Active Ingredient(s): Vortioxetine
FDA Approved: * September 30, 2013
Pharm Company: * TAKEDA PHARMS USA
Category: Antidepressant

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Brintellix Overview

Vortioxetine[note 1] is an antidepressant medication that is prescribed to treat depression. It relieves depression symptoms by increasing serotonin concentrations in the brain, by inhibiting its reuptake in the synapse and by modulating (activating certain receptors while blocking, or antagonizing, others) certain serotonin receptors. This puts it in the class of atypical antidepressants known as serotonin modulators and stimulators. It is made by the pharmaceutical companies Lundbeck and Ta...

Read more Brintellix Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

Recent Brintellix Forums: RSS Feed

Trintellix Review

Why did I read that you should not take this medicine till 2020? I was just given a lot of samples of 5mg that my doctor wants me to start for my depression. I am scared to death to start because of the horrible reviews & side effects that sound horrible. I have never heard of this drug. Can you please help me with this. Also if I do decide to start when is the very best time to take it? ## Has anyone else gone down from 10 to 5 mg of trintellix? I am afraid I will have some anxiety doing this. Can anyone give me advice? ## I've been on Brintellix/ Trintellix for going on 2 years. Saved my life. I am on a low dose, with buspar piggy back, but no longer a handful of drugs. If you've failed the rest, give it a shot. Start low. I am great on just 10mg, and I was suffering from ...

Scared to start Trintellix

I'm scared to start Trintellix. I have Major Depression. I get scared to start any new medicines but especially depression meds. My Dr gave me samples. I was also waiting to see if my insurance would cover it. (New insurance Oct. 1st) They said no unless I can produce dates and why others wouldn't work. That's impossible. I take Vyvanse and Klonopin. I've taken myself off depression medicines if they make me feel bad or weird. I can't take any that will make me gain weight. That just adds to the depression. After back surgery I only have 10 more lbs to lose. I can't do anything that I used to do because of back problems, so inactivity and not doing the things I love has made my depression worse. Other issues as well. I feel empty, things that used to make me shin...

Brintellix (Trintellix) withdrawal

Started 10 mg Trintellix 3 weeks ago. Vomiting at least 2x a day and constant nausea, fatigue, muscle and back pain. Trying to wean off it - doctor said take it every second day for a week then go see her. What is the normal time frame for withdrawal? I am terrified of this drug. I am diabetic and it is making my sugars wildly fluctuate too. ## Called Lundbeck (canadian office in Montreal) today to get advice on how to wean off/stop taking Trintellix. Shocked to be told "there is NO protocol for weaning/stopping this drug. You have to let your doctor decide how to proceed"! "Everyone has a different reaction". My doctor is away for a week so. My pharmacist and I are trying to figure something out, but I am absolutely stunned at Lundbeck's answer ## Hi Judy, Sorry to ...

brintellix side effects severe

DESPERATELY NEED HELP ABOUT BRINTELLIX!!! I have been on 5mg Brintellix for last 10 weeks. About 9 days About 9 days ago I started to feel like i was coming down with flu. week progressed and flu like symptoms got worse every day: flushing, feeling like i had high fever but without actual fever, agitation, muscle cramps, bad nausea, diahrrea all day long, fast heart beat, headache, etc. after several days of symptoms getting worse, on Sunday last I had the feeling i was going to DIE!!! worst flu like symptoms and severe anxiety, depression and suicidal thoughts. I skipped the sunday dose and then cut the monday dose down to 2.5mg. it is wednesday, and most of bad symptoms have gone to mild or moderate. Dr thinks i had case of serotonin syndrome n this med. But, no one can explain why si...

Have been taking brintellix for 3 months

Hello, I have been going to physiatrist and getting brintellix for about 3 months. Before taking any meds I constantly having suicidal thoughts very frequently. Then I start to go to physiatrist and taking brintellix 5mg for about 2 months, I was getting better until they change brintellix dose to 10mg. Now I’m back to where I was before taking any meds, getting worse and worse. Do anyone know how to help and why? ## I found the same when I went from 5mg to 10mg it kinda made intrusive thoughts amplify I have found after about 8 weeks that 5mg is best taken at night that way I dont get the nausea and just feel relaxed even 2.5mg would be ok for me I think.. ## The NIH does warn that these issues can be a side effect of this medication, and it is normal for them to worsen, when you...


I was on Trintillex for about 3 weeks and developed a rash all over my body. I didn't know where it was from originally so I did not stop taking it. After about 21 days I decided to stop taking it because my doctor said it could be a potential side effect. My rash is so severe and I have been off of the medication for about a week now but the rash won't subside. Does anyone have an idea of when it will go away? I know the half life is 66 hours so I am nervous it's going to be in my system for a long time and the side effects won't go away. I was taking 5 mg. If anyone has any ideas of when it will go away or how to help it/ make it go out of my system faster PLEASE let me know. Thanks ## Julia! I am so sorry about the problem you've experienced. How are you doing, no...

Stopped Brintellix

I was on 10 mg of Brintellix for about 4 months and then my doctor added 10 mg of Rexulti. I felt like i was being stimulated. He then upped my Brintellix to 20 mg and my anxiety went crazy. I was having racing thoughts and couldn't sit still. In my mind i had to be doing something all the time. I also started having panic attacks. This was only over a 2 week period. I then dropped back to 10 mg and cut my rexulti to 5 mg. I told the doctor I wanted to switch back to celexa. He told me to just stop the Brintellix and start the celexa at 10 mg. It's been about 2 weeks now and I still have panic attacks and I wake every morning feeling anxious which last most of the day until the evening. I can't handle this anxiety. I feel amped up. It's like the side effects are continui...

best time of day to take brintellix

I can't seem to figure out what is the best time to take my trintellix... am or pm. I've been on trintellix for a little over a month and don't sleep very well and stay very tired during the day but I had these problems before I began trintellix so how am I supposed to figure out the best time of day to take it??? I've been taking it at night but switched to taking it in the morning today amd can't tell any change. I just want to take it at the time of day it will help me the most.... Thanks! ## There is really no specific time that is best, it depends on what works for you, the main issue is to just be consistent in taking it regularly. The FDA warns that it may cause side effects, such as nausea, dizziness, headache, mood changes, and weight changes. How long have ...

Switching from Zoloft to Brintellix

Today my doc told me to reduce my Zoloft from 100 MG to 50 MG for the next 6 days. On the 7th day I will begin 10 MG of Brintellix in the morning with breakfast. If I experience any sleepiness I should start taking it in the evening. My follow up visit is scheduled for June 29. I have tried many amtidepressants over the years with minimal to moderate success. I hope this is magic bullet. ## don't do it! i have been on ssri meds for over 20 yrs. dr started me on trintellix 3 wks ago. have not been out of the house since then due to nausea, vomiting, diarrhea, fatigue and more. Now trying to wean off of it but dr and pharmacist are not sure how to proceed with this. i am also imsulin dependent diabetic andy sugars are erratic. terrifying drug at least for me. ## Day 6. I have complete...

Brintellix/Trintellix Long term side effects

I have struggled with depression for most of my life, and am always in search of the perfect antidepressant. I work with a psych doctor who is always willing to try new things. 10 months ago I started 5 mg of Brintellix daily, within a week my mood was significantly elevated, I was sleeping better, waking up much earlier and was more motivated to do things in the morning. I went up to 10mg daily However the nausea was dreadful! I pushed through for a couple of weeks, changed to taking the brintellix at night and after a while it subsided. My mood got better and better, I had recently turned 50, and had gained a little weight, so with my new found morning energy I started working out 2times a week with a trainer, and then walking most other mornings! The walking then changed gradually to...


Possible Dosages for this and Related Drugs:

  • Tablet: 10mg, 15mg, 20mg, 5mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

NDC Database Records for Brintellix: (5 results)

Sorted by National Drug Code
  • 64764-550 Brintellix 5 mg Oral Tablet by Takeda Pharmaceuticals America, Inc.
  • 64764-560 Brintellix 10 mg Oral Tablet by Takeda Pharmaceuticals America, Inc.
  • 64764-570 Brintellix 15 mg Oral Tablet by Takeda Pharmaceuticals America, Inc.
  • 64764-580 Brintellix 20 mg Oral Tablet by Takeda Pharmaceuticals America, Inc.
  • 69189-0560 Brintellix 10 mg Oral Tablet, Film Coated by Avera Mckennan Hospital

Other drugs which contain Vortioxetine or a similar ingredient: (1 result)

Related Brintellix Topics:

brintellix side effects severe
DESPERATELY NEED HELP ABOUT BRINTELLIX!!! I have been on 5mg Brintellix for last 10 weeks. About 9 days About 9 days ago... 65 replies
Brintellix/Trintellix Long term side effects
I have struggled with depression for most of my life, and am always in search of the perfect antidepressant. I work with... 30 replies
Brintellix (Trintellix) withdrawal
Started 10 mg Trintellix 3 weeks ago. Vomiting at least 2x a day and constant nausea, fatigue, muscle and back pain. Try... 21 replies
brintellix nausea & headache
I've been on 5mgs for 2 weeks now. Having nearly unbearable side effects so no increase yet. Was supposed to up to m... 10 replies
brintellix and zoloft
Hi. I'm about to switch over to Brintellix from Zoloft. The Zoloft has been good for my depression, but my libido is... 5 replies
brintellix...high blood pressure
I was prescribed this for anxiety and it is working very well for me. I have been through several drugs and for the firs... 5 replies
Brintellix nauseated vomit vomiting
Hi, I was hoping that I may find some people to with similar symptoms after taking Brintellix. 25th of June I began Brin... 5 replies
Brintellix 10mg
I have been on brintellix 10mg for a little over a week and I feel worse. Flu symptoms, vomiting, very weak, tired but c... 4 replies
brintellix start up and dose increase
Hello, I started Brintellix 4 weeks ago. I started with 5mg and tapered off Effexor over the next 2 weeks (bad reaction ... 4 replies
Brintellix and Migraines
My wife has been on Brintellix/Trintellix for nearly a year now with great results. No other anti-depressant has been as... 4 replies

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