Active Ingredient(s): Mechlorethamine, Nitrogen Mustard
FDA Approved: * March 15, 1949
Pharm Company: * OVATION PHARMS
Category: Cancer

Chlormethine (INN, BAN), also known as mechlorethamine (USAN, USP), mustine, HN2, and (in post-Soviet states) embikhin (), is a nitrogen mustard sold under the brand name Mustargen among others. It is the prototype of alkylating agents, a group of anticancer chemotherapeutic drugs. It works by binding to DNA, crosslinking two strands and preventing cell duplication. It binds to the N7 nitrogen on the DNA base guanine. As the chemical is a blister agent, its use is strongly restricted within t... [wikipedia]

* May have multiple approval dates, manufacturers, or labelers.
1 Discussion

Dosage List

Mustargen 10 mg/10ml Intracavitary; Intravenous Powder, for Solution
NDC: 55292-911
Recordati Rare Diseases, Inc.

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