What Oxycodone Dose Is Equal To 120 30mg Morphine Instant Release Monthly?

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Morphie Says:


I currently take 20mg methadone twice a day with MSIR 30mg tabs 4 daily=120 total. I am trying to find which dose of oxycodone would be the equivalant of my current dose of Morphine IR. Its been VERY hard filling that script for approx 6 months now and is getting worse. So one option is switching to another medication. Some of the problem is that medicine isnt used as much as it once was. My monthly appt w/ nuerologist is in 2 weeks...so please answer this ASAP Also if any brand names are know thats fine...my insurance will prob substitute generic but brand names help when talking to doctors. Thanks everyone!!!



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Verwon Says:

You would need 20mgs of Oxycodone to equal each 30mgs of Morphine.

This is a narcotic analgesic, so it has the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation.

Is there anything else I can help with?

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Absorbaloff Says:

Verwon, your assessment of relative opioid analgesic strength equivalence as always is NOT consistent with having the experience over 20 years; I feel you simply use the PDR or other equivalence table.
If I require 35mg oxycodone as a rescue dosage, then the equianalgesic dosage in Morphine sulphate IR (original Napp SEVREDOL brand! best on market ANYWHERE) would be in the region of 80mg. Oxycodone is NOT 1.5 x strength of MS. I assure you of that, and now there are several tables published reflecting that oxycodone is indeed stronger than has been published and accepted hey many for several years.
When trying to equate the two US-only drugs, high dose IR hydromorphone and oxymorphone HCl with the standard of morphine sulphate which ALL tables use as their reference point, please remember that these two inoarticular have such a high RANGE of dosages dependent on many factors particular to the patient in question; my hydromorphone dosage is anything between 10 and 14mg; using NHS PALLADONE capsules 1.3 and 2.6mg, between 11.7mg and 13mg. For oxymorphone, my metabolism and other factors mean I require 15mg more often than not. PALFIUM and dipipanone HCl seem to be around equianalgesic and I require 30mg prn of each.
There is NO absolute when comparing the analgesia gained by individuals using opioid analgesics, despite the attempts at making equivalence tables, which can only be taken as being accurate in that they reflect a certain percentage of non opioid tolerant patients; there is no alternative to proper titration on an individual basis.
You are great at book work, Verwon, but woefully short on personal experience, and dreadfully ignorant of the differences engendered by the metabolism and other functions of brain and body in patients being treated.
I value many of your posts but you can be inflexible, and this is an issue where flexibility is paramount.
I would love to know your take on the differentials between Hydrocodone bitartrate and its parent drug, more commonly seen and prescribed as now the USA is the only country lest which licences Hydrocodone, or as it really should be called chemically, DIHYDROCODEINEONE BITARTRATE, the parent being of course dihydrocodeine tartrate. Synthesis is carried out using raw dihydrocodeine BASE of course. Hydrocodone is also the most expensive of all opioids in relation to its strength and efficacy. How to justify such a weak opioid's cost when the equivalent of 10m, 40mg dihydro (DF118 brand 40mgtabs = 10mg Hydrocodone, previously available as DICODID and now only in the USA mixed with in feasibly high amounts of acetaminophen, apart from ZOHYDRO Sr, which has to be powdered as finely as possible to be of any use, that drug being In my opinion, FAR too weak to justify 50mg SR formulation. At least the acetaminophen has been dispensed with. I am, as you know, of the opinion that it should be a schedule 3 Controlled Drug AT LEAST as it is responsible for more deaths than any other pharmaceutical. Especially, demographically, in FEMALES between ages 12 and 18. Take of that what you will. Cries for help by ignorance of the dangers of a drug which is still available in Supermarkets in frightening quantities? At least in the UK packets are limited to 12 tablets and the price has been artificially raised.

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Tara Says:
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Not sure if you got your answer but oxycodone 30 is stronger then morphine ir so i would guess you would need to introduce ocycodone 30 to your tolerance try taking one 30 & if your pain is not tolerable take another as long as your scripts is written as such i just suggest taking the lesser amount first .I've been on pain meds for over ten years and I learned my body reacted differently then what other people had told me I should feel or would feel ! Best of luck to you hope your pain lessons for you !


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