Muromonab-CD3

Category: Immunosuppressive

Muromonab-CD3 (trade name Orthoclone OKT3, marketed by Janssen-Cilag) is an immunosuppressant drug given to reduce acute rejection in patients with organ transplants.[1][2] It is a monoclonal antibody targeted at the CD3 receptor,[3] a membrane protein on the surface of T cells. It was the first monoclonal antibody to be approved for clinical use in humans.[2] Contents 1 History 2 Indications 3 Pharmacodynamics and chemistry 4 ... [wikipedia]

Dosage List

Okt3 5 mg/5ml Intravenous Injection, Solution
NDC: 59676-101
Labeler:
Centocor Ortho Biotech Products, L.p.

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