Efudex

Active Ingredient(s): Fluorouracil, 5-FU
FDA Approved: * July 29, 1970
Pharm Company: * VALEANT PHARM INTL
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Efudex Overview

Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer.[2] By injection into a vein it is used for colon cancer, esophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer.[2] As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts.[3][4] When used by injection most people develop side effects.[2] Common side...

Read more Efudex Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Fluorouracil

Recent Efudex Forums: RSS Feed

The 3-week Efudex / Fluorouracil nightmare is now unnecessary!!

Harvard Medical recently discovered a new treatment regime for AK. This new four-day Harvard Medical protocol is going to save us all from the Efudex & Fluorouracil nightmare: Adding calcipotriene to 5-FU dramatically reduced AKs I used this 4-day treatment for AK in Dec '18 and it works!! Save yourself from the 3 week fluorouracil nightmare and do this 4-day treatment instead. I made this Youtube video of my experience with this protocol: The treatment resolves actinic keratosis in only 4 days. No longer is the pain and discomfort of the commonly prescribed 3 week Flouracil necessary to clear your skin of these pre-cancerous lesions. Mix 5% Fluoroucil and Calcipotriene 50/50 and apply twice per day for four days. Both of these creams can be purchased through prescription. Your ...

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Efudex-40 (fluorouracil)

Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this crazy? ## Not really. It is listed in the drug monograph that it can be used topically to treat certain cancerous or possibly cancerous conditions. ## Has anyone used it on their lips? Won't it just keep bleeding non-stop? ## Heidi- I've used it on my lips three times. Each time it was an application morning and at bedtime. Though about the second week it gets very sensitive and blister-like lesions appear that means it's working. I applied a product called Acquafor (like Vaseline Jelly) to seal it and protect). The healing takes some time but the outcome is worth it. ## I just used Efudex for 2 weeks on lower lip. from day 7 blistered and ulcerated and wept...

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Efudex, Dovonex and Desonide

My husband has been prescribed Efudex for 10 days (morning and evening on his scalp). Also, Dovonex twice daily and pop-Desonide twice daily (as needed). Which cream does he put on first, second...? Thank you.

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Efudex treatment effects

I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What should i do? ## Hello, Judy! How are you? Have you informed your doctor, yet? The U.S. FDA does list the dryness/crusting as being possible side effects of using it. It may also cause abdominal pain, headache and mouth sores. How long has your doctor instructed you to use it? ## Medline Plus states "If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil. If you are using fluorouracil to treat basal cell carcinoma, you should continue using it until the...

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Efudex 5%

Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swelling or any sign of side effects. Does this mean the spot on my lip is non-cancerous? I was under the impression I was to have swelling and pain, and that this cream kills everything allowing the good cells to regrow. ## have to start the efudex 5% cream once a day on upper and lower lips. I am extremely worried about the pain. Is there anything besides aquafor or Vaseline to he help with pain? ## It contains the active ingredient fluorouracil, which is used to treat areas of skin that have been heavily exposed to the sun, or those that have been tested to have Basal Cell Carcinoma. The FDA lists its typical side effects as possibly including skin redness, irritation,...

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Help with pain while using Efudex cream

I am on week 5 of using Efudex just above my baby toe. Really hard to wear shoes so pretty housebound. The pain has been excruciating the last few days. Tried Tylenol, Tylenol 3 and Ibuprofen - and nothing works. Can anyone recommend something? ## It might be best to speak to your doctor to find out what might help you the most, and do so safely. Efudex has been known to cause some pain, redness, and irritation, to the treated area as side effects, along with itching, and darkening of the skin. Has there been any change? Are you on any other medications?

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Redness after Efudex treatment

I have used Efudex twice over several years. I wonder what will help the redness that happens after the crust has peeled away? The affected area is upper lip and side of nose. ## Hi Ren, have you finished taking the course of Efudex at this point? Medline Plus says "If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil." It also says that the redness is normal, except in cases of a severe red skin rash (which should be reported as a serious side effect). Would you consider your case severe? As to treating the redness, you may be able to apply an over the counte...

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Efudex doesn't have to be a nightmare

I was prescribed Efudix to treat spots on the back of my hands. I have been applying a thin layer daily for 4 weeks. I have had no side effects, no irritation, burning sensations, blistering or pain. The spots have become slightly redder and that's all. Efudix does not have to a nightmare and every case is different. ## That is correct, we are all different, so not everyone will experience side effects while using it. The typical side effects may include skin redness, burning, sun sensitivity, and swelling. Are you still experiencing good results with it? ## Hi. I will touch base with you again early next week. I am meeting the skin doctor on Monday to get their opinion. Still little or no change after 6 weeks. The Pharmacist has suggested twice daily application but I will be guide...

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Efudex (Fluorouracil) Cream 5%

I used this prescription on my forehead twice a day for 10 days. Removed all my ak's. Has now been about 1 year and a few are returning. You must apply a very thin film. It did turn bright red after about 7 days. Remains that way while peeling. About three weeks after stopping treatment. Not much pain for me. Just too much time hiding at home. Don't use any cosmetics while treating. Never do your whole face at once! ## I agree completely. I did the exact treatment in 2014 and have been using this product on and off since then. Only a few have returned to this day. Works great for me. I experienced minimum sting or itching. You must use a very fine touch of cream and then rub it in. Keep treated areas small. Never exceed over 9 x 9 inch or it will get into your blood and cause pa...

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Efudex with Dovonex

Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50% Dovonex (vitamin D) and it was very fast and easy. Four days of application of the combo "lit up" my face and 7 days later my face and scalp were virtually back to normal. Minimal pain, like a sunburn, and no scabbing, pus, etc. I was really scared to do the longer treatment after reading blogs and looking at pictures, but the new treatment is a piece of cake. Plus, according to related articles, it actually works better. A real win-win! "SCOTTSDALE, ARIZ. – A four-day topical combination regimen of 5-fluorouracil (5-FU) and calcipotriene removed almost 90% of facial actinic keratoses – significantly more than with 5-FU monotherapy, in a rando...

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Possible Dosages for this and Related Drugs:

Fluorouracil, 5-FU
  • Cream: 0.5%, 0.50%, 1%, 4%, 5%
  • Cream, Augmented: 4%
  • Injection: 50mg/ml
  • Solution: 1%, 2%, 5%
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Efudex: (1 result)

Sorted by National Drug Code
  • 0187-3204 Efudex 2 g/40g Topical Cream by Valeant Pharmaceuticals International

Other drugs which contain Fluorouracil, 5-FU or a similar ingredient: (5 results)

Related Efudex Topics:

Efudex-40 (fluorouracil)
Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this c... 22 replies
Efudex with Dovonex
Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50... 9 replies
Efudex 5%
Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swe... 8 replies
Efudex treatment effects
I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What shou... 4 replies
Efudex on scalp - side effects on hair?
Has anyone used Efudex on their head? I'm interested in any side effects on hair deterioration or loss. ## Hello Hoo... 3 replies
efudex40 application instructions
how and when should I apply efudex to my face? ## This is a drug used to treat certain types of cancer. How often and ho... 3 replies
Efudex-40
How to use and side efects ## please give me detailed description of how to apply and how long to apply efudex-40 ## I w... 3 replies
Efudex doesn't have to be a nightmare
I was prescribed Efudix to treat spots on the back of my hands. I have been applying a thin layer daily for 4 weeks. I h... 2 replies
Efudex (Fluorouracil) Cream 5%
I used this prescription on my forehead twice a day for 10 days. Removed all my ak's. Has now been about 1 year and ... 2 replies
Efudex, Dovonex and Desonide
My husband has been prescribed Efudex for 10 days (morning and evening on his scalp). Also, Dovonex twice daily and pop-...




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