Lumacaftor-Ivacaftor OverviewLumacaftor/ivacaftor (brand name Orkambi) is a combination drug available as a single pill that is used for the treatment of cystic fibrosis in people who have two copies of the F508del mutation in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. It is a combination drug that consists of lumacaftor and ivacaftor. Ivacaftor increases the activity of the CFTR protein at the surface of epithelial cell, while lumacaftor acts as a chaperone during protein...
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Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Lumacaftor/ivacaftor
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Possible Dosages for this and Related Drugs:
- Granule: 100mg + 125mg, 125mg/packet + 100mg/packet, 150mg + 188mg, 188mg/packet + 150mg/packet
- Tablet: 125mg + 100mg, 125mg + 200mg, 200mg/125mg
Other drugs which contain Lumacaftor-Ivacaftor or a similar ingredient: (1 result)
- ORKAMBI Lumacaftor + Ivacaftor