Timing Of Linzess & Food

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Has anyone played around with the amount of time they leave between taking linzess and eating? if i eat an hour after taking it rather than 30 minutes, will i experience more or less diarrhea?

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1

Hi Sarah,

According to the manufacturer, it is recommended that Linzess be taken on an empty stomach, "at least" 30 minutes before your 1st meal of the day. Apparently taking Linzess on an empty stomach allows it to work more efficiently; whereas taking it closer to meal-time may result in it not being quite as effective. So the notion of taking it an hour before a meal shouldn't be a problem - at least in my opinion. Also, since diarrhea is listed as a general side effect of Linzess, I think the possibility of it occurring may be independent of whether or not you take it too close to meal time. Side effects are just unpredictable in that way. You never know when they might occur. On the other hand, it would probably still be a good idea to play around with the timing of your dose in order to see how your body responds, since there's really no other way to know for certain how you will react ahead of time. As with any medication, it can be a game of trial and error to find what works and what doesn't.

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2

By me it works only when I take it WITH food.
I've been taking it for about a month now.
The best way it works for me is to take it at night with food before I go to sleep. Morning didn't work for me, night on an empty stomac didn't work for me. Only night with food, in the morning I'm in the bathroom.

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3

I have been on Linzess for one month. Take it in the morning 30 minutes before a meal. Sometimes it works and other times constipation.. If I take it with food sometimes it works and other times I have to run to the bathroom. What do you think about taking it an hour after I eat in the morning?

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