Stopping Xeljanz

5 Replies Updated

Conversation Starter

Susan Says:

I was on xeljanz for 4 months, unfortunately had to stop last week due to decreased platette count. Since then I became very depressed and increased anger, I could even say I have rage, which is very unlike me. Has anyone experienced this by stopping this drug? Please respond. I'm very concerned over this behavior.

Showing Replies 1 - 5 of 5 RSS Feed

Page of 1     Sorted By:
David Says:

Hi Susan,

Sorry to hear about your experience coming off of Xeljanz. It sounds like your best bet would probably be to sit down and talk with your doctor about ways to provide more relief from your symptoms; at least until they start to subside.

When it comes to symptoms of anger, depression, and irritability, I believe those are really just chemical imbalances trying to sort themselves out as your body continues to adjust to not having the medication. Knowing that, hopefully you can try to react to those feelings in a more understanding way that allows it to pass through you quicker and not effect you as much (emotionally) as it would normally.

In my opinion, there should be more warning labels letting patients know about the possibility of withdrawal symptoms when stopping so abruptly like that. However, there are also various types of treatment options out there to combat those adverse effects.

You can learn more about this drug on the page for Xeljanz Details

I hope this helps!

Was this helpful?     0     0  
cj Says:

I had to stop Xeljanz too because of increased anxiety and severe rage. I felt extremely angry and depressed. It just came out of nowhere after being on it for a little over 2 months. I stopped it and within a couple of days I was back to myself. No anger or increased anxiety. I've been on many Biologics. This was truly the scariest as far as side effects are concerned.

Was this helpful?     0     0  
Remi Says:
via mobile

My sister was on xeljanz for six months and had to stop because it brought her immune system so low she got shingles for the first time. After 2-3 weeks of stopping her RA pain started again and excessive vomiting. Now four weeks later the mood swings, anger was switched on and it is unlike her. These meds are really horrible and nothing is told about the withdrawal effects. This is irresponsible of MDs and drug companies because it would cause a patient to think she is depressed and spiral down another drug forming path by MDs who are so ready to prescribe.

Can anyone chime in on what has helped these withdrawals?

This is purposely done so patients are forced to go back into their habit forming drug.

Was this helpful?     0     0  
Remi Says:
via mobile


I am wondering if you could elaborate on what you found helped during the withdrawal from xeljanz The switch in emotions after xeljanz was stopped is also happening to my sis. Thank you.

Was this helpful?     0     0  
Di Says:
via mobile

I have been on xeljanz for two years successfully, love it. I want to have a shingles vaccination and as it is a live vax I will need to go off xeljanz to have it. I just wondered if anyone has done this and how long you had to stop taking it before and after the vax, as it is the only medication I am on now. I also wondered how long does it keep working for after ceasing use?

Was this helpful?     0     0  

Viewing page 1 of 1     Reply

More Discussions:

Stopping Lisinopril
I have been taking 10 mg/day of Lisinopril for 3 months and have developed a tightening in the chest and flu like sympto... 126 replies
Stopping Levothyroxine
I have been taking Levothyroxine .88mg for the past two years. I just left town on a three week vacation and realized I ... 126 replies
Stopping Xarelto
I have been instructed to stop my 20mg a day after being on it for 6 months (2 PE's one in each lung at Xmas) and I ... 118 replies
Stopping Eliquis SAFELY
I've been taking Eliquis for a couple months after a bout of a-fib. I'm back in sinus rhythm and am in the low r... 31 replies
Stopping Contrave
How do you stop Contrave when you are at your goal weight? Do you go down in dosage or stop cold turkey? ## Follow the t... 10 replies
Stopping Methadone
I'm on 75 mg methadone and I want to stop on my own because it seems my counselor wants me on forever. Can I do it m... 9 replies
stopping lexapro (concerns, advice?)
Hello All, I was prescribed the generic for lexapro at 10mg daily about a month ago. The first week I felt an increase i... 7 replies
stopping suboxone after taking only month
If I have only been taking 8 mg. of suboxone a day for one month, can I stop suddenly without withdrawals? ## No, it wil... 6 replies
stopping xarelto due to bleeding
A fall produced a cut and abrasion. Bled for 5 days so stopped xarelto 15 mg/day. Had taken for 4 months for DVT. Am now... 6 replies
Stopping Belviq!!
I stopped taking Belviq about 5 days ago. I have had a headache since. Before I stopped taking Belviq, I was feeling wor... 6 replies

Post a Reply

No registration needed.
Simply fill out the form below.



 Optional, stays hidden.
Get notified when a reply is posted here.

4) Text Verification: *
Prevents SPAM.

Click here to show the question

with the privacy policy (20191231).

This form will be submitted securely


Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use and Privacy Policy. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.

Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 13 August 2017.

We are committed to your privacy.

Copyright © 2005-2020 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA