Which Is Stronger Hydrocodone/acetaminophen 5-500 Or 10-325.

3 Replies Updated January 26, 2017

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Louise Says:
Wed, Sep 11 '13, 1:28 PM

I have 2 different prescriptions for after knee surgery. Which is stronger for pain?

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Verwon Says:
Thu, Sep 12 '13, 11:46 AM

Hi, Louise! How are you feeling?

Since the Acetaminophen augments the action of the Hydrocodone in these, they are both likely to be about the same, actually.

Learn more Vicodin details here.

One may work a bit better for you than the other, but there's no way to know that, unless you try them.

How did you end up with 2 different prescriptions?

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Kat Says:
Mon, Aug 18 '14, 8:21 AM via mobile

Actually those 10/325 will be stronger. The 10 is the Vicodin and the 325 is the acetaminophen. I broke my arm 3 yrs ago and was already on 5/500 they gave me 10/325 and they were MUCH stronger to me than my normal 5/500.

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MIMI6 Says:
Thu, Jan 26 '17, 8:13 PM

!0/325 10 is the hydrocodone. You could go to the grocery store for the tylenol that constitutes the 325

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