White Buprenorphine Round 460 (Top voted first)

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So I went to the pharmacy yesterday to get my script and they told me they were out but they would have more tomorrow. When I picked my script up it wasn't what I normally get. They told me it was a generic but I have never seen them before and I have been in treatment for years now. I have tried looking them up but can't find any reviews or anything really on them. Has anyone ever gotten these? And do they work as good as the 54 411? Also it is kind of minty which reminded me of suboxone and I'm not prescribed suboxone.

62 Replies (4 Pages)

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5

I don't know where you are from, but we had been hearing the same thing here in our area (Ohio, West Virginia, Penn.)... Read til the end, I do have the answer!... One pharmacist said they weren't sure why they hadn't been able to get a supply but he'd doubt they'd stop manufacturing them because, another said these 460 were the replacement, and two people even told me crazy stories like that some type of vehicle/vessel/train or whatever, was transporting the meds and had an accident and that was the reason, another saying they were on back-order until 7/17. But then I attempted to contact the Lab myself, to find out the real story. Another company, just closed on a 2.1 billion dollar buy of Roxane Laboratories (manufacturer of the white, round, 54 411 imprinted tablet buprenorphine) and that is the reason. I believe we are now being supplied with this new company's brand of buprenorphine from this point forward. Unfortunate, as most of us know, the Roxane tablets were much more effective with less side effects compared to other generics but this of course will not affect the other brands if you prefer one of those (Mylan, maker of M924 imprinted tablet; Hi-Tech, maker of small, round, arrow imprinted tablet, Teva, Akorn, etc.... Now the funny thing is, I keep seeing reviews stating that their new medicine (460) has a "minty, Suboxone-y taste" and that is not the case for mine. Also, one review in which the reviewer mentioned that taste, stated the name of the manufacturer, which is different than the manufacturer on the new white, round, 460 imprinted tablets I got. Because mine are DEFINITELY not minty. They do have an intense, and I mean intense, burning sensation while dissolving under the tongue. Incredibly more intense than any other. And that's only with a half dissolving at a time! Anyway, hope this information helps someone. I know I myself was frantically searching for answers, just hate being in the dark with my recovery when it comes to changes, as I'm sure others would agree.

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3

They do not work for me like the 54411. I'm trying to get my pharmacy to swap the remaining ones I have. I've had the worst cravings in three years on these and I'm about to go nuts.

Was this helpful? 5
14

People (Heather)! If you don't have valid information don't respond with some stupid rumor that might scare people on this medication. Rediculous

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1

I just got them too. Ive never seen these before either but i dont notice the difference in how they work. They pretty much work the same.

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16

These are awful! I've been on Subutex for years (mostly because I've been pregnant and or breastfeeding Everytime I try to taper off) and I got the 54 411 ones. Then CVS gave me these and they taste awful! I switched pharmacies so this month the mom and pop one I go to gave me the orange diamond shaped ones with the moon print on them. They're way better than the little baby white ones. So I misplaced my prescription and I remembered I have a few in my old bottle so I took one. Instantly got a headache and am so nauseous. I feel like im going to puke. Worst feeling I've ever had! They should not be giving these to people. I think I may be having an adverse reaction to them or something
Also I heard that the company for the 54 411 pills got bought out and these little ones are the replacement

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6

I've been hearing that as well.What you expect from a company from India ...they got enuff problems . Where I live in Ohio the Dea shuting clinics down and pharmacy's too!! Sad Cuz people need help they make them suffer or go another way. I haven't seen them here yet but have talked to someone that got them and they said "there alright but don't like them" . Around here pharmacy's won't fill our scripts ,only if u find the needle in the haystack kind thing....God bless stay sober

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17

I just got these new 460 subs. They work just as good as actavis or mylan. I notice absolutely no difference. I cannot take naloxone, it gives me terrible headaches plus the bottle says buprenorphine only so there is no naloxone in these.

There has to be another variant besides these- the sun pharma bupe works fine for my chronic pain/past addiction issues.

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34

Re: Chris (# 31) Expand Referenced Message

Duude! I thought i was only one. U can dose then sleep 2 hrs n wake up sick. Thank u man! Thought i was only one im getting alot euphoria n warmth off the 460s after being on 54 411 rox for years. These (so far) feel BETTER to me. The hi techs are indeed garbage tho. Il keep yall updated. So far i enjoy these Sun 460s n i feel no diff. Only maybe a lil better. I havnt got a slight euphoria off subs in yrs on 54 411s n 8 arrows [hi tech] till these 460s. I get 60 8mgs a month. 2mg has me hungry. Feeling good n euphoric! Im in south NJ.

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4

I agree felt cravings w/460's. I just want to get back the 411's which have been working fine no problems no cravings in 6+ years. Not sure if it's just Cvs that "can't or won't" get the Roxane/Westward 54/411's, I'm in N.J & that's where a Westward manufacturer is located.

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12

Yes I don't like the taste the 460 pills leave! I am on Medicaid is SC and as if May they will only Pay for SubuteX not suboxone even though they have payed for my suboxone for 5 YEARS!!!! I AM HOPING THEY WILL WORK BETTER AFTER A COUPLE DAYS! They BURN

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20

The Sun brand (460) are indeed awful, with a very obvious lack of efficacy (they DO NOT compare to Mylan, MAY be comparable to Hi-Tech or Actavis I can't really say because it's been too long since I've had either of those) and the side effects are unbearable, and it's very unusual to me because I've never experienced side effects like that from ANY of the other manufacturers, besides lack of appetite - that one seems to occur no matter which one I take...... And in response to one of the recent posts, these are not a replacement for Roxane (54 411). Those were on back order for a bit, but they are still being manufactured and currently being shipped for distribution so you should have no issue, unless the pharmacy switched the brand of which they choose to order (only reason to do that would be cost). The only difference is that, yes Hikma bought Roxane, and Hikma is the parent company of West-Ward, thus they have merged the two companies as one, so you're prescription bottle should now say "Manufacturer: West-Ward" or "Roxane/West-Ward". That is the only difference; they are still the same white, round, 54 411-imprinted tablets, same efficacy, same medicine. I encourage you to report side effects and lack of efficacy!!! You can call your pharmacy's corporate office or FDA and also on Sun Pharma's website. That will get these big chain pharmacies to get rid of this and start stocking the preferred brand again!!

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22

The 460 are awful. Switch pharmacies, and stop spreading misinformation about tapering/switching to suboxone. If anything the pills are the gold standard, and Congress has banned other implantable long term methods in favor of Subs. Most places switched because Sun Pharma is cheaper, and they just got approval to manufacture the pills. I will say, though, that they were on a recent FRA ban list, though, and what you can do in the meantime is report them as ineffective. There's an awful good chance that they have too little buprenorphine in them. Sun Pharma has been plagued with issues, but their practices are what makes them dirt cheap.

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23

****FDA BAN (typo)

Google how to report the medicine as ineffective, and report them as being inferior.

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26

Re: Heather (# 7) Expand Referenced Message

Heather, you are so full of s*** it is coming out of your ears. Why bother looking up any info when you can just make up what you want. Right Heather!?!? Heather... it's your lie... tell it however you want to.

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32

Re: Jack (# 26) Expand Referenced Message

Heather is right. There is no naloxone in them. You wont go through WD if u take tge 460 before going through full WD like u would with suboxone. I like the 460 subutex actually

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33

Heather is right. There is no naloxone in the 460 and you wont go thru pre-med WDs if u take the 460. Not saying to use , judt stating a fact. Also, i like the 460s and dont get butning in my mouth or anything. They do make me drowsy as hell, but that will pass once u get used to them. I like them tbh.

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42

Re: riggsk0915 (# 9) Expand Referenced Message

When was this? I've been on subutex 10 years. I’m allergic to the narcan in suboxone. I won’t switch. F*** I’ll get my subutex elsewhere if I have to. The DEA has no authority to tell me which formulation is right for me.

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50

Re: Elly (# 4) Expand Referenced Message

Pharmacies are starting to be real rude with customers. If we were taking a certain brand give us our certain brand! wtf, they're not paying for it, we are. I pay cash cause my insurance won’t cover it so what’s the f*****g big deal

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51

Re: Chris (# 50) Expand Referenced Message

They are very rude and treat you like you're asking for heroin or something. Different generics make a huge difference. Also this big thing about subutex instead of suboxone is stupid because it’s the buprenophine that gets into the mu receptors and blocks other opiate narcotics. The small amount of narcan does nothing. In the ER if someone overdosed they have to give it over and over again.

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57

Re: Grapper (# 55) Expand Referenced Message

These pharmaceutical companies don’t give a DAMN about the quality of their generics. They fill them up with cheap fillers and dyes and God knows what else. Then they either buy the cheapest form of buprenorphine and as the smallest amount they can get away with. Then they charge exorbitant fees and probably know every single horrible side effects, PLUS the fact that, because the active ingredient is so dumb-par, that they are going to send hundreds, if not thousands of people, into excruciating withdrawals. They don’t lose a bit of sleep over it because they are too busy counting all the zeros in their bank accounts from making, pushing and selling horrible medication.

Let them remember this:

"Whoever sows to please their flesh, from the flesh will reap destruction." Galatians 6:8.

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