Active Ingredient(s): Macitentan
FDA Approved: * October 18, 2013
Category: Blood Pressure

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Opsumit Overview

Macitentan, sold under the brand name Opsumit, is an endothelin receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH).[2] The other two ERAs marketed as of 2014 are bosentan and ambrisentan.[2] Macitentan is a dual ERA, meaning that it acts as an antagonist of two endothelin (ET) receptor subtypes, ETA and ETB.[2] However, macitentan has a 50-fold increased selectivity for the ETA subtype compared to the E...

Read more Opsumit Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Macitentan

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Possible Dosages for this and Related Drugs:

  • Tablet: 10mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Opsumit: (1 result)

Sorted by National Drug Code
  • 66215-501 Opsumit (Macitentan 10 mg) by Actelion Pharmaceuticals Us, Inc.

Other drugs which contain Macitentan or a similar ingredient: (1 result)