Category: Genetic Disorders

Lumacaftor-Ivacaftor Overview

Lumacaftor/ivacaftor (brand name Orkambi) is a combination drug available as a single pill that is used for the treatment of cystic fibrosis in people who have two copies of the F508del mutation in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. It is a combination drug that consists of lumacaftor and ivacaftor. Ivacaftor increases the activity of the CFTR protein at the surface of epithelial cell, while lumacaftor acts as a chaperone during protein...

Read more Lumacaftor-Ivacaftor Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Lumacaftor-Ivacaftor Forums:

Be the first to start a discussion about this drug.

Possible Dosages for this and Related Drugs:

  • Granule: 100mg + 125mg, 125mg/packet + 100mg/packet, 150mg + 188mg, 188mg/packet + 150mg/packet
  • Tablet: 125mg + 100mg, 125mg + 200mg, 200mg/125mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Lumacaftor-Ivacaftor or a similar ingredient: (1 result)

Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 23 January 2019.

We are committed to your privacy.

Copyright © 2005-2019 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA