Active Ingredient(s):Tolbutamide FDA Approved: * May 31, 1957 Pharm Company: *PHARMACIA AND UPJOHN Category:Diabetes
Tolbutamide is a first-generation potassium channel blocker, sulfonylurea oral hypoglycemic medication. This drug may be used in the management of type 2 diabetes if diet alone is not effective. Tolbutamide stimulates the secretion of insulin by the pancreas.
It is not routinely used due to a higher incidence of adverse effects compared to newer, second-generation sulfonylureas, such as Glibenclamide. It generally has a short duration of action due to its rapid metabolism, so is safe for use ...
* May have multiple approval dates, manufacturers, or labelers.