Wellbutrin / Oxycontin / Oxycodone

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Alex Says:
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I am suppose to take 150 mg of Wellbutrin twice a day. I was also prescribed OxyContin 10 mg every 4-6 hours, along with OxyCodone 10mg every 4-6 hours (as needed).
So, here is my problem. (Y, the Doctors do know that I am on all 3 of these meds together). I don't know how long I need to wait after taking a Wellbutrin before I can take an Oxy w/o running the risk of Seratonin Syndrome(?). Oxy doesn't make me loopy at all. It hypes me up like Adderall, and that's before I add a Wellbutrin.
Can anyone help or advise. My Doctors just say a couple of hours. But, so far, 2 hours isn't working. I need something more precise.
How soon can you take an OxyContin after taking an Anti-Depressant???

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Verwon Says:
Hello, Alex! How are you?

I'm not finding anything about a risk of serotonin syndrome between these, what I find listed is that the Wellbutrin can actually increase the efficacy of the Oxycodone to make it more potent. There may also be a slight risk of experiencing seizures.

Where did you find that there was a risk of serotonin syndrome?

This is a narcotic analgesic, so it has the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation.

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Alex Says:
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That is my problem. I don't know how long I should wait.
I take my Oxy at 6:30 am
How soon can I take my Wellbutrin so that I DO NOT get the Seratonin Syndrome effect??
What about when I take my Wellbutrin? How long until I can take an OxyContin or an OxyCodone??
Thanks again for any and ALL assistance!

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Alex Says:
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Thank you so much!!! I don't know why I didn't research that before! This info really helped me! I can't thank you enough!! Now, maybe I can get on with life! I was on Morphine before and found out about Seratonin Syndrome the hard way. I just assumed that all pain killers and anti-depressants did the same thing.

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Nurse Says:
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Hi Alex.

Please be careful mixing the three medications together. You need to contact your doctor or pharmacist and ask these questions about how soon you should take them either together or apart. Just concerned. Good luck. Nurse.

You can also call call Poison Control and ask them as well. They will be glad to help you.
They will not judge you Alex.
They have a special number just for this type of situation. Sincerely Nurse.

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