Taking Subutex And Percocet Together
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Comments Submitted Says:
 
My doctor just put me on subutex along with percocet. I've been on percocet for yrs for severe and chronic migraines. He told me to take the subutex and if it doesn't work to take a percocet. I usually take 15 mg percocet at a time. I've read some stuff online that worries me. Some people say if you take percs with subutex you'll go into withdrawals. I went through severe withdrawals with fioricet months ago and I don't want to go through that hell again. I took my first subutex about an hour ago and I still have a migraine so I want to take a perc now. Can I do that or will I get sick?

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576
Hi Says:
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Mr clean (# 575) --

I will settle it for you. I posted below as I work as a nurse in a pain clinic at Brigham and Women's hospital in Boston. We have a patient on 6mg of subutex but she takes it 3 times a day for pain. Today she came in as sick as a dog; sweat dripping off her face, twitching and shaking. We asked her what happened she said she took her 6am 2mg dose of subutex and was fine. But at 10am she had horrific pain (she has a bad nerve disorder) so she tried taking a 2 perks at 10am for the pain. (It was from an old script before she switched to subs) she said the perks did very little but she was desperate. She knew it was wrong to take but she planned on telling the doctor because apparently she's been having a very bad week. Anyway, she then continued and took her next dose of subs at noon and she said by 12:20 she was drenched in sweat and started shaking. She didn't think she would make the appointment at 1. She was so sick. The doctor told her she never should have taken the subutex so soon after the perk. He was also angry since she was no longer prescribed it. He told her not to do it again or she would get in trouble. But he did tell her that when she took the perk at 9am or whatnot, then she should have waited at least 12 hours before taking her next dose of subutex. So yes you can take them but you have to wait 12 hours after taking an opiate to start taking the subs again or you will be very sick like this patient today.

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575
Mr clean Says:
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kkh (# 569) --

Like I said... So many people posting incorrect information but are to stubborn to beleave anything different. Go ahead and take subutex after percs. Then please settle this by letting everyone know you didnt go into WDs or nothing elce dramatic happend.
.
.

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574
Ken Says:
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Your doctor is wrong...it is absolutely absurd to be on both medication. Subutex will fill your opioids receptors and there will be no where for the Percocet to attach itself. What I don't understand is why are you taking subutex if your going to continue to use opioids.

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573
Mr clean Says:
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Strongarm (# 546) --

You are absolutely correct. Im reading a lot of posts were people are very confused and to stubborn to admit they are wrong.

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572
Ken Says:
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I've been on Subutex for almost 10 years at 16 mg. I had surgery and came off the Subutex a day before. The doctor only prescribed me perk fives and I've been on them for almost 5 days. The Percocet or not satisfying my withdrawals do I need to wait to take my Subutex

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571
Hi Says:
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My name is none of your business (# 552) --

You are so wrong!! Like the above posters said, it is the BUPE not the naloxone that causes precipitated withdrawals. I work at a pain clinic at Brigham and women's hospital and we get this question ALL THE TIME. Buprenorphine is very sticky to the receptors and if you take say Percocet after either suboxone or subutex you will be fine. The problem comes if you then try to take the subutex or suboxone AFTER taking the perks. Since bupe has such a high affinity for the receptors, if you take a perk and then take bupe after, it will kick ALL of the perks out of your receptors (because AGAIN the subs have a super strong affinity to go in the receptors) and you will be thrown into horrible withdrawal. Trust me I have seen it in patients that didn't listen and decided to take a pain pill and they were very unhappy campers. Precipitated withdrawals can last for a good amount of time (probably feels like forever). But people need to stop posting false information!! Subutex/suboxone are both made of bupe and that is the blocker. If you are on a low dose, say 2mg and you take a pain pill you will get some relief but not a ton. So please people just know that bupe is the problem when it comes to precipitated withdrawals. I have only seen one person be able to take subutex 4 hours after taking dilaudid and she did not experience the withdrawals. The reason, my clinic believes? Is because this person is a rapid metabolizer of opiates. The head doctor put her on methadone and after 2 weeks she started burning through it so fast that she would go into withdrawal 5 hours after her dose, and she took it 4 times a day. By the 3rd week she was in a constant state of withdrawal bc the methadone was being burned so fast. To confirm this "belief" the doctor did a special genetic evaluation on her to see if she was a rapid metabolizer and she was. But that is the only time we have seen someone not experience withdrawals. It's because she has an excess of an enzyme in her body that is responsible for metabolizing methadone.

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570
Fred Says:
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Nuna (# 556) --

Yes you are correct. You can take Percocet if needed for pain on top of suboxone or subutex. But it will only help the pain better. But I'm a recovering addict and I take my program serious. I'm on 60 suboxone and 30 subutex a month. 3 a day. Which is alot better cause I got my life back. Was taking 30 to 40 opiates a day. But I've had kidney stones and had to take a Percocet a couple Times

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569
kkh Says:
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Pinky33 (# 565) --

You are wrong when you say that Suboxone "has the blocker" and that Subutex does not. The Buprenorphine ITSELF is a "blocker". Bupe is a partial opioid AGONIST, partial ANTAGONIST. The ANTAGONIST part acts as what you are calling a "blocker". In fact, the Naloxone in Suboxone is only there to keep people from injecting it. When taken sublingually (under the tongue) Naloxone is only around 5% bioavailable. So when taken properly, it is really only the Bupe that is doing any "blocking". The Naloxone virtually does nothing unless it's injected. People who think you can use full agonist opioids side by side with Subutex, because they mistakenly think the Subs contain "no blocker" could be in for a rude awakening. Precipitated withdrawals are from HELL!!!

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568
Why Says:
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Hi~
To me that is strange your doctor put you on that combination. Because my son is on the same medicine minus the Percocet. She told him if you take Percocet or any other narcotic you will just pee it out. It will do nothing absolutely nothing. Good luck.

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567
Pinky33 Says:
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Just FYI... The primary difference between SuboxoneandSubutexis that one of these medications also contains a substance called “naloxone”, while the other one does not: Subutex contains a single active ingredient: buprenorphine.Suboxone contains two active ingredients: buprenorphine and naloxone. Because buprenorphine is the active ingredient inSubutex, the medication can achieve this effect. However, Subutexis not meant to be used like a naloxone inj. or anopiateblocker in most instances. It is, for the most part, used "for the treatment of opioid dependence" (FDA).

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566
Pinky33 Says:
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kkh (# 562) --

Percocet contains oxycodone. Just wanted to clarify that. It was miscommunicated.

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565
Pinky33 Says:
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Jackhammer (# 12) --

No blocker in subutex. Suboxone has the blocker. Not subutex. You can feel opiates still just not full effects and it may make you slightly sick. Headache & naseated

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564
Joe clean Says:
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Speaking of WDs. My doc had me on (started with percocet and working up over time) 80mg oxycontin, 6 per day for over 5 years. He took me off them cold turkey. He said i would have flu like symptoms for a couple days... What a D*** Head!!! Over the next year i lost my job, my home and my wife. About all i had left was my pickup... and it had bald tires and expired registration. That was a long time ago. Luckily a friend knew a friend that gave me a few subs and pointed me to a good inpatient rehab. And without the combination of the friend, the subs and the 28 days of rehab who knows how it would have ended. My point being that doctors are often clueless as to the road they are starting you down when they prescribe opiods. Why did the FDA approve such a dangerouse drug. I truly wish i was still living the life i lived before opioids.

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563
Katyaronnie Says:
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Thank you!!!! I'm going to have knee replacement surgery. I'm currently taking 2 suboxone a day! What u r saying is I have to switch over to subutex so I can take the pain meds!!!! I will have to talk to my sub Dr as well as my surgeon! You have been so helpful with the correct information which I appreciate greatly! (I was severely addicted to fiorinal#3 when I stopped taking it my migraines went away which is why I was on it! Amazing)

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562
kkh Says:
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DADA: You should be ok. With Percocet, I would say 12 hours minimum. Stronger opioids like Oxycodone, I would wait at LEAST 24 hours (unless the medication is really bad quality). I don't know how much Subutex you're on, but start slow. Take 2 milligrams, wait 30 minutes. If you are ok, take another 2mgs, wait... do that until you are back up to your normal dose.

When I went thru precipitated withdrawal, it didn't take long to know I was in trouble. I had 2 mgs under each side of my tongue... in about 15 minutes, I started feeling worse and worse and WORSE... Ugh. So just take it SLOW.

You can also look at the COWS scale;
https:/­/­www.mdcalc.com/­cows-score-opiate-withdrawal. Good luck.

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561
Dada Says:
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My last dose of Percocet was at 4 pm today. Can I restart my subutex in the morning with no withdrawals

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560
Aa1w Says:
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It's called opana. .....the oxymorphone most doctors don't prescribe it anymore it's super strong and addictive.

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559
kkh Says:
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DAVID: Not only is it amazing that people are dispensing this misinformation, but that they clearly have no clue about the things they are putting into their own bodies! But to come on a forum like this and give "advice" when they have it wrong... to people who are genuinely seeking information....you can only hope no one actually LISTENS to them!

Not to mention all these *****s who are seeking ways to abuse these ORTs, which are made to help people STOP abusing drugs...that pisses me off. Especially when there's only a limited number of Bupe doctors out there. Leave the ORTs to those of us who ACTUALLY want to be clean! PEACE

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558
David Says:
 
@kkh,

Thank you for continuously sharing the truth about buprenorphine! I know I've seen your posts in numerous related threads discussing this same thing and it never ceases to amaze me how many people are misinformed about this topic. Just wanted to let you know that your posts are always appreciated and don't go unnoticed! :)

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557
kkh Says:
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NUNA: Taking the Percocet AFTER being on Subutex won't throw you into withdrawal, but taking the Subs too soon AFTER the Percs will. And when you say "it's an opiate".. to what are you referring? Every drug you mentioned in your comment is an opioid, so ???

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