Efudex

Active Ingredient(s): Fluorouracil, 5-FU
FDA Approved: * July 29, 1970
Pharm Company: * VALEANT PHARM INTL
Category: Cancer

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".



Efudex Overview

Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer.[2] By injection into a vein it is used for colon cancer, esophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer.[2] As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts.[3][4] When used by injection most people develop side effects.[2] Common side...

Read more Efudex Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source: en.wikipedia.org/wiki/Fluorouracil

Recent Efudex Forums: RSS Feed

Efudex 5%

Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swelling or any sign of side effects. Does this mean the spot on my lip is non-cancerous? I was under the impression I was to have swelling and pain, and that this cream kills everything allowing the good cells to regrow. ## have to start the efudex 5% cream once a day on upper and lower lips. I am extremely worried about the pain. Is there anything besides aquafor or Vaseline to he help with pain? ## It contains the active ingredient fluorouracil, which is used to treat areas of skin that have been heavily exposed to the sun, or those that have been tested to have Basal Cell Carcinoma. The FDA lists its typical side effects as possibly including skin redness, irritation,...

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Efudex treatment effects

I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What should i do? ## Hello, Judy! How are you? Have you informed your doctor, yet? The U.S. FDA does list the dryness/crusting as being possible side effects of using it. It may also cause abdominal pain, headache and mouth sores. How long has your doctor instructed you to use it? ## Medline Plus states "If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil. If you are using fluorouracil to treat basal cell carcinoma, you should continue using it until the...

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Efudex with Dovonex

Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50% Dovonex (vitamin D) and it was very fast and easy. Four days of application of the combo "lit up" my face and 7 days later my face and scalp were virtually back to normal. Minimal pain, like a sunburn, and no scabbing, pus, etc. I was really scared to do the longer treatment after reading blogs and looking at pictures, but the new treatment is a piece of cake. Plus, according to related articles, it actually works better. A real win-win! "SCOTTSDALE, ARIZ. – A four-day topical combination regimen of 5-fluorouracil (5-FU) and calcipotriene removed almost 90% of facial actinic keratoses – significantly more than with 5-FU monotherapy, in a rando...

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The 3-week Efudex / Fluorouracil nightmare is now unnecessary!!

Harvard Medical recently discovered a new treatment regime for AK. This new four-day Harvard Medical protocol is going to save us all from the Efudex & Fluorouracil nightmare: Adding calcipotriene to 5-FU dramatically reduced AKs I used this 4-day treatment for AK in Dec '18 and it works!! Save yourself from the 3 week fluorouracil nightmare and do this 4-day treatment instead. I made this Youtube video of my experience with this protocol: The treatment resolves actinic keratosis in only 4 days. No longer is the pain and discomfort of the commonly prescribed 3 week Flouracil necessary to clear your skin of these pre-cancerous lesions. Mix 5% Fluoroucil and Calcipotriene 50/50 and apply twice per day for four days. Both of these creams can be purchased through prescription. Your ...

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Fluorouracil stages?

Can anyone explain the stages and what to look for. I’ve been on Fluorouracil for 23 days suppose to do 4 weeks all over complete face . But face is peeling in some areas and turned a yellowiish crusty in some places. Also cracking and bleeding in tiny spots. Should I keep using it or is this the erosion phase. What to expect next?

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Redness after Efudex treatment

I have used Efudex twice over several years. I wonder what will help the redness that happens after the crust has peeled away? The affected area is upper lip and side of nose. ## Hi Ren, have you finished taking the course of Efudex at this point? Medline Plus says "If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil." It also says that the redness is normal, except in cases of a severe red skin rash (which should be reported as a serious side effect). Would you consider your case severe? As to treating the redness, you may be able to apply an over the counte...

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Sun and Efudex

I have quit treating my face and neck with Efudex and I am still peeling and having breakouts and the usual recovery. I am still treating my arms and hands. My work commute is 45 mins to 1.5 hours each way depending on the traffic with the average time in my car 2 hrs per day. When can I start getting that much sun exposure and it be safe? Always wear sunscreen too. ## Hello Daisy, According to the [1] NIH Efudex page warnings section it says that exposure to ultraviolet rays should be minimized during and immediately following treatment with Efudex because the intensity of the reaction may be increased. To me this sounds like you should avoid exposing the treated areas to the sun until it has completely finished recovering. The NIH goes on to explain that the redness and peeling typica...

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Shortness of breath using Efudex

After applying Efudex to the scalp after a shower I experienced shortness of breath at about 3.00am in the morning. This is not recommended - I should apply it mid to late afternoon. I have had no further effects since doing this. Has anyone else experienced this? My doctor said I may be allergic to Efudex. I hope not. ## Hello Ern, Your doctor is absolutely right, nowhere on the efudex website or the NIH/FDA warnings does it say that shortness of breath is a common effect of administering this medication. It sounds very much like you are allergic to this medication and I strongly suggest that you have your doctor run some tests to verify if you are safe to administer this medication. It would be tragic to have your throat completely close up because you were administering this medicati...

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Efudex-40 (fluorouracil)

Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this crazy? ## Not really. It is listed in the drug monograph that it can be used topically to treat certain cancerous or possibly cancerous conditions. ## Has anyone used it on their lips? Won't it just keep bleeding non-stop? ## Heidi- I've used it on my lips three times. Each time it was an application morning and at bedtime. Though about the second week it gets very sensitive and blister-like lesions appear that means it's working. I applied a product called Acquafor (like Vaseline Jelly) to seal it and protect). The healing takes some time but the outcome is worth it. ## I just used Efudex for 2 weeks on lower lip. from day 7 blistered and ulcerated and wept...

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Efudex on scalp - side effects on hair?

Has anyone used Efudex on their head? I'm interested in any side effects on hair deterioration or loss. ## Hello Hoody, Reportedly this will be determined by the amount of efudex that you need to apply. If applied topically then the medicine will not be absorbed into the bloodstream and thus will not cause hair loss like other forms of chemotherapy treatment. If it is necessary to apply enough cream that it will absorb into the blood stream then you will start to experience typical symptoms associated with chemotherapy such as nasuea, vomiting, hair loss etc. Below is a link to the source of my information. [1] Efudex Treatment I hope this answers your question. Let me know if you would like to know anything else regarding this medication. ## Thanks so much Kevin. Will be a 14 light...

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Possible Dosages for this and Related Drugs:

Fluorouracil, 5-FU
  • Cream: 0.5%, 0.50%, 1%, 4%, 5%
  • Cream, Augmented: 4%
  • Injection: 50mg/ml
  • Solution: 1%, 2%, 5%
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Efudex: (1 result)

Sorted by National Drug Code
  • 0187-3204 Efudex 2 g/40g Topical Cream by Valeant Pharmaceuticals International

Other drugs which contain Fluorouracil, 5-FU or a similar ingredient: (5 results)

Related Efudex Topics:

Efudex-40 (fluorouracil)
Need all information about this medication please. ## I have been told to apply Efudex to my lower lip, isn't this c... 21 replies
Efudex with Dovonex
Just letting everyone know that I just did the newest Efudex treatment protocol which requires mixing 50% Efudex with 50... 9 replies
Efudex 5%
Creme ## I have been taking applying 5% Efudex cream for two days to my lip per my Dr. Orders. So far, I have had no swe... 4 replies
Efudex treatment effects
I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What shou... 3 replies
Efudex on scalp - side effects on hair?
Has anyone used Efudex on their head? I'm interested in any side effects on hair deterioration or loss. ## Hello Hoo... 3 replies
efudex40 application instructions
how and when should I apply efudex to my face? ## This is a drug used to treat certain types of cancer. How often and ho... 3 replies
Efudex-40
How to use and side efects ## please give me detailed description of how to apply and how long to apply efudex-40 ## I w... 3 replies
Efudex 5%,cream,Fluorouracil
I used this prescription on my forehead.Twice a day for 10,days.Removed all my ak's. Has now been about 1,year.And a...
Sun and Efudex
I have quit treating my face and neck with Efudex and I am still peeling and having breakouts and the usual recovery. I ... 1 reply
The 3-week Efudex / Fluorouracil nightmare is now unnecessary!!
Harvard Medical recently discovered a new treatment regime for AK. This new four-day Harvard Medical protocol is going t...






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