fun loving self. I was like a step ford wife. You cant wean off this pill. I was on 50mg. I did every other day for a month. Every third day for two weeks then cold turkey. It really was not so bad. I layer on my couch for three days, cried a bit and watched movies. I'm happily on all holistic medications, no longer a slave to pristiq. If I can beat anxiety, anyone can. My biggest advice.. Exercise. Next, surround yourself with positive people. Three, talk out your problems. Good luck. ## Fantastic advice and v...
Updated 1 month ago.
What is Desvenlaflax
14 Replies RSS Share
I've been taking Pristiq for a long time, understanding there was no generic. I've even spoken to my Dr who prescribed it about a generic not having been released. Today I changed pharmacies, having provided them with my last bottle of Pristiq for all the info. I was given Desvenlaflax, showing it was generic for Pristiq. I'm confused. I'd like to know if this is actually the generic. I'm familiar with Desvenlafaxine but never heard of what I've now been given. Also I know some generics are not as effective as the brand name. If you have any information concerning the efficacy, please provide. ## That is Desvenlafaxine, they just abbreviated it on this refill. The only way to see how it will work for you is by trying it to see. The FDA lists the typical side effe...
Updated 1 month ago.
135 Replies RSS Share
atrial fibrillation ## Pristiq, which contains the active ingredient Desvenlafaxine, is an antidepressant. Some of the most common side effects include: nausea, drowsiness, sexual dysfunction and constipation. ## For 18 years I have been taking Prozac. Each time I have attempted to change, under the care of a physician, I've touched the bottom of depression again. During the last several years my dosage has been upped to 40 mg in the AM and 40 in the PM. I've suffered anxiety, expecially upon awakening in the morning. In the last 10 years I've been divorced from a man with passive-aggressive tendancies. I go to a well reputed psychologist,exercise and eat well. I regularly meditate and do daily journaling,etc. I'm now married to a good person. My psychologist, chiropract...
Updated 1 month ago.
Tingling And Numbness In My Hands And Feet
2 Replies RSS Share
I have tingling and numbness in my hands and my feet muscles hurt. I am on Pristiq, but it has only been a week. Before that, i was on paxil for concentration and it worked, however now this has come about and i take vicodin for pain, which does help somewhat. ## Pristiq contains the active ingredient Desvenlafaxine, which is an SNRI class antidepressant, these have also been shown to help some people with certain forms of nerve pain, however, it will take about 4 to 6 weeks to reach its full effectiveness in your body. Side effects may include: nausea, drowsiness, weight gain and dry mouth. Learn more: Vicodin contains the active ingredients Hydrocodone and Acetaminophen, it is a narcotic pain reliever. Side effects may include: nausea, dizziness, constipation and dry mouth. Learn mo...
Updated 2 months ago.

Possible Dosages for this and Related Drugs:

Desvenlafaxine Succinate
  • Tablet: 100mg, 50mg
  • Tablet, Extended Release: 100mg, 25mg, 50 Mg. And 100 Mg., 50mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Pristiq: (6 results)

Sorted by National Drug Code
  • 0008-1211 24 Hr Pristiq 50 mg Extended Release Tablet by Wyeth Pharmaceuticals Inc., a Subsidiary of Pfizer Inc.
  • 0008-1222 24 Hr Pristiq 100 mg Extended Release Tablet by Wyeth Pharmaceuticals Inc., a Subsidiary of Pfizer Inc.
  • 35356-491 24 Hr Pristiq 50 mg Extended Release Tablet by Lake Erie Medical & Surgical Supply Dba Quality Care Products LLC
  • 35356-567 24 Hr Pristiq 100 mg Extended Release Tablet by Lake Erie Medical Dba Quality Care Products LLC
  • 54868-2932 24 Hr Pristiq 50 mg Extended Release Tablet by Physicians Total Care, Inc.
  • 55154-4230 24 Hr Pristiq 50 mg Extended Release Tablet by Cardinal Health

Other drugs which contain Desvenlafaxine Succinate or a similar ingredient: (3 results)

Related Pristiq Topics:

pristiq and weight gain
I started pristiq approx 5 weeks ago and altho my doctor assured me that it was a weight neutral drug I have easily gain... 74 replies
This is NOT a good medicine. I felt more depressed on it and had several side effects, nausea, lack of appetite, dizzine... 44 replies
pristiq for depression and anxiety did not work
My Son went to the Dr. for anxiety and depression, pristiq created more problems for him, panic attacks, insomnia, loss ... 13 replies
Pristiq an Libido- Advice Needed!
I have been taking Pristiq for about 3 years now due Anxiety attacks. After taking the drug for afew days I had the wors... 8 replies
Pristiq Night Sweats
Hi all, I have been on Pristiq for 5+ years. Soon after I began, I started dealing with night sweats. Not just mild swea... 7 replies
Pristiq tapering experience
I was on Pristiq for nearly four years to help stabilize my mood (50mg). The drug was fantastic in achieving the result ... 6 replies
pristiq is it a narcotic
is pristiq a narcotic I NEED TO KNOW ## Hello, Joe! How are you? No, Pristiq contains the active ingredient Desvenlafaxi... 5 replies
pristiq withdrawl
Hi all, I was on 150 of pristiq and have been tapering off for two months. Last week I went from 50 to 25 for about 4 da... 5 replies
Pristiq Withdrawls
I have been on Pristiq for about 4 years and was on levoxyl for a few years prior. I had started taking Sarafem 925mg) a... 4 replies
Pristiq and hot flushes/flashes
I have been on this for 5 days. The last 3 days I have been having hot flushes and they have been getting more frequent.... 4 replies

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