Jakavi Ruxolitnib

I have been takining this drug Jakavi for 18 months for the treatment of Myleofibrosis. My spleen has reduced in size, my blood levels are much closer to normal range except for the Haemoglobin which is low. My concern is that since the commencement of the course of the drug my PSA level has increased drastically. Has anyone else experienced this?

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Further: my most recent PSA reading is 27.5 and have had a Biopsy of Prostate which is negative of cancer. Could drug Jakavi or Ruxolitnib or the Myelofibrosis be influencing the PSA reading?

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Am on Jakafi 20mg twice a day for last 2 years and recent psa increased from 5 to 16 over that time. Am going to dr tomorrow to check about biopsy so will try to match my info with yours, but from my readings it is a possible side effect.

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I hope anyone can share with me if you are currently on Ruxolitinib. I was on Ruxolitinib 40mg each day since sine Dec 2...