Efudex

Active Ingredient(s): Fluorouracil, 5-FU
FDA Approved: * July 29, 1970
Pharm Company: * VALEANT PHARM INTL
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Efudex Overview

Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer.[2] By intravenous injection it is used for treatment of colorectal cancer, oesophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer.[2] As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts.[3][4] Side effects of use by injection are common.&...

Read more Efudex Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Fluorouracil

Recent Efudex Forums: RSS Feed

Efudex 5%

Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swelling or any sign of side effects. Does this mean the spot on my lip is non-cancerous? I was under the impression I was to have swelling and pain, and that this cream kills everything allowing the good cells to regrow. ## have to start the efudex 5% cream once a day on upper and lower lips. I am extremely worried about the pain. Is there anything besides aquafor or Vaseline to he help with pain? ## It contains the active ingredient fluorouracil, which is used to treat areas of skin that have been heavily exposed to the sun, or those that have been tested to have Basal Cell Carcinoma. The FDA lists its typical side effects as possibly including skin redness, irritation,...

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Headaches with Efudex treatment

I am on Day 30 of Efudex treatment on the top of my nose and a small area on my chest. I stopped the cream on Day 28 as the skin was starting to erode. I've had headaches the past two weeks that won't go away with ibuprofen, Goody's headache powders, tylenol... nothing. It's caused me to generally feel like crap. Anyone else have these headaches? ## Headaches are a possible side effect of Effudex, according to FDA reports, other side effects may include skin burning, dizziness, chills, and nasal irritation. How long has it been since you stopped using it, now? Has there been any change? Have you informed your doctor of the problem? ## Headaches are common apparently, as is nausea and other gastric issues. And they can vary a lot between individuals. Serious side-effects ...

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The 3-week Efudex / Fluorouracil nightmare is now unnecessary!!

Harvard Medical recently discovered a new treatment regime for AK. This new four-day Harvard Medical protocol is going to save us all from the Efudex & Fluorouracil nightmare: Adding calcipotriene to 5-FU dramatically reduced AKs I used this 4-day treatment for AK in Dec '18 and it works!! Save yourself from the 3 week fluorouracil nightmare and do this 4-day treatment instead. I made this Youtube video of my experience with this protocol: The treatment resolves actinic keratosis in only 4 days. No longer is the pain and discomfort of the commonly prescribed 3 week Flouracil necessary to clear your skin of these pre-cancerous lesions. Mix 5% Fluoroucil and Calcipotriene 50/50 and apply twice per day for four days. Both of these creams can be purchased through prescription. Your ...

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Efudex doesn't have to be a nightmare

I was prescribed Efudix to treat spots on the back of my hands. I have been applying a thin layer daily for 4 weeks. I have had no side effects, no irritation, burning sensations, blistering or pain. The spots have become slightly redder and that's all. Efudix does not have to a nightmare and every case is different. ## That is correct, we are all different, so not everyone will experience side effects while using it. The typical side effects may include skin redness, burning, sun sensitivity, and swelling. Are you still experiencing good results with it? ## Hi. I will touch base with you again early next week. I am meeting the skin doctor on Monday to get their opinion. Still little or no change after 6 weeks. The Pharmacist has suggested twice daily application but I will be guide...

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A Lighter Fluorouracil/Calcipotriene Combo?

I've just completed 10 days of fluorouracil + calcipotriene/calcipotriol treatment - in my case, being in México, branded Efudix + Diavonex rather than Efudex + Dovonex - and one of the most annoying parts of it was that the combo cream is so thick (and greasy). It drags painfully against the affected skin and is the worst part of the procedure in my opinion; the duration and severity of the reaction is way less than using fluorouracil on its own, which is a big advantage, but my question is, is there a "lighter" version of these creams? Or, ideally, a solution/lotion? Actually, I know there is a fluorouracil lotion for scalp use, but you'd need a lotion version of the calcipotriene as well to mix properly I'd guess, and I have not been able to find this. Anyway...

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Efudex-40 (fluorouracil)

Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this crazy? ## Not really. It is listed in the drug monograph that it can be used topically to treat certain cancerous or possibly cancerous conditions. ## Has anyone used it on their lips? Won't it just keep bleeding non-stop? ## Heidi- I've used it on my lips three times. Each time it was an application morning and at bedtime. Though about the second week it gets very sensitive and blister-like lesions appear that means it's working. I applied a product called Acquafor (like Vaseline Jelly) to seal it and protect). The healing takes some time but the outcome is worth it. ## I just used Efudex for 2 weeks on lower lip. from day 7 blistered and ulcerated and wept...

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Efudex "Improved Formula"??

I am scheduled to start Efudex Nov. 2 and am apprehensive based on a friend's bad experience and other things I've read. My Dr. said that things have improved dramatically within the last year with a better formula. He said I will use the cream twice daily for 5 days, then he will see me to place a neutralizer on my face, and then I will heal the 2nd week; reducing the experience from a 4 to 2 week timeframe. Has anyone else heard of this or experienced this? ## Hello, Gina! How are you? What type of bad experience did your friend have? As to an improved formula, that might be true, but the active ingredient that could cause any side effects remains the same, so the FDA still lists them as possibly including skin redness, flaking, itching, and peeling. It isn't really a neut...

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Applying efudex to my face and how often to shave

I am applying efudex to my face. I usually shave every 2 days. Should I shave everyday so that my facial hairs do not interfere with spreading the cream on my face? ## I shaved once (with hair clippers, just to short stubble) before I started treatment, then 4 days later before I "lit up", figuring that I probably wouldn't be able to do it later on. I don't think the hair is an issue for application as much as trying to shave with a badly irritated face would be! I haven't used a blade shaver for years and would never try that while undergoing this treatment. Ouch! (I'm not a doctor, just a fellow sufferer.) Having said that, after I discovered - here - the fluorouracil/calcipotriol combo treatment, I swapped to that after day 3 of Efudex/Efudix-only. So I won...

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Efudex 5% and Silkis 3

My new dermatologist has prescribed a one-week per month treatment over four months, applying Silkis 3 in the morning and Efudex 5% at bedtime. I have used Efudex before in one spot, with the expected itching and scabs. What happens when I apply these creams all over my face and scalp, which don't have many particular keratosis spots? My job involves working with the public. ## My dermatologist prescribed Efudex and Desonide last week! Beginning tonight... 7 days Efudex and Desonide am and Desonide pm, followed by Desonide twice a day for 3 days, then stop for 3 weeks. Repeat 4 times after that ! ## How did this protocol work for you? Do you react quickly. How soon did the redness go away? I’m using a Efudex and a synthetic D3 derivative gel called Calcipotriol. I mix them 50-...

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Efudex with Dovonex

Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50% Dovonex (vitamin D) and it was very fast and easy. Four days of application of the combo "lit up" my face and 7 days later my face and scalp were virtually back to normal. Minimal pain, like a sunburn, and no scabbing, pus, etc. I was really scared to do the longer treatment after reading blogs and looking at pictures, but the new treatment is a piece of cake. Plus, according to related articles, it actually works better. A real win-win! "SCOTTSDALE, ARIZ. – A four-day topical combination regimen of 5-fluorouracil (5-FU) and calcipotriene removed almost 90% of facial actinic keratoses – significantly more than with 5-FU monotherapy, in a rando...

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Possible Dosages for this and Related Drugs:

Fluorouracil, 5-FU
  • Cream: 0.5%, 0.50%, 1%, 4%, 5%
  • Cream, Augmented: 4%
  • Injection: 50mg/ml
  • Solution: 1%, 2%, 5%
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Efudex: (1 result)

Sorted by National Drug Code
  • 0187-3204 Efudex 2 g/40g Topical Cream by Valeant Pharmaceuticals International

Other drugs which contain Fluorouracil, 5-FU or a similar ingredient: (5 results)

Related Efudex Topics:

Efudex-40 (fluorouracil)
Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this c... 27 replies
Efudex with Dovonex
Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50... 13 replies
Efudex 5%
Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swe... 12 replies
Efudex on scalp - side effects on hair?
Has anyone used Efudex on their head? I'm interested in any side effects on hair deterioration or loss. ## Hello Hoo... 6 replies
Efudex doesn't have to be a nightmare
I was prescribed Efudix to treat spots on the back of my hands. I have been applying a thin layer daily for 4 weeks. I h... 4 replies
Efudex treatment effects
I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What shou... 4 replies
Efudex 5% and Silkis 3
My new dermatologist has prescribed a one-week per month treatment over four months, applying Silkis 3 in the morning an... 3 replies
efudex40 application instructions
how and when should I apply efudex to my face? ## This is a drug used to treat certain types of cancer. How often and ho... 3 replies
Efudex-40
How to use and side efects ## please give me detailed description of how to apply and how long to apply efudex-40 ## I w... 3 replies
Efudex "Improved Formula"??
I am scheduled to start Efudex Nov. 2 and am apprehensive based on a friend's bad experience and other things I'... 2 replies