Active Ingredient(s): Isotretinoin
FDA Approved: * May 7, 1982
Pharm Company: * HLR
Category: Skin Care

* This drug may consist of multiple approval dates, manufacturers, or distributors. If applicable, they would be listed below under "NDC Database Records".

Accutane Overview

Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication primarily used to treat severe acne. It is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer, tre...

Read more Accutane Details
Details May Include Instructions, Side Effects, Interactions, Etc. Drug monograph is from Wikipedia. All text is available under the terms of the GFDL (GNU Free Documentation License). Source:

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Accutane serious side effects for our son

Our son started taking Accutane the end of Dec, 2011. He was on it for 6 weeks. He ended up in Feb. in ER with a foot long blood clot in his groin down his leg. He had other symptoms prior to this as well. He had your normal side effects which we expected, like dry cracked lips, flushed face, more acne in first month, head itched. Then he had back pain, joint pain, (basketball player in his High school so was very active) Then he would at times feel faint when standing. He started getting really sick when his blood clot started hurting him. We didn't know what it was and went to the doc 2x for pain. This is listed as a rare serious side effect. Please be careful while taking accutane. We won't be touching it again at our house. ## I am very sorry about what happened to your son,...

Accutane and erectile dysfunction

I was on Accutane for 27 days. I had to stop because of muscle weakness and erectile dysfunction. It has been a month now since I stopped taking it but seems like the erectile dysfunction and muscle weakness are not going away. I would like to ask is there anyone who has experienced the same symptoms and recovered later? ## Accutane has been known to lower testosterone levels in some people that take it, and it been suggested that this should be added to the expected side effects list. Ref: Isotretinoin Risk of Coital Side Effects That said, after a month, three would usually be some improvement. What has your doctor advised? Are you on any other medications?

Can Accutane affect my growth plates?

I went to the dermatologist for my acne and they prescribed me accutane. I took it for 3 days. But then on my third day I found out that it could stunt my growth. This really freaked me out since my dad and uncles got their growth spurts at 17, so I told my mom and she said I can stop taking it. I had my last week of PE 12 after stopping. I’m aware that three days is fraction of the full course (6 months), but is that enough of the chemical & time to have a negative on my growth plates? ## Yes, it has been known to cause premature epiphyseal fusion, (fusion of the growth plates), and precocious, or early, puberty has been known to occur in some people that have taken Accutane. In this case, puberty refers to your final growth phase for height. Ref: Medline Plus Accutane Here...

Accutane and seizures

I took roaccutane in 1996 and again in 1997. Each time was for around 6 months. I had a 6 minute tonic clonic seizure in August 2011 and another one in January 2012. I'm wondering whether this is related, although it is a big gap. Has anyone else developed seizures 15 years or so after finishing roaccutane? ## YES....I Hate to Even Admit it..But..I have had several Seizures....Some lasting 15 minutes...It is Like being trapped inside a body that will not work..or even perform the simplest tasks....I could see...and realize..I was drueling...but my right arm was contorted..and my left arm was basically rigid....I believe it is About time..We all find a way to form a network...of people...that can compare notes.....More aptly...than on here..Please contact Me. ## I can't say wheth...

Accutane and Infertility

I took accutane almost 14 years ago as a teenager. I am now a 32 year old woman who has just been diagnosed with infertility that they believe is linked to autoimmune issues. I truly believe that accutane is the cause of this; from the research that I have done it seems that accutane has been linked to other thyroid-related diseases, but that they have not yet been able to prove a link between accutane and infertility. There are, however, actually more people like me out there than I originally thought. Being diagnosed with ovarian dysfunction has been a horrific, horrific blow. And while there was plenty of information about accutane and birth defects, no one ever mentioned a possibility of future infertility. I was a teenager! This is a tragedy and I believe something should be done a...

Isotretinoin and throbbing sensation on face

Hi there! I am on my second week of low-dose isotretinoin. My skin flushed mostly around my nose and I can feel my pulse in the areas. Is this normal and does anyone have any idea why this happens? Thanks ## Yes, it has been known to cause these types of sensations as side effects, according to FDA reports, along with skin scaling, peeling, easy bruising, and sweating. Ref: Medline Plus Isotretinoin It's kind of hard to say why any particular side effect happens, it just has to do with the affect that a medication has on the body when working to do its job. Are you on any other medications? Have the side effects improved, at all?

Accutane long term side effects

I have a son that took accutane 60 mg a day for six months in a row three years ago. Now after many trips to doctors over strange medical problems, it seems accuatne is the culprit medication that has caused servere joint and muscle pain, severe dry lips, redness in face, eye infections of own immune system attacking itself, systems of osteoarthritis in both shoulders, both wrist and right hand, blood in stool, possible hair loss, abnormal liver function test results in AST and ALT. My son went from being a high school football and track athlete while taking this medication three years ago to someone that is in constant pain just washing a car. After I have researched this drug extensively, I can't believe that the FDA allows this drug originally made for cancer patients to be marke...

Tattoo before Accutane?

I want to get a very small tattoo on the back of my neck. I'm supposed to be starting my Accutane on Friday. I know you're not supposed to get tattoos whilst taking Accutane because it can affect the healing process but if I get the tattoo and start my Accutane a week later when the tattoo has healed, do you think this would be a problem? ## It would be best to double check with your doctor, as it may require a longer time period, or might not be advisable, at all. Accutane has been known to cause side effects, such as nausea, dizziness, elevated levels of fats in the blood, and birth defects if a woman becomes pregnant while taking it. Are you on any other medications?

60 and Accutane

I am a 60 year old male who has had acne for 40 years. Eventually, after many years, my doctor sent me to a dermatologist. She prescribed 60mg a day and, after 6 weeks, I feel like a zombie! Aches, pains - I feel my age. Anyone else out there who takes this at my age? ## I would stop Accutane! You do understand that Accutane is a Chemo drug....If you delt with Acne for 40yrs then I would suggest you find others ways that are safer. There are teens and young people like me who now have joints and bones of that of a 60yr old due to this poison. What have you tried in the last 40yrs for your acne? ## I am a 52 year old women who has been on accutane for 1 month. I had severe acne and severe oily skin since I was 13 years old. I am thrilled so far with the results with accutane. I am having...

autoimmune disorders linked to accutane?

I took accutane in the early 90's when I was in my 20's. I took all but the last "phase" of the prescription. I had no problems with it at the time. The only warning from my dermatologist was don't get pregnant. In 2009 I developed a blood disorder and autoimmune disorder. I have pain in my joints and fatigue. My husband is convinced that it is from accutane. I have had many stays in the hospital because of this. Has anyone else developed these or similar symptoms? ## Hi, yes, I have been diagnosed with multifocal motor neuropathy recently, which is believed to be autoimmune and currently has no cure. I dont know how to stop the damage. My diagnosis means the disease is progressive, and will cause severe disability. ## Sorry to hear about both your experiences coming...


Possible Dosages for this and Related Drugs:

  • Capsule: 10mg, 16mg, 20mg, 24mg, 25mg, 28mg, 30mg, 32mg, 35mg, 40mg, 8mg
Note: Above list includes dosages for all drugs with the same combination of active ingredients.

Other drugs which contain Isotretinoin or a similar ingredient: (8 results)