Category: Anesthetic

Methoxyflurane Overview

Methoxyflurane, marketed as Penthrane, Metofane, and Penthrox, is a halogenated ether that was in clinical use as a volatile inhalational anesthetic from its introduction in 1960 until the late 1970s. It was first synthesized in the late 1940s by William T. Miller and his team of chemists following their involvement in the Manhattan Project.[1] Methoxyflurane is an extremely potent and highly lipid-soluble anesthetic agent, characterized by very slow induction (onset of action...

Read more Methoxyflurane Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

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Hi I am wondering if Methoxyflurane can be used alongside nitrous oxide simultaneously. The nitrous oxide alone often is not as effective in achieving therapeutic dosage with adults and I wondered how the two may work. What clinical ill effects would be seen if a combination as such was actually used. Thanking you, Anand ## I do not know the answer to your question, however, if you are using Nitrous Oxide, even just once, you should be aware of the possibility of Nitrous Oxide Side Effects, particularly in that they reduce Vitamin B12 levels, which can lead to severe and even deadly problems. Preventing these side effects is as easy as supplementing with Vitamin B12 before and after procedures that use nitrous oxide- something that dentists never choose to do.


Possible Dosages for this and Related Drugs:

  • Liquid: 99.9%, 99.90%
  • Solution: 0.6mg/kg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Methoxyflurane or a similar ingredient: (1 result)

Related Methoxyflurane Topics:

It is use as inhaler analgesic in Emergency department. ## Yes, Methoxyflurane is an inhaled anesthetic, though it is no... 1 reply

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