Zonisamide For Dog Seizures

5 Replies Updated



Conversation Starter

Robin Says:


I just wanted to let people know that I felt the vets did a poor job of believing the secondary symptoms of zonisamide. My dog, Ivy, has been having seizures for over a year now and we started with phenobarb, which she is still on, Zonisamide about eight months ago. The Zonisamide made a small difference in the primary seizures but she started having dry mouth and coughing almost immediately, then after several months, reddish patches on her left side and sores inside on the right side of her mouth (much less on the left side of her mouth). Three or four different vets tried to tell me she was just going to bleed out and I should put her down. I demanded that we start Lyrica and gradually take her off the Zonisamide. Lyrica is more expensive, but I have found that the improvement is well worth the expense. It was an uphill battle since when her minor seizures would reoccur (which I could tell was because of the reduction of Zonisamide) the vets all implied it was just her primary seizures and they did not really encourage me to try the change to Lyrica. In other words, since I was unexperienced in the process of reduction actually being the cause of reoccurrances and how they differ from primary seizures it was very disturbing and undermining to my confidence in my gut feeling of what was going on and to stay the course. They were much more intermittant and short, but very strong. However, the secondary symptoms all seemed to clearly, albeit, very gradually, improve. I am still holding a close eye on the phenobarb and am hoping maybe to be able to transition to only the Lyrica. This process will take at least another six months. Also, imo, the Zonisamide was also the cause of her being much more unaware of her surroundings and who I was.



Showing Replies 1 - 5 of 5 RSS Feed


of 1    
1
David Says:

I find it odd that the vets prescribed Zonisamide as a first line of treatment over something more natural. In my opinion dogs or any animal for that matter should probably not take medications that were made for human use. With all the side effects, withdrawal symptoms, binders and fillers, one has to wonder how it really is affecting their system internally and for the long run.

Hopefully Lyrica continues to work well for her. I just know we humans have been reporting some serious side effects with both of those drugs here on this site and would worry that it may be too much if taken for a prolonged period of time...

Have you noticed any other behavioral changes in your dog since taking Lyrica?

REPLYSHAREREPORT
Was this helpful?     1     0  
2
Felicity Says:

Hi I have had my 6 year old Labrador on Keppra 1000mg 3 times daily and 75mg Lyrica 3 x daily plus 3ml potassium bromide 1 x daily and she is definitely more uncoordinated and has excessive thirst and appetite since the Lyrica was introduced 3 months ago. Her seizures are still not well controlled but the phenobarbs where starting to cause liver damage so had no choice to try an alternative. She raids dustbins, takes food off counters and now submerges her entire nose under the water when drinking and this all began when the Lyrica was introduced. The specialist vet looking after her is considering increasing her Lyrica to 100mg 3 x daily to see if we get better seizure control but I am not sure its the best idea with the changes I have seen already......

REPLYSHAREREPORT
Was this helpful?     0     0  
3
Reno and Brittany Says:
via mobile

My 8 year old Rat Terrier has been suffering from epilepsy for about two years. Her initial doctor said if she only has them rarely she more than likely wouldn't need medication. And for about a year they came once every 4 months. But this last year they gradually started happening 4-6 times a month. Sometimes in clusters. Or 2 within 48 hours. So today we decided to take her to get on meds. Her vet prescribed her zonisamide. 25mg twice daily. Again she's a 7 lb female rat terrier, 8 yrs old, with severe anxiety. I just was wondering if anyone could give me an outlook from a similar situation by a dog owner, not just one veterinarian. Because we all know some of them make mistakes :(

Thank you,
Brittany and Reno Pup

REPLYSHAREREPORT
Was this helpful?     0     0  
4
Ken Says:
via mobile

Sorry to hear about your puppy. I want pet owners to know that my eleven year old Golden Retriever had to be recognized today as a direct result from an initial dose of zonisamide. IT IS NOT SAFE. Her seizures were happening once a month for about six months. I took her to the vet who prescribed zonisamide 400 mg a day in two doses. I was apprehensive about the amount and the drug so I got the meds but did not start it immediately. While on vacation the following month she start seizing once a day and progressed to 5 episodes a day for two days. I decided to start the meds. The first 200mg was given that evening. The next morning she was very confused but hadn't convulsed all night so I gave her the second 200mg dose early morning. Within 3 hours she was in acoma and remained so for two days. She never recovered and I put her down the third day. The vet had followed the recommended dose . I looked up the drug so many times and finally found the recommended dosing in the PDR. It recommended one forth the dose that the vet did. Do your homework before giving this drug! I have lost my best friend.

REPLYSHAREREPORT
Was this helpful?     0     0  
5
Sue Says:
via mobile

Re: Reno and Brittany (# 3)

I have a 5 year old Chaweenie that weighs 12 lbs. She stated having seizures at 11 months old. She is on zonisamide since then. She only had one or 2 seizures a year sms they are mild. We had added Gabapentin last year due to suddenly losing our big lab, she had a day of cluster seizures from anxiety.that was a year ago. She takes 1 25mg zonisamide 2x day and 1 100mg gabapentin 2x day.. it's working and she's doing quite well.. You have to have a vet you trust

REPLYSHAREREPORT
Was this helpful?     0     0  


Viewing page 1 of 1     Reply


More Discussions:

Is Zonisamide for mirgaines
it read that it's for controlling seizures (epilepsy). Nothing about migraines. ## can you explained why it was give... 4 replies
What Is Zonisamide Used For
I do have pain issues, spasms, weakness, neurological/muscular issue not diagnosed yet, myoclonic jerks...peripheral neu... 1 reply
seizures for my 3.5 years old son
Dear Doctor my son is 3.5 years old and since last two months he is getting fits and we have consulted nurologist and ta...
ep for seizures
My son is suffering from seizures. From last five years he was on eptoin (syrup 12 ml a day). Last February doctors advi...
medicineforabsence seizures
I am suffering with low grade glioma since 1997 but now I have started with 5 to 7 times absence seizure now I am on ept... 2 replies
I Have Been Taking Xanax For 3 Weeks Straight And Now Want To Stop But Am Afraid Of The Seizures What Do
I am afraid to just stop taking Xanax I have been taking a bar a day for 3 weeks n now I want to stop what do I do? I am... 9 replies
Hi There Im 26 Years Oldi Have Epilepsy Since My Childhood But After Taking Medicines For 3 I Went Normal Never Got Seizures Again Lately In Mar 2009
hi there, I'm 26 years old.I have epilepsy since my childhood. But after taking medicines for 3 years I went normal ... 3 replies
ZONISAMIDE 100mg ?!?!?
So I took this med all month last month, ZONISAMIDE 100mg they were light green and white. White side said 100. Light gr... 3 replies
zonisamide, oxycontin, grapefruit, birth control
How much will zonisamide affect oxycontin? I started both meds together. The oxycontin is temporary because of dental wo... 2 replies
Zonisamide
APO 100 Capsule ## Based on the description provided, I found your pill to be Zonisamide (100 mg). Zonisamide is a sulfo... 1 reply


Post a Reply

No registration needed.
Simply fill out the form below.

 *

 *


 Optional, stays hidden.
Get notified when a reply is posted here.




4) Text Verification: *
Prevents SPAM.

Show Verification Text


with the privacy policy (20210315).


This form will be submitted securely
Privacy policy cookies information

TRUSTe

Discussion Thread Guidelines: Any participation in the discussion threads signifies your agreement with the Terms of Use and Privacy Policy. (1) Act civilized and be respectful towards others. No profanity, vulgarity or lewd / suggestive content is allowed. (2) Posts encouraging, facilitating, or seeking advice about the abuse of medications or other substances are prohibited. (3) Personal contact information (such as telephone numbers, email addresses, etc) is not allowed to appear on our discussion threads. (4) We do not allow our forums to be used for buying, selling, trading, or for the promotion of a product or service. (5) Posting external links to other web sites is not allowed without our prior approval. (6) We reserve the right to edit or remove content which we find objectionable to the community at our sole discretion.


Note: All times displayed are GMT - 7.

This information has been independently compiled and is for informational purposes only. It is not intended to be a substitute for medical advice from a qualified healthcare professional; nor is it intended to diagnose, treat, cure or prevent any disease. For more details please see the Medical Disclaimer. This page was last updated on 12 August 2018.

We are committed to your privacy.

Copyright © 2005-2021 All Rights Reserved. MedsChat® is a registered trademark of Limelight Innovations L.L.C. 9888 W Belleview Ave #5000, Denver, CO, 80123, USA