Multihance MultipackActive Ingredient(s): Gadobenate Dimeglumine
FDA Approved: * November 23, 2004
Pharm Company: * BRACCO
Category: Diagnostic Aid
Gadobenic acid (INN, brand name Multihance) is a complex of gadolinium with the ligand BOPTA. In the form of the methylglucamine salt meglumine gadobenate (INNm) or gadobenate dimeglumine (USAN), it is used as a gadolinium-based MRI contrast medium. BOPTA is a derivative of DTPA in which one terminal carboxyl group, –C(O)OH is replaced by -C–O–CH2C6H5. Thus gadobenic acid is closely related to gadopentetic acid. BOPTA itself was first synthesized in 1995.&... [wikipedia]* May have multiple approval dates, manufacturers, or labelers.