Harvoni

Active Ingredient(s): Ledipasvir + Sofosbuvir
FDA Approved: * October 10, 2014
Pharm Company: * GILEAD SCIENCES INC
Category: Hepatitis

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Harvoni Overview

Ledipasvir is a drug for the treatment of hepatitis C that was developed by Gilead Sciences.[1] After completing Phase III clinical trials, on February 10, 2014 Gilead filed for U.S. approval of a ledipasvir/sofosbuvir fixed-dose combination tablet for genotype 1 hepatitis C.[2][3] The ledipasvir/sofosbuvir combination is a direct-acting antiviral agent that interferes with HCV replication and can be used to treat patients with genotypes 1a or...

Read more Harvoni Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Ledipasvir

Recent Harvoni Forums: RSS Feed

long term side effects of harvoni

I had Harvoni treatment last spring. I am not the same. My nervous system is a wreck. My anxiety problems have increased, depression and lack of motivation. My eyes changed drastically. My thoughts are not focused, I am nervous all the time, can focus or sleep. I had a 2 month migraine. Ringing in the ears is intense. I also was on pigalated interferon and ribivirn, I was pulled off mid treatment because I got so sick. After that treatment, I also had long term side effects. There isn't any back support for post harvoni people, nor are their anyone specializing in the after effect of long term HCV infection, it is NOT just a liver disease, it effects the nervous system and all else. I am at a loss for support with the doctors in my area, none seem to want to do any research and they...

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Harvoni post treatment

I'm done now and finished 12 week tx 4/14/15 and I can say back pain, neck pain and pain in the legs is now a part of it for me. I was dealing with the head aches and sick feeling. Still feel sick and fatigued with joint ache. Hoping all of this stops soon. I'm tired of being sick ## Hello, Mike! How are you? Those are all typical side effects of Harvoni, as reported by the FDA and other users. They should improve with time, now that you've finished your course of treatment with it. Other side effects may also include diarrhea and insomnia. How well did it work for you? It seems that many have had good results with it. ## I was wondering if your joint pain has gone away . I am 55 in good shape and all my labs are normal except viral loan shows 1mm and slightly elevated enzym...

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Harvoni side effects for my wife - concerned husband

Hi my wife has just started harvoni - about 9 days or so now - and she is getting swelling in left leg and also feels like there is pressure in her head. Anyone else have anything similar? Thanks ## Hello, Chris! How is your wife doing? Has there been any change? It has been known to cause headaches, according to the FDA, but the edema is unusual. Other typical side effects may include nausea, diarrhea and insomnia. Is the only medication that she is on? She should likely have this checked out by her doctor. ## Hello. I took Harvoni for 12 weeks, 6 months ago. I had the weird pressure in my head also. It continued on and off thru treatment. It was a pressureb headache. It went away soon as I finished the meds. I also have swelling in both my feet and ankles. Its related to me being a 55...

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Harvoni side effects

I have been taking Harvoni for 3 months now and am having nerve pain in my legs and lower back pain. Is anyone else taking Harvoni having any of these same side effects as me? Please help if you are able. Thank you ## Hi Tony, From what I've researched, "lower back pain" is specifically listed as one of the more common side effects of Sofosbuvir (the second active ingredient in Harvoni); so I'd imagine that "leg pain" may be attributed to this drug as well. If you'd like a more concrete reference, "back pain" is also listed as a side effect of Sofosbuvir on Pubmed at: ncbi.nlm.nih.gov/pubmed/25422576 That said, you may want to contact your doctor if the pain becomes too bothersome or severe. This way you and your doctor can determine if Harvoni is sti...

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Hep c treatment using Harvoni medication

I have cirrosis and hep c. My doctor has put me on a 12 week course of Harvoni. I finish my treatment in 3 days and then am off for my blood test. The results of my first blood test show significant improvement. I read a lot of other people's experiences who have been on this treatment. A lot I've read say after there 1st blood test (4 weeks on treatment ) that they have already been cured. I'm feeling quite down that my results don't show this for me. While deciding my treatment, my doctor kept changing his mind of the length of time to be on treatment (12 weeks or 24 weeks).he decided on 12 weeks in the end. He's accidentally given me 1 extra repeat. My 12 weeks is up in a few days and I'm thinking of getting it, so I'll be on it for 16 weeks and not tell h...

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Post Harvoni Reduced Immunity

I finished 8 weeks of Harvoni on April 8 and labs said HCV is undetected. My question is has anyone heard of "post-Harvoni reduced immunity" I came down with a bad case of the flu and doc thinks Harvoni may have caused reduced immunity. Any insights? ## Hi Sam, I have yet to come across any specific details on post-Harvoni immunity. However, in order to reach an accurate conclusion one must also take into consideration some other things that can impact one's level of immune function, such as: environmental factors, diet, mental/emotional health, etc, during and after the time frame of treatment. Not sure if Harvoni is available in inj. form like similar medications are, but just as a side note - there was a study done by Rockefeller University, suggesting that the act of adm...

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Post Harvoni 2 months & still feeling intermittent symptoms

I get fatigue and brain fog but not nearly as severe as with hep and less frequent also itching all over continues intermittently. Anyone got a clue re; these issues, the Dr, just kinda says 'duh'. ## @Blipette, Sorry to hear that you're still experiencing symptoms 2 months after stopping Harvoni. I hear about this sort of thing happening with other types of medications as well, so personally, I don't think it's very unusual. Probably quite frustrating more than anything, being that it's taking so long to leave your body. I really feel for you. From what I've researched, the half life of ledipasvir (one of the primary active ingredients in Harvoni) is right around 47 hours. It's hard to know how much of this medication might've accumulated (overlappin...

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Side effects for Harvoni

Started 3 weeks ago. First 3 days I got tired... but was taking it at 7pm so it worked out great. No side effects at all now! Very happy and looking forward to my first doctor visit to see how much the viral load has dropped. Stay WELL hydrated...I drink at least 8 bottles of water each day and many say it helps. Best of luck to everyone! ## Hello Pop pop! How are you doing? Has there been any change? As to your fluid intake, please be careful, there is such a thing as too much! While many people think you need to drink 8 glasses of water a day, that should actually be your overall fluid intake, not just water, so it should include juices, coffee, sodas and etc....including the liquid in the foods you eat. I just wanted to add this as precautionary note, since taking in too much fluid h...

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post harvoni weight gain

Having a big problem with weight gain, post Olysio/Solvaldi 12-wk. tx, and 26-wk Harvoni tx. Clear for two years. Is anyone else experiencing this? I'm getting so tired of my doctors telling me to diet, exercise, and drink water. I'm doing that. Exercise is hard because of the edema in my legs, ankles, and feet. Suggestions? Will be seeing my liver specialist May 18th. Thanks. ## Have you tried seeing your specialist sooner? It is hard to say what might be causing such an issue, if you're done taking the medication. How long ago did you finish your course of treatment with it? The FDA and most patients list the typical side effects as possibly including nausea, dizziness, headache, and joint pain. Are you currently on any other medications? How much have you gained? How bad ...

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Harvoni withdrawal symptoms

anyone having problems after stopping harvoni? ## Hello, Kat! How are you? What type of symptoms are you experiencing? I'm not seeing anything about it causing withdrawal symptoms, but it is a relatively new drug. Its typical side effects, as listed by the FDA, may include nausea, diarrhea, headache and weakness. Withdrawal effects would usually be virtually opposite, so may include constipation, dizziness and drowsiness. How long were you on it? ## Hello, I also am having withdrawel feelings, I am constantly tired, I feel fatiqued, slight head ache, have a sick feeling in my stomach I completed the the Harvoni treatment, I pretty much had these same feelings on the Harvoni. I saw my doctor 2 weeks ago, he had me do some blood work, I go back this morning to see him, I hope he has s...

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Possible Dosages for this and Related Drugs:

Ledipasvir + Sofosbuvir
  • Pellets: 33.75mg + 150mg/packet, 45mg + 200mg/packet
  • Tablet: 45mg + 200mg, 90mg + 400mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Harvoni: (1 result)

Sorted by National Drug Code
  • 61958-1801 Harvoni Oral Tablet, Film Coated by Gilead Sciences, Inc

Drugs with one or more similar ingredients: (7 results)

Related Harvoni Topics:

Harvoni side effects
I have been taking Harvoni for 3 months now and am having nerve pain in my legs and lower back pain. Is anyone else taki... 714 replies
Harvoni side effects for my wife - concerned husband
Hi my wife has just started harvoni - about 9 days or so now - and she is getting swelling in left leg and also feels li... 57 replies
Harvoni withdrawal symptoms
anyone having problems after stopping harvoni? ## Hello, Kat! How are you? What type of symptoms are you experiencing? I... 52 replies
Harvoni treatment side effects
Curious, I've started my 5th week of treatment and am wondering if anyone has experienced similar side effects as me... 51 replies
Harvoni treatment
Hello, I am Hans (71 years). I live in Germany. I've been taking Harvoni for 6 weeks. I am happy that I have no prob... 16 replies
Harvoni and tired
HEP C =tired..Harvoni = tired. approx. 6 weeks into my harvoni treatment and every day I NEED a afternoon nap of one to ... 10 replies
Harvoni and headaches
I have started a 12 wk program of Harvoni this is day 4 ,, Iam having head aches they come and go but are never far away... 7 replies
Harvoni post treatment
I'm done now and finished 12 week tx 4/14/15 and I can say back pain, neck pain and pain in the legs is now a part o... 4 replies
harvoni post 3 months
I am going crazy. I have never felt right on this. I was 24 weeks on Harvoni, and had been bedridden since then due to m... 3 replies
Harvoni for Hepatitis c
Im halfway through a 12 week course and am exhausted for no reason.... I have only been sick twice from the drug but oth... 2 replies




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