Generic To Welbutrin

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Is anyone having trouble with the new generic for Wellbutrin? It doesn't seem to be working as well. I hesitate to go back to the original Rx since it is so expensive. HELP.

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1

i just took generic and don't know it that's the reason I have been feeling more energy and some wakefullness at night.

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2

There are many people who have been having a problem with it, though the FDA says the differences are insignificant.

In reality, generic medications DO NOT have to be exactly like their name brand counterparts.

They are allowed to differ in the ACTIVE ingredient by plus or minus 20%.

In addition, the ingredient used DOES NOT have to be the same, they only have to prove that it is 'biologically equivelent' and works in the body in the same manner as the name brand did.

The inactive ingredients DO NOT have to be the same at all, they are allowed to be entirely different.

With such possible changes, this does create problems for those people who are sensitive to them.

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3

I've been on the generic (Budeprion XL) for a month now and notice a difference from the brand Wellbutrin. I'm not sleeping again, have a sleep deprivation headache and am eating for no reason. On Wellbutrin XL, I was starting to feel better, but, my health insurance insists I try the generic. I'm going to request a prescription for Wellbutrin as soon as this trial is completed. The 20-30% allowable difference in the generic and brand must be enough to make a difference, at least for me.

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4

Wellbutrin and its generic Buproprion are NOT the same. You are correct, and this was confirmed by my doctor when I casually mentioned that the generic wasn't working the same. My doc is a psychopharmacologist—should know a lot about this — and does.

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5

Hi there. I think sometimes generics work less well for people than the brand because of the psychosymatic (Sp?) effect. You think it won't work as well so it doesn't. As a Pharmacy Intern I can tell you that generic drugs are not allowed to differ in active ingredients from the brand by up to 20%. In order to be approved by the FDA they have to have the same amount of the active ingredient as the brand; inactive ingredients can be different but they do not affect the overall potency of the drug. Generics are cheaper because the companies that make generics do not have to spend the millions and millions of dollars in drug research and trials as the original maker of the drug did. You have ten years from the date a drug is 'discovered' before a generic can be released. By the time most drugs get to the market they have about 5-7 years to make money before the generic can come out. Some drugs will almost never have a generic either because the market for it is small or because it can't be manufactured cheaply enough for the company to recognize a profit.

Hope this helped.

I have been on the generic Welbutrin and it didn't work any worse, or better, than the brand.

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6

Hope my research can be helpful. My husband found a very big difference between Wellbutrin SR and XL. Health insurance would not cover the medication. I did some research to find out how to obtain Wellbutrin XL the cheapest but safest way. First, I read the bottle we purchased at the drug store and Wellbutrin XL is manufactured in Canada by a company called Biovail. Secondly, found that the AARP's website provides very detailed instructions on how to purchase medications safely from Canada and rates Canadian pharmacies. We have been ordering Wellbutrin XL from a Canadian pharmacy without any difficulty. In fact, I jjust ordered Wellbutrin XL 150mg tablets, 180 tablets for $196.04. Check out the website AARP.org for more info. The same amount of medication purchased at a retail pharmacy in the US was over $900.

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7

i would like to know what the Generic pill Bupropion looks like. The reason is because When I was taking the Wellbrutin it would hurt my stomach real bad, that's why my Dr. changed my medication to Generic.

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8

This Generic pill doesn't look at all the the ones I was taking before my new refill. Wellbrutin pills make me sick so my Dr. ordered the Burpropion ones. I have the Generic brand right now but the pills look like the ones of Wellbretins & my stomach is in pain.

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9

I was put on wellbutrin xl in 2006 and 2 months later without notice, I was given Budeprion xl. ( Both were 300 mg.) For about 1 year I have been very irritable, angry, crying for no reason, in general, just miserable. Has anyone had this effect after about 2 years of taking Budeprion xl? I am a 40 year old female. Also, Someone mentioned it could also be perimenopause symptoms. I haven't been able to work for 10 years due to depression. Now I want to go to work but these symptoms are unbearable. Can anyone provide any help? Thank you.

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10

5th day on wellbutrinXL 150 for 5 nights now - no change whatsoever from the depression. Crying more and no appetite. I cant even have a normal conversation with my husband - he doesn't believe in depression and he gets so mad at me. How long does it normally take to start working cause I don't know how much longer my husband will put up with this!

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11

I have been taking Wellbutrin for over twenty years. I have never had adverse side effects. I began taking it for depression. What amazed me is i stopped having rage anger. I was thrilled. Along came the generic and of course my insurance company wanted me to switch. After two months the rage anger came back. My doctor changed me back and I stopped the rage anger. Since Obama care, my insurance company is harassing me to change. through the years I have had several doctors tell them that I need the name brand. Now my insurance company not only refuses to pay the full price as the did for 18 years, they. will only pay one half of what they would pay for the generic. feels like retaliation to me.

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12

I've been taking 150mg of welbutrin for 2 months I still feel so depressed, I am also taking 100mg of seroquel for bipolar disorder which has worked so for, could the 2 meds counteract each other? Or do I need to take a higer dose of welbutrin?

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13

I've been taking wellbutrin generics 100mgs/dy for 4-5 years with good results. however lately i feel as though my depression has returned. in the past i discovered for me the manufacturer of the generic makes a difference but am currently on the one that has worked for me over the last 4-5 years

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