Harvoni Side Effects

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Tony Says:
 
I have been taking Harvoni for 3 months now and am having nerve pain in my legs and lower back pain. Is anyone else taking Harvoni having any of these same side effects as me? Please help if you are able. Thank you

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David Says:
 
Hi Tony,

From what I've researched, "lower back pain" is specifically listed as one of the more common side effects of Sofosbuvir (the second active ingredient in Harvoni); so I'd imagine that "leg pain" may be attributed to this drug as well.

If you'd like a more concrete reference, "back pain" is also listed as a side effect of Sofosbuvir on Pubmed at:
ncbi.nlm.nih.gov/pubmed/25422576

That said, you may want to contact your doctor if the pain becomes too bothersome or severe. This way you and your doctor can determine if Harvoni is still right for you.

I hope this helps!

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Tony Says:
 
Very helpful Thank you so much. The doctors all tell me the same thing "Keep Taking It or it will come back the hepC." No matter what I tell them they all want me to stay on .

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Eddie L Says:
 
Hello Tony. Yes, I have been having knee pain and swollen right knee, as well as back pain. I am currently at week 11, of 12 week treatment. I was told but the treatment team, that this was not a reported side effect. Glad to hear that I am not the only one. Thanks...

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Charity Says:
 
I have been having a lot of nerve pain in my legs as well as my arms and had wondered if it was Harvoni related. I am in week 10 of treatment. I'm glad to know that this is probably a side effect.

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JoeP Says:
 
I recently was approved to start using Harvoni. The Dr. has never told me what my viral counts are and they say I may experience some headaches & some heartburn. After reading some posts from Harvoni patients, I see its a little more than just that.Do I have some fears that other side effects will occur....... yes. I dont feel I can handle more set backs, my energy is low & pain level is about a 6-7........You see I'm in my 2nd. mo. of re-cooperating from cancer surgery and dealing with a colostomy & 2 deep muscle flaps in my butt.

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6
Charity Says:
 
JoeP, I am very sorry to hear all that you are going through. It is hard to advise you one way or the other on Harvoni given your situation. I can only tell you from my own experience that the side effects have been sporadic and have never been so bad that I didn't feel like I could continue on with treatment. Everybody is different, so I don't know if that is the case with other people or not. Personally I had more energy for the first six weeks or so, but I think the insomnia has caught up with me and made me more tired here at the end of treatment. I only have one more week, so I definitely feel like any side effects I have been through have been worth the result. Hope this helps!

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Robert Says:
 
I am in week eight, only four weeks to go. The headaches are almost daily, as is the nausea which was stated in all I read. I have been having some real back pain but I have had back issues in the past so not sure what the story is on that one. For me there is no turning back, I will complete the last four weeks regardless of side effects. The back pain is in my lower back on the left side and it is a bit debilitating at times. This is first I have heard about back pain being a side effect. It got so bad I went to the emergency room and I have to be hurting to go there. The pain radiates (at times) into my left testicle, again strange. If it is a side effect I can deal with it, the other option is not really an option.

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JoeP Says:
 
dear Charity............ Thank you for your input in which I truly respect. I waited this long to respond because I wanted to wait until I heard from staff on my decision (it only took 3 business days to hear back) amazing.......... But anyway I told them I am not ready to take any kind of issues associated with this medicine until I feel 90% healed from my operation, I cant handle more setbacks @ this time.

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9
Sandy Says:
 
Tony........I just finished my 12 weeks yesterday but, for the last 4 or 5 weeks my legs have been aching really bad, especially when I walk. I have had no problems with my legs ever, so it will be interesting to see if the aching goes away now that I'm finished with the Harvoni.

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10
Sassy Says:
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Same here. I completed my harvoni. Now have severe pain in left knee and my back. Have to walk with walker now.

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Stef Says:
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Yes! The pain in legs, back is horrible..Nothing works.

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Sandy Says:
 
I took Harvoni for the 12 week program with no side effects and the virus is undetected. The doctor follows up with blood tests for quite awhile. I just hope it stays undetected. I too got nerve pains in my legs after the Harvoni. I took my last pill on the 24th of May. I went to a Vascular doctor because I didn't know what the problem was. He said my veins were fine. I suspected the Harvoni and now that I hear someone else complaining of the same problem, I'm thinking maybe it IS the Harvoni. My legs are getting a little bit better the last 3 or 4 days, so I hope it goes away. Maybe yours will too.

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jenna Says:
 
i'm sorry to hear about all the discomfort you are going through. i finished my medication almost two weeks ago. I've been having the most severe lower back pain and it is in goes down into my groins. Like you i've had a history of back pain so i'm used to it. But this is just terrible. Going to the chiropractor doesn't help except for a short time. anti inflammatories help but not for long. It's piecing debilitating pain like i've never had before. I think of going to the emergency clinic it's so bad..but i just keep thinking that it will get better.I keep think that if i just stay as reasonably active as i can it will get better. i hope your're better by now! and everyone who has suffered side effects will get over them quickly.

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14
jenna Says:
 
Does anyone know if the back and leg pain or any of the other negative side effects go away? I've been off meds for about 10 days but still have them.

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15
pax12 Says:
 
Take Harvoni at night before bed and have 2 bottles of water by your side. Make sure you drink the water during the night and use the bathroom. The morning will feel tired but as day progresses you will feel much better. When you feel flush or weak drink water.

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jenna Says:
 
thanks so much! this is new territory so it is nice to get some good ideas!

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Cat Says:
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I finished an 8 week course of Harvoni last day in March. Prior to treatment I did research the 2 products, especially carcinogenic studies. One of the ingredients is still "being tested" which spelled trouble to me but I had waited 35 years for a treatment and needed to do something. All pre treatment sonograms, etc showed absolutely no liver damage, unremarkable gallbladder and pancreas .2 months post treatment showed sludge in my gallbladder ( I'm a vegan) and 3 months post treatment I now have a gallbladder cyst that is a precursor to biliary Cancer. The drugs are metabolized by Bilary system and pancreas , kidneys and gallbladder are all being impaired!! Be leary, I am starting to feel that Cancer of the biliary system could be a side effect of treatment. I will keep you updated...

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18
Cat Says:
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It goes away about a month to month in a half later

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Stef Says:
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No it doesn't. I think it depends on person. I've been thru with meds since February. Unfortunately, I now walk with a walker, when I can walk. I can barely stand longer than a half hour and no I did not have trouble before.

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Sandy Says:
 
Stef........are you saying that Harvoni has caused you to not be able to walk?

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