Active Ingredient(s): Danaparoid
FDA Approved: * December 24, 1996
Pharm Company: * ORGANON USA INC
Category: Blood Thinner (Anticoagulant)

Danaparoid sodium (Orgaran) is an anticoagulant[1] with an antithrombotic action due to inhibition of thrombin generation (TGI) by two mechanisms: indirect inactivation of Factor Xa via AT and direct inhibition of thrombin activation of Factor IX (an important feedback loop for thrombin generation). It also possesses a minor anti-thrombin activity, mediated equally via AT and Heparin Co-factor II producing a ratio of anti-Xa:IIa activity >22. [Meuleman DG. Haemostasis 1992;22:... [wikipedia]

* May have multiple approval dates, manufacturers, or labelers.