Cortone

Active Ingredient(s): Cortisone
FDA Approved: * June 13, 1950
Pharm Company: * MERCK
Category: Anti-Inflammatory

Cortisone is a pregnane (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug; it is not synthesized in the adrenal glands. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys. Cortisone is converted back to the active steroid cortisol by the action of the enzyme 11β-Hydroxysteroid dehydrogenase type 1,... [wikipedia]

* May have multiple approval dates, manufacturers, or labelers.

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