Afraid Took Movantik With Linzess Very Bloated Help

I have multiple sclerosis and my doctor gave me movantik I took it for 3 days and it worked but I went into terrible withdrawal. It worked then it stopped working. another person told me to take it with linzess and I did not go. two nights ago I took miralax I went to the bathroom yesterday a few times however today I am so bloated i am afraid. please help

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Hello, Rifka! How are you?

Linzess is known to cause bloating as a side effect as reported by the FDA, the Miralax can also cause it. It can also be a symptom of constipation, thus you've got several good reasons for why you may be bloated.

However, if you're concerned, you should consult your doctor, they may be able to help you alleviate it and perhaps give you a more accurate idea as to its cause.

Are you on any other medications? Do you suffer constipation frequently?

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Movantik is contraindicated if there is any damage to the blood brain barrier, something I imagine could be possible with MS.

It is called a "peripheral opioid antagonist", and is made from naloxone with an added component that greatly limits its ability to cross an intact blood-brain barrier, so that opiate effects are only cancelled outside the brain, i.e. in the gut.

"peripheral" in this context means "outside the brain."

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