Nerlynx OverviewNeratinib (INN; trade name Nerlynx; development code HKI-272) is a tyrosine kinase inhibitor anticancer drug. Pharmacology Like lapatinib and afatinib, it is a dual inhibitor of the human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases. It inhibits them by covalently binding with a cysteine side chain in those proteins. Neratinib has an IC50 of 59 nM against HER2 and shows weak inhibition against KDR and Scr with IC50 values of 0....
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Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Neratinib
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Possible Dosages for this and Related Drugs:
- Tablet: 40mg
NDC Database Records for Nerlynx: (1 result)Sorted by National Drug Code
- 70437-240 Nerlynx 48.31 mg Oral Tablet by Puma Biotechnology, Inc.