Active Ingredient(s): Neratinib Maleate
FDA Approved: * July 17, 2017
Pharm Company: * PUMA BIOTECH
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Nerlynx Overview

Neratinib (INN; trade name Nerlynx; development code HKI-272)[1] is a tyrosine kinase inhibitor anticancer drug.[2] Pharmacology Like lapatinib and afatinib, it is a dual inhibitor of the human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.[3][4] It inhibits them by covalently binding with a cysteine side chain in those proteins.[5] Neratinib has an IC50 of 59 nM against HER2 and shows weak inhibition against KDR and Scr with IC50 values of 0....

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Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

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Possible Dosages for this and Related Drugs:

Neratinib Maleate
  • Tablet: 40mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Nerlynx: (1 result)

Sorted by National Drug Code
  • 70437-240 Nerlynx 48.31 mg Oral Tablet by Puma Biotechnology, Inc.

Other drugs which contain Neratinib Maleate or a similar ingredient: (1 result)

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