Muscle/nerve Ache With Eliquis And Niacin Or Statin

199 Replies Updated

Conversation Starter

Larry Says:
Since starting Eliquis, I have felt much stiffer and sore in the mornings and during the day with muscle tightness in my neck and back affecting my upper arms. A general sense of early aging that is unpleasant. Anyone else with these symptoms?

Showing Replies 1 - 20 of 199 RSS Feed

Page of 10    Next Page     Sorted By:

David Says:
Hi Larry,

Based on my research, the following symptoms are listed as serious side effects of Eliquis (apixaban) that should be reported to your doctor immediately:

-numbness, tingling, or muscle weakness (especially in your legs & feet)
-loss of movement in any part of your body.
-joint pain or swelling

Do you think that the muscle tightness could possibly be related to any of the side effects mentioned above?

You can learn more about this drug on the page for Eliquis Details

I hope this info helps!

Post a Reply   Share page   Report post

Was this helpful?  1 0  
Larry Says:
via mobile
Thanks, my tightness and swelling is in my neck and upper back. I am stopping my statin (after 12 years) to see if that is the culprit and if not, I will go back to Coumadin.

Post a Reply   Share page   Report post

Was this helpful?  1 0  
olivia Says:
After taking Eliquis for ten days I began developing muscle pain. I contacted my doctor and his nurse told me to take Tylenol. Needless to say I stopped taking the medication. Five days have passed and I'm still having these symtoms. Should I be worried? The nurse told me after five days the drug should no longer be in my system.

Post a Reply   Share page   Report post

Was this helpful?  12 1  
Ethel Says:
Hello Olivia,
How long did it take before you saw a change in your body after getting of Eliquis....
My Mother experienced the same joint pain and extreme fatigue. She has been off 3 days, but no change at all.

Post a Reply   Share page   Report post

Was this helpful?  9 1  
Annare Says:
Yes! My legs are stiff. It's difficult getting out of the car or bed! I'm 63 and felt fine before I started taking these new meds. First it was Xarelto, which caused back pain; now, it's Eliquis and I feel stiff all over!

Post a Reply   Share page   Report post

Was this helpful?  8 0  
Bill Says:
I am hving cervical neck pain also, along with hip pain. I stopped Eliquis several months ago to get injection into hip and my joint pain symptoms disappeared. More recently, I had severe neck pain along with muscle spasms. My MD gave me an injection of an NSAID. IN two hours I could turn my head fully. So I contacted my Cardiologist about discontinuing Eliquis for 3 weeks while I took Motrin to see if NSAIDS would help. Much to my surprise, within 24 hours after stopping Eliquis my neck pain had a noticeable reduction. Plan to only take an aspirin for a few days to see if neck pain is related. More studies needed on cause and effect of joint pain while taking Eliquis. Recommend contacting manufacturer and filing report with FDA. Maybe related, maybe not, but needs to be researched.

Post a Reply   Share page   Report post

Was this helpful?  14 2  
Eric Says:
Is there anybody out there without any side effect?
Please let us know.

Post a Reply   Share page   Report post

Was this helpful?  2 0  
Bill Says:
If related to Eliquis, pain should subside within 36 hours. If you are taking a Statin drug, it might be the cause.

Post a Reply   Share page   Report post

Was this helpful?  2 0  

Eric Says:
Hi all,I'm on Eliquis and Statin for about 9 months.I have a hard time getting out of bed in the morning.Stiff back and pain all over,legs,arms,shoulder and back.I'm 74.
After BF I force myself to ride my bicycle first very slowly and go for about 5-10 miles.After getting home pain is gone for the rest of the day.If I don't bike I'm in pain all day.I guess we all need more exercise even if we have to work trough the pain.Good luck

Post a Reply   Share page   Report post

Was this helpful?  3 0  
Janice Says:
I have muscle pain in my neck and in my legs and take eliquist. I complained in the hospital about the neck pain and got no response to it. I don't think they were giving me eliquis yet because what I was getting was in an IV. I was given an antibiotic and maybe I was given the eliquis. I know it was the day before I left the hospital I got the neck pain and I still have it.

Post a Reply   Share page   Report post

Was this helpful?  0 0  
Bill Says:
Since responding last year about neck and hip pain that went away when I stopped Eliquis to get hip injection for diagnostic purposes, i resumed Eliquis at the insistence of my doctor. Then I had cervical neck pain & muscle spasms so bad that my doctor sent me for a myelogram. Once again, I discontinued Eliquis in order to get Myelogram. Two days later I was pain free. When I discussed with cardiologist, he stated that ( was the only patient who complained about this.

I asked him if he asked his patients about joint pain since most would not correlate this pain to Eliquis.

In prior years, I had total body muscle pain while on statins.

When I contacted the Pharmaceutical company about Eliquis joint pain, they said it was in the Product Information circular. It is, but is very well disguised. Suggest everyone with this side effect contact Bristol Myers Squibb and file an adverse event report, and make sure your doctor knows about it every time you visit him/her.

Post a Reply   Share page   Report post

Was this helpful?  15 0  
kathy Says:
Yes I have been so sore and stiff in the mornings it's like I've aged 5 yrs. I've also had extreme nausea that I have taken meclizine for. I just went off of it for 3 days for a dental appointment tomorrow. I am considering staying off it and going back yto coumedin.

Post a Reply   Share page   Report post

Was this helpful?  6 0  
Will Says:
I got really bad neck pain I have to stop Eliquis!!!

Post a Reply   Share page   Report post

Was this helpful?  6 0  
Bill Says:
This is not indicative of aging. If you have the least bit of arthritis, the inflammatory process stimulates the production of Platelets. If taking anticoagulants, it somehow interferes with normal platelet function.

Discuss with your doctor, and file a report with the manufacturer.

Post a Reply   Share page   Report post

Was this helpful?  11 0  
cynthia Says:
At first on Eliquis my back was very stiff...gradually it went away in several months...I used to have a lot foot pain before taking seems to have improved after taking it. My cervical neck arthirits and upper body pain however seems worse...not sure if, it's Eliquis or from auto accident injury several years ago.
Seems like missing doses and screwing around with dose times makes bruising worse too. Try to stay regular...I have been on it since October 2013..

Post a Reply   Share page   Report post

Was this helpful?  0 1  
Janice Says:
Oh, yes. I was and energy plus person and now the muscle aches in my legs and neck are bad. I have no energy and feel much older. The neck pain came after taking two eliquis. They also gave me Toporal twice a day (50mg) and that could be part of it. I have circulation problems in my toes and fingers too.

Post a Reply   Share page   Report post

Was this helpful?  4 0  
Clair Says:
I just started eliques. and could not belive that all of a sudden had a lot of muscle pain,neck,back arms. i decided to check for side affects and now i know it is the eliquis.

Post a Reply   Share page   Report post

Was this helpful?  11 0  
Bill Says:

Post a Reply   Share page   Report post

Was this helpful?  7 0  
Dee Says:
After taking 5mg Eliquis 2x/day for 2 months, I now have neck,shoulder and back pain. I also am beginning to have hip discomfort. I was fine before Eliquis. Is it all a coincidence? My cardiologist said my symptoms not a side effect

Post a Reply   Share page   Report post

Was this helpful?  6 0  
chris Says:
Its not your imagination. I am taking eliquis 5 mg twice a day since march 1 2015.
The last month I started getting muscle pain in my arms and stifffness in my
hand joint. I am having getting off a couch, kichen chair and a Toilet seat.
Getting in and out my car is difficult. I am a pharmacist for 38 yrs and I am 61 yo
and now going to a Rheumatogist . She on a witch hunt thinking it might be gout.
After reading these blogs i am convinced the smoking gun is eliquist.
I got to have them get me off this crap before i turn 62 sorry i mean 92!!!!!!

Post a Reply   Share page   Report post

Was this helpful?  20 1  

Viewing page 1 of 10     Reply

Next Page >

More Discussions:

Extreme fatique, joint pain, muscle weakness with Eliquis for AFIB

I was having extreme fatigue, joint pain, muscle weakness after starting Eliquis and started to having black stool with ... 66 replies

Muscle pains taking Atorvastatin and Lisinopril

I've been experiencing muscle pain while taking Atorvastatin / Lisinopril, and have to take Co-Codamol just to be ab... 5 replies

Muscle pain all over with Eliquis

I have been on this medicaion now for a month and have increasing aount of pain all ver my body and sleep disturbance wh... 6 replies

joint and muscle pain eliquis

since being on Eliquis after cardiac ablation, for a-fib my leg muscles hurt so bad hard to walk. Have dizziness serve p... 16 replies

Extreme joint and muscle pain, neck stiffness, tightness of chest while on Eliquis

The neck stiffness started while on Xarelto. After switching to Eliquis is the pain spread throughout my body. Into my b... 22 replies

Is it ok to use benzos and/or muscle relaxers while in prerequisite withdrawal?

Hello, I'm starting the prerequisite withdrawal period before my first suboxone appointment. I would desperately lik... 1 reply

nerve pill with muscle relaxer

I have a saincation on body feels my musical or never getting weck verey uncountable to relax mosy whin seating its not ... 1 reply

muscle aches and linzess

I have been on Linzess for a month. My dose is now 1 every other day. I am still waiting to see if the diarrhea subsides... 3 replies

Xarelto with back, joint and muscle pain

If anyone else experienced these symptoms, how long after being off the xarelto did symptoms go away? ## According to th... 31 replies

Clindamycin and joint/muscle aches

Hi, I've been on Clindamycin 150mg x3, 3 times a day to treat SI Joint MRSA. I've taken this for 11months. I sta... 5 replies

Post a Reply

No registration is needed.
Simply fill out the form below.

Please be detailed.

You may use your first name, or for more privacy, make up a nickname.

Optional. Always hidden. This allows us to notify you when a reply is posted here.

4) Text Verification: *
Prevents SPAM.

Click here to show the question

This form will be submitted securely


Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.

Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. Site content is Copyright © 2005-2018 and is protected under U.S. and International Copyright laws. All Rights Reserved. This page was last updated on 18 March 2018.

We are committed to your privacy.

Copyright © 2005-2018 All Rights Reserved. MedsChat® and The People's Medicine Community® are registered trademarks of Limelight Innovations L.L.C.