When Referring To Santly Collagenase Ointment What Is Meant By " And Help To Facilitate The Spread Of Gas Gangrene"?

Robert Says:

When referring to Santly Collagenase ointment what is meant by " and help to facilitate the spread of gas gangrene" ?

"Collagenases are enzymes that break the peptide bonds in collagen.

They assist in destroying extracellular structures in pathogenesis of bacteria such as Clostridium. They are an exotoxin (a virulence factor) and help to facilitate the spread of gas gangrene.

2 Replies

Earliest Newest Votes
Jenna Says:

Hi Robert,

Based on my research, I believe that "to facilitate the spread of gas gangrene" means that this product is intended to treat a Gas gangrene infection. The ointment must stop the spread of the infection and kill the bacteria.

Gas gangrene is rare in the United States. The condition is most often caused by a bacteria called Clostridium perfringens. However, it also can be caused by Group A streptococcus. Staphylococcus aureus and Vibrio vulnificus can cause similar infections.

Clostridium is found most everywhere. As the bacteria grow inside the body, it makes gas and harmful substances (toxins) that can damage body tissues, cells, and blood vessels.

Gas gangrene develops suddenly. It usually occurs at the site of trauma or a recent surgical wound. About 1 in 5 cases occur without an irritating event. Patients most at risk for this usually have underlying blood vessel disease (atherosclerosis or hardening of the arteries), diabetes, or colon cancer.

Information referenced from:


I hope this helps, do you have any more questions?

Was this helpful? 0
Byrdieman Says:

Santyl is the correct spelling.

Was this helpful? 0

More Discussions:

collagenase santyl ointment 250 units/g

can i use this ointment for fongus on my hand ## This ointment is usually used to debride chronic skin ulcers and severe...

how to stop the spread of gray hairs

I am 17 year old and I have many gray hairs please tell me how to.stop the spread of gray hairs ## @Niranjan, I do think...

tobramycin and dexamethasone ophthalmic ointment

ophthalmic ## i would like to know what this ointment is used for? ## This is an antibiotic and steroid that is commonly...

If I'm allergic to penicillin pills can I use the ointment?

I suffer from cystic acne and I use topical clindamycin but I found some penicillin cream in a Hispanic store and I was ...

gastric issue and use of pantosec d

I am 36 i had gastric problem the past 8 months. Am taking pantosec d continuesly Whenever the gastric issue i had. Plea...

After By Pass Surgery Of Heart The Surgeon Prescribed Clopivas Ap 150 For Life Long Use But It Causes Severe Gas Trouble What Should I Do

After by pass surgery of heart, the surgeon prescribed clopivas ap 150 for life long use. I take it at noon after food. ...

Suggested Percentage of Amitrip/Baclofen/Keto/Lido/Pregab in Ointment

A friend of a friend gave me some Amitrip/Baclofen/Keto/Lido/Pregab ointment to try for severe osteoarthritis hip pain a...

what is penicillin ointment used for

Good day everyone, pls can I use penicillin ointment against boils on my 7 months old baby? ## I have boil in my vagina ...

about the ointment clobetasok propionate and salicyclic acid

Mam I am 17yrs old I have a doubt about the ointment clobetasol propionate and salicyclic acid ointment. I went to the d...

are nystatin ointment and bactroban used for the same

I have sores in my nose I was just wondering if these two do the same ## Hello, Jane! How are you? No, Nystatin is an an...