Category: Antiprotozoal / Anthelmintic

Bithionol Overview

Bithionol is an antibacterial, anthelmintic, and algaecide. It is used to treat Anoplocephala perfoliata (tapeworms) in horses[1] and Fasciola hepatica (liver flukes). Mechanism of action Bithionol has been shown to be a potent inhibitor of soluble adenylyl cyclase,[2] an intracellular enzyme important in the catalysis of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP). Soluble adenylyl cyclase is uniquely activated by bicarbonate. T...

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