Efudex

Active Ingredient(s): Fluorouracil, 5-FU
FDA Approved: * July 29, 1970
Pharm Company: * VALEANT PHARM INTL
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Efudex Overview

Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer.[2] By injection into a vein it is used for colon cancer, esophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer.[2] As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts.[3][4] When used by injection most people develop side effects.[2] Common side...

Read more Efudex Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Fluorouracil

Recent Efudex Forums: RSS Feed

Flouracil and Calcipotriene combo reaction

I put this combo on face fro 5 days as prescribed. Pretty awful for 2 of the days but all clear after 2 weeks. HOWEVER, then I developed a bad rash on my chest - did not apply cream there. Doctor doesn't know but thinks maybe the absorbed cream went systemic. Cortisone helped. Now a similar rash has spread to my legs and arms. not burning but supper bumpy and itchy. Scrambling to find help. Has anyone experienced a systematic reaction to untreated parts of the body?

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Allergic reaction?

Used Efudex on back of my hand a year ago with little reaction. Had to use again & this time hand turned into Krakatoa! Scabs & weeping spread beyond immediate application site but understand this can happen. However, also have tiny pin head size blisters among & around the crusting with accompanying itching which I haven’t noted in other experiences on here & wonder if it’s an allergic reaction or part of the “process” & I just need to find something to ease the itching. Any advice really welcome as this time of use is becoming quite scarey ## While those can be normal side effects, it is always best to have your doctor check things out to be sure. Other side effects to Efudex may include skin color changes, swelling, and dryness (the last of...

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Efudex-40 (fluorouracil)

Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this crazy? ## Not really. It is listed in the drug monograph that it can be used topically to treat certain cancerous or possibly cancerous conditions. ## Has anyone used it on their lips? Won't it just keep bleeding non-stop? ## Heidi- I've used it on my lips three times. Each time it was an application morning and at bedtime. Though about the second week it gets very sensitive and blister-like lesions appear that means it's working. I applied a product called Acquafor (like Vaseline Jelly) to seal it and protect). The healing takes some time but the outcome is worth it. ## I just used Efudex for 2 weeks on lower lip. from day 7 blistered and ulcerated and wept...

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Treating wound after 12 weeks of Efudex

My wound is on my forearm & is about a 1 1/2” square. The skin is eroded and indented. Was told to use Neosphorin, keep covered & change bandages twice daily. Does this sound like good advice?

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Efudex 5% and Silkis 3

My new dermatologist has prescribed a one-week per month treatment over four months, applying Silkis 3 in the morning and Efudex 5% at bedtime. I have used Efudex before in one spot, with the expected itching and scabs. What happens when I apply these creams all over my face and scalp, which don't have many particular keratosis spots? My job involves working with the public. ## My dermatologist prescribed Efudex and Desonide last week! Beginning tonight... 7 days Efudex and Desonide am and Desonide pm, followed by Desonide twice a day for 3 days, then stop for 3 weeks. Repeat 4 times after that !

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Efudex with Dovonex

Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50% Dovonex (vitamin D) and it was very fast and easy. Four days of application of the combo "lit up" my face and 7 days later my face and scalp were virtually back to normal. Minimal pain, like a sunburn, and no scabbing, pus, etc. I was really scared to do the longer treatment after reading blogs and looking at pictures, but the new treatment is a piece of cake. Plus, according to related articles, it actually works better. A real win-win! "SCOTTSDALE, ARIZ. – A four-day topical combination regimen of 5-fluorouracil (5-FU) and calcipotriene removed almost 90% of facial actinic keratoses – significantly more than with 5-FU monotherapy, in a rando...

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The 3-week Efudex / Fluorouracil nightmare is now unnecessary!!

Harvard Medical recently discovered a new treatment regime for AK. This new four-day Harvard Medical protocol is going to save us all from the Efudex & Fluorouracil nightmare: Adding calcipotriene to 5-FU dramatically reduced AKs I used this 4-day treatment for AK in Dec '18 and it works!! Save yourself from the 3 week fluorouracil nightmare and do this 4-day treatment instead. I made this Youtube video of my experience with this protocol: The treatment resolves actinic keratosis in only 4 days. No longer is the pain and discomfort of the commonly prescribed 3 week Flouracil necessary to clear your skin of these pre-cancerous lesions. Mix 5% Fluoroucil and Calcipotriene 50/50 and apply twice per day for four days. Both of these creams can be purchased through prescription. Your ...

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Efudex, Dovonex and Desonide

My husband has been prescribed Efudex for 10 days (morning and evening on his scalp). Also, Dovonex twice daily and pop-Desonide twice daily (as needed). Which cream does he put on first, second...? Thank you.

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Efudex treatment effects

I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What should i do? ## Hello, Judy! How are you? Have you informed your doctor, yet? The U.S. FDA does list the dryness/crusting as being possible side effects of using it. It may also cause abdominal pain, headache and mouth sores. How long has your doctor instructed you to use it? ## Medline Plus states "If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil. If you are using fluorouracil to treat basal cell carcinoma, you should continue using it until the...

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Efudex 5%

Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swelling or any sign of side effects. Does this mean the spot on my lip is non-cancerous? I was under the impression I was to have swelling and pain, and that this cream kills everything allowing the good cells to regrow. ## have to start the efudex 5% cream once a day on upper and lower lips. I am extremely worried about the pain. Is there anything besides aquafor or Vaseline to he help with pain? ## It contains the active ingredient fluorouracil, which is used to treat areas of skin that have been heavily exposed to the sun, or those that have been tested to have Basal Cell Carcinoma. The FDA lists its typical side effects as possibly including skin redness, irritation,...

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Possible Dosages for this and Related Drugs:

Fluorouracil, 5-FU
  • Cream: 0.5%, 0.50%, 1%, 4%, 5%
  • Cream, Augmented: 4%
  • Injection: 50mg/ml
  • Solution: 1%, 2%, 5%
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Efudex: (1 result)

Sorted by National Drug Code
  • 0187-3204 Efudex 2 g/40g Topical Cream by Valeant Pharmaceuticals International

Other drugs which contain Fluorouracil, 5-FU or a similar ingredient: (5 results)

Related Efudex Topics:

Efudex-40 (fluorouracil)
Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this c... 25 replies
Efudex with Dovonex
Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50... 10 replies
Efudex 5%
Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swe... 8 replies
Efudex treatment effects
I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What shou... 4 replies
Efudex on scalp - side effects on hair?
Has anyone used Efudex on their head? I'm interested in any side effects on hair deterioration or loss. ## Hello Hoo... 3 replies
efudex40 application instructions
how and when should I apply efudex to my face? ## This is a drug used to treat certain types of cancer. How often and ho... 3 replies
Efudex-40
How to use and side efects ## please give me detailed description of how to apply and how long to apply efudex-40 ## I w... 3 replies
Efudex doesn't have to be a nightmare
I was prescribed Efudix to treat spots on the back of my hands. I have been applying a thin layer daily for 4 weeks. I h... 2 replies
Efudex (Fluorouracil) Cream 5%
I used this prescription on my forehead twice a day for 10 days. Removed all my ak's. Has now been about 1 year and ... 2 replies
Efudex 5% and Silkis 3
My new dermatologist has prescribed a one-week per month treatment over four months, applying Silkis 3 in the morning an... 1 reply




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