Jakafi Side Effect

I am taking 30mg a day for Polycythemia and have a side effect which is puzzleing. Suddenly I have no saliva and raw inside cheeks. Also, water tastes sour. Has anyone else had such a strange side effect? Been taking the drug since March 2014, and aside from weight gain and tiredness, no complaints.

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Hello, Chinchie! How are you? I'm very sorry about the problem that you're having.

According the side effects listed by the FDA, mouth sores have been reported with this medication and virtually any medication may cause dry mouth, you may also experience cough, nausea and easy bruising.

However, I didn't find anything about the change in taste, but there's a chance that's just due to the mouth sores.

Have you had your doctor look at them, yet?

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Jakafi can cause dry mouth. You need to stay hydrated. The rule of thumb is to drink half your body weight in ozs of water. I weigh 124 lbs, therefore I drink 62 ozs. Of water daily.

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