Why Take Methylprednisolone Before Breakfast?

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You're supposed to take the first two tablets of Methylprednisolone before breakfast. My question is how long do I have to wait to eat breakfast after I take the medicine?

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1

Hello, Maria!

Actually, it is usually taken with breakfast, as you are eating, otherwise, the FDA warns that it can cause a lot of nausea, stomach irritation, and dizziness as side effects.

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Top Answer
You probably don't need to wait long to eat breakfast after taking your first dose. Maybe 15-30 minutes tops if you're concerned about absorption (as the medication has a peak concentration about 2 hours after ingesting it). Actually, according to Medline Plus, Methylprednisolone may cause an upset stomach and you should take it with food or milk.

Why take it before breakfast?


Taking medication at the same time every day, such as before breakfast, can establish a routine, making it easier to remember and ensuring consistent dosing. Also, Cortisol, a naturally occurring steroid hormone produced by the adrenal glands, has a circadian rhythm in the body. Its levels peak in the early morning shortly after waking and decline throughout the day. Taking methylprednisolone in the morning helps to mimic this natural pattern, potentially leading to fewer side effects and better symptom control.

The dosage timing listed on the product label of Methylprednisolone 4mg dose-packs provide the following recommendations:
  • Before Breakfast
  • After Lunch
  • After Dinner
  • At Bedtime
If in doubt, the best advice is to simply follow your doctor's instructions carefully. Your doctor in conjunction with your pharmacist should inform you on how much medication to take, how long you should take it for and when you should plan on taking it each day.

Additional tips for taking Methylprednisolone:

  • Take the medication at the same time each day.
  • Take the medication with a full glass of water.
  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and go back to your regular schedule
  • Do not take more than the prescribed dose
  • If you experience any side effects while taking Methylprednisolone, be sure to tell your doctor.
  • Avoid grapefruit juice while taking Methylprednisolone, as grapefruit juice may increase blood levels of Methylprednisolone.
Hope this helps! This is not medical advice and you should consult always with your doctor.
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3

Do you take methylprednisolone while you eat or before meals? What does this medication help with?

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4

Why in the world does it state to take 2 doses of Methylprednisolone before bed if it can also make you nervous & hyper? I've taken it before. It works for the pain. However, it makes me crazy like I just want to jump out of my body!!! I'm going to start a new Rx in the morning. The Medrol packet.

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Re: Verwon (# 1) Expand Referenced Message

I forgot to take it before I ate breakfast. Is it ok to go ahead and take it?

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Re: Verwon (# 1) Expand Referenced Message

Can I take it if I already ate?

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Re: Verwon (# 1) Expand Referenced Message

What about with chlorthalidone?

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8

I just got home from the drugstore at 9:45pm and was trying to figure out whether to start methylprednisolone and take 2 before bed or wait to start in the am? Thanks.

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Re: brenda (# 8) Expand Referenced Message

Unless you're dealing with something really acute, you might want to wait until your first dose in the morning. That's because insomnia and stomach upset are possible side effects.

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